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| Title : Discovery of MGS0274, an ester prodrug of a metabotropic glutamate receptor 2\/3 agonist with improved oral bioavailability - Urabe_2020_Eur.J.Med.Chem_203_112521 |
| Author(s) : Urabe H , Miyakoshi N , Ohtake N , Nozoe A , Ochi M , Fukasawa M , Kinoshita K , Yamaguchi JI , Marumo T , Hikichi H , Chaki S , Hashihayata T |
| Ref : Eur Journal of Medicinal Chemistry , 203 :112521 , 2020 |
| Abstract : Urabe_2020_Eur.J.Med.Chem_203_112521 |
| ESTHER : Urabe_2020_Eur.J.Med.Chem_203_112521 |
| PubMedSearch : Urabe_2020_Eur.J.Med.Chem_203_112521 |
| PubMedID: 32698110 |
| Title : Safety and pharmacokinetic profiles of MGS0274 besylate (TS-134), a novel metabotropic glutamate 2\/3 receptor agonist prodrug, in healthy subjects - Watanabe_2020_Br.J.Clin.Pharmacol_86_2286 |
| Author(s) : Watanabe M , Marcy B , Kinoshita K , Fukasawa M , Hikichi H , Chaki S , Okuyama S , Gevorkyan H , Yoshida S |
| Ref : British Journal of Clinical Pharmacology , 86 :2286 , 2020 |
| Abstract : Watanabe_2020_Br.J.Clin.Pharmacol_86_2286 |
| ESTHER : Watanabe_2020_Br.J.Clin.Pharmacol_86_2286 |
| PubMedSearch : Watanabe_2020_Br.J.Clin.Pharmacol_86_2286 |
| PubMedID: 32353162 |