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| Title : Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor gamma Agonists\/Soluble Epoxide Hydrolase Inhibitors - Lillich_2021_J.Med.Chem_64_17259 |
| Author(s) : Lillich FF , Willems S , Ni X , Kilu W , Borkowsky C , Brodsky M , Kramer JS , Brunst S , Hernandez-Olmos V , Heering J , Schierle S , Kestner RI , Mayser FM , Helmstadter M , Gobel T , Weizel L , Namgaladze D , Kaiser A , Steinhilber D , Pfeilschifter W , Kahnt AS , Proschak A , Chaikuad A , Knapp S , Merk D , Proschak E |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Lillich_2021_J.Med.Chem_64_17259 |
| ESTHER : Lillich_2021_J.Med.Chem_64_17259 |
| PubMedSearch : Lillich_2021_J.Med.Chem_64_17259 |
| PubMedID: 34818007 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor gamma - Gobel_2019_Front.Pharmacol_10_263 |
| Author(s) : Gobel T , Diehl O , Heering J , Merk D , Angioni C , Wittmann SK , Buscato E , Kottke R , Weizel L , Schader T , Maier TJ , Geisslinger G , Schubert-Zsilavecz M , Steinhilber D , Proschak E , Kahnt AS |
| Ref : Front Pharmacol , 10 :263 , 2019 |
| Abstract : Gobel_2019_Front.Pharmacol_10_263 |
| ESTHER : Gobel_2019_Front.Pharmacol_10_263 |
| PubMedSearch : Gobel_2019_Front.Pharmacol_10_263 |
| PubMedID: 30949053 |
| Title : N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase\/Peroxisome Proliferator-Activated Receptor gamma Modulators - Blocher_2016_J.Med.Chem_59_61 |
| Author(s) : Blocher R , Lamers C , Wittmann SK , Merk D , Hartmann M , Weizel L , Diehl O , Bruggerhoff A , Boss M , Kaiser A , Schader T , Gobel T , Grundmann M , Angioni C , Heering J , Geisslinger G , Wurglics M , Kostenis E , Brune B , Steinhilber D , Schubert-Zsilavecz M , Kahnt AS , Proschak E |
| Ref : Journal of Medicinal Chemistry , 59 :61 , 2016 |
| Abstract : Blocher_2016_J.Med.Chem_59_61 |
| ESTHER : Blocher_2016_J.Med.Chem_59_61 |
| PubMedSearch : Blocher_2016_J.Med.Chem_59_61 |
| PubMedID: 26595749 |