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| Title : Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza (Danshen) - Hatfield_2018_J.Nat.Prod_81_2410 |
| Author(s) : Hatfield MJ , Binder RJ , Gannon R , Fratt EM , Bowling J , Potter PM |
| Ref : Journal of Natural Products , 81 :2410 , 2018 |
| Abstract : Hatfield_2018_J.Nat.Prod_81_2410 |
| ESTHER : Hatfield_2018_J.Nat.Prod_81_2410 |
| PubMedSearch : Hatfield_2018_J.Nat.Prod_81_2410 |
| PubMedID: 30351923 |
| Gene_locus related to this paper: human-CES1 , human-CES2 |
| Title : Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors - Binder_2018_Eur.J.Med.Chem_149_79 |
| Author(s) : Binder RJ , Hatfield MJ , Chi L , Potter PM |
| Ref : Eur Journal of Medicinal Chemistry , 149 :79 , 2018 |
| Abstract : Binder_2018_Eur.J.Med.Chem_149_79 |
| ESTHER : Binder_2018_Eur.J.Med.Chem_149_79 |
| PubMedSearch : Binder_2018_Eur.J.Med.Chem_149_79 |
| PubMedID: 29499489 |
| Title : Selective Inhibitors of Human Liver Carboxylesterase Based on a beta-Lapachone Scaffold: Novel Reagents for Reaction Profiling - Hatfield_2017_J.Med.Chem_60_1568 |
| Author(s) : Hatfield MJ , Chen J , Fratt EM , Chi L , Bollinger JC , Binder RJ , Bowling J , Hyatt JL , Scarborough J , Jeffries C , Potter PM |
| Ref : Journal of Medicinal Chemistry , 60 :1568 , 2017 |
| Abstract : Hatfield_2017_J.Med.Chem_60_1568 |
| ESTHER : Hatfield_2017_J.Med.Chem_60_1568 |
| PubMedSearch : Hatfield_2017_J.Med.Chem_60_1568 |
| PubMedID: 28112927 |
| Title : Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer - Wierdl_2016_Br.J.Pharmacol_173_2811 |
| Author(s) : Wierdl M , Tsurkan L , Hatfield MJ , Potter PM |
| Ref : British Journal of Pharmacology , 173 :2811 , 2016 |
| Abstract : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| ESTHER : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| PubMedSearch : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| PubMedID: 27423046 |
| Title : Carboxylesterases: General detoxifying enzymes - Hatfield_2016_Chem.Biol.Interact_259_327 |
| Author(s) : Hatfield MJ , Umans RA , Hyatt JL , Edwards CC , Wierdl M , Tsurkan L , Taylor MR , Potter PM |
| Ref : Chemico-Biological Interactions , 259 :327 , 2016 |
| Abstract : Hatfield_2016_Chem.Biol.Interact_259_327 |
| ESTHER : Hatfield_2016_Chem.Biol.Interact_259_327 |
| PubMedSearch : Hatfield_2016_Chem.Biol.Interact_259_327 |
| PubMedID: 26892220 |
| Title : Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors - Tsurkan_2013_Chem.Biol.Interact_203_226 |
| Author(s) : Tsurkan LG , Hatfield MJ , Edwards CC , Hyatt JL , Potter PM |
| Ref : Chemico-Biological Interactions , 203 :226 , 2013 |
| Abstract : Tsurkan_2013_Chem.Biol.Interact_203_226 |
| ESTHER : Tsurkan_2013_Chem.Biol.Interact_203_226 |
| PubMedSearch : Tsurkan_2013_Chem.Biol.Interact_203_226 |
| PubMedID: 23123248 |
| Title : Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza (Danshen) - Hatfield_2013_J.Nat.Prod_76_36 |
| Author(s) : Hatfield MJ , Tsurkan LG , Hyatt JL , Edwards CC , Lemoff A , Jeffries C , Yan B , Potter PM |
| Ref : Journal of Natural Products , 76 :36 , 2013 |
| Abstract : Hatfield_2013_J.Nat.Prod_76_36 |
| ESTHER : Hatfield_2013_J.Nat.Prod_76_36 |
| PubMedSearch : Hatfield_2013_J.Nat.Prod_76_36 |
| PubMedID: 23286284 |
| Title : Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11 - Hatfield_2011_Biochem.Pharmacol_81_24 |
| Author(s) : Hatfield MJ , Tsurkan L , Garrett M , Shaver TM , Hyatt JL , Edwards CC , Hicks LD , Potter PM |
| Ref : Biochemical Pharmacology , 81 :24 , 2011 |
| Abstract : Hatfield_2011_Biochem.Pharmacol_81_24 |
| ESTHER : Hatfield_2011_Biochem.Pharmacol_81_24 |
| PubMedSearch : Hatfield_2011_Biochem.Pharmacol_81_24 |
| PubMedID: 20833148 |
| Title : Carboxylesterase inhibitors - Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| Author(s) : Hatfield MJ , Potter PM |
| Ref : Expert Opin Ther Pat , 21 :1159 , 2011 |
| Abstract : Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| ESTHER : Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| PubMedSearch : Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| PubMedID: 21609191 |
| Title : Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones - Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| Author(s) : Parkinson EI , Hatfield MJ , Tsurkan L , Hyatt JL , Edwards CC , Hicks LD , Yan B , Potter PM |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4635 , 2011 |
| Abstract : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| ESTHER : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| PubMedSearch : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| PubMedID: 21733699 |
| Title : Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin - Hatfield_2010_Br.J.Pharmacol_160_1916 |
| Author(s) : Hatfield MJ , Tsurkan LG , Hyatt JL , Yu X , Edwards CC , Hicks LD , Wadkins RM , Potter PM |
| Ref : British Journal of Pharmacology , 160 :1916 , 2010 |
| Abstract : Hatfield_2010_Br.J.Pharmacol_160_1916 |
| ESTHER : Hatfield_2010_Br.J.Pharmacol_160_1916 |
| PubMedSearch : Hatfield_2010_Br.J.Pharmacol_160_1916 |
| PubMedID: 20649590 |
| Gene_locus related to this paper: human-CES1 |
| Title : Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes\/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2 - Xie_2010_Chem.Res.Toxicol_23_1890 |
| Author(s) : Xie S , Borazjani A , Hatfield MJ , Edwards CC , Potter PM , Ross MK |
| Ref : Chemical Research in Toxicology , 23 :1890 , 2010 |
| Abstract : Xie_2010_Chem.Res.Toxicol_23_1890 |
| ESTHER : Xie_2010_Chem.Res.Toxicol_23_1890 |
| PubMedSearch : Xie_2010_Chem.Res.Toxicol_23_1890 |
| PubMedID: 21049984 |
| Title : Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug - Barthel_2008_J.Med.Chem_51_298 |
| Author(s) : Barthel BL , Torres RC , Hyatt JL , Edwards CC , Hatfield MJ , Potter PM , Koch TH |
| Ref : Journal of Medicinal Chemistry , 51 :298 , 2008 |
| Abstract : Barthel_2008_J.Med.Chem_51_298 |
| ESTHER : Barthel_2008_J.Med.Chem_51_298 |
| PubMedSearch : Barthel_2008_J.Med.Chem_51_298 |
| PubMedID: 18173233 |
| Title : An improved human carboxylesterase for enzyme\/prodrug therapy with CPT-11 - Wierdl_2008_Cancer.Gene.Ther_15_183 |
| Author(s) : Wierdl M , Tsurkan L , Hyatt JL , Edwards CC , Hatfield MJ , Morton CL , Houghton PJ , Danks MK , Redinbo MR , Potter PM |
| Ref : Cancer Gene Therapy , 15 :183 , 2008 |
| Abstract : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| ESTHER : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedSearch : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedID: 18188187 |
| Title : Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte\/macrophages - Crow_2008_Biochim.Biophys.Acta_1781_643 |
| Author(s) : Crow JA , Middleton BL , Borazjani A , Hatfield MJ , Potter PM , Ross MK |
| Ref : Biochimica & Biophysica Acta , 1781 :643 , 2008 |
| Abstract : Crow_2008_Biochim.Biophys.Acta_1781_643 |
| ESTHER : Crow_2008_Biochim.Biophys.Acta_1781_643 |
| PubMedSearch : Crow_2008_Biochim.Biophys.Acta_1781_643 |
| PubMedID: 18762277 |
| Gene_locus related to this paper: human-CES1 |
| Title : Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1 - Hyatt_2007_J.Med.Chem_50_5727 |
| Author(s) : Hyatt JL , Wadkins RM , Tsurkan L , Hicks LD , Hatfield MJ , Edwards CC , Ross CR, 2nd , Cantalupo SA , Crundwell G , Danks MK , Guy RK , Potter PM |
| Ref : Journal of Medicinal Chemistry , 50 :5727 , 2007 |
| Abstract : Hyatt_2007_J.Med.Chem_50_5727 |
| ESTHER : Hyatt_2007_J.Med.Chem_50_5727 |
| PubMedSearch : Hyatt_2007_J.Med.Chem_50_5727 |
| PubMedID: 17941623 |
| Title : Selective inhibition of carboxylesterases by isatins, indole-2,3-diones - Hyatt_2007_J.Med.Chem_50_1876 |
| Author(s) : Hyatt JL , Moak T , Hatfield MJ , Tsurkan L , Edwards CC , Wierdl M , Danks MK , Wadkins RM , Potter PM |
| Ref : Journal of Medicinal Chemistry , 50 :1876 , 2007 |
| Abstract : Hyatt_2007_J.Med.Chem_50_1876 |
| ESTHER : Hyatt_2007_J.Med.Chem_50_1876 |
| PubMedSearch : Hyatt_2007_J.Med.Chem_50_1876 |
| PubMedID: 17378546 |
| Title : Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy - Yoon_2006_Mol.Cancer.Ther_5_1577 |
| Author(s) : Yoon KJ , Qi J , Remack JS , Virga KG , Hatfield MJ , Potter PM , Lee RE , Danks MK |
| Ref : Mol Cancer Ther , 5 :1577 , 2006 |
| Abstract : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| ESTHER : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedSearch : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedID: 16818517 |