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Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008 |
Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA |
Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018 |
Abstract : McAllister_2018_J.Med.Chem_61_3008 |
ESTHER : McAllister_2018_J.Med.Chem_61_3008 |
PubMedSearch : McAllister_2018_J.Med.Chem_61_3008 |
PubMedID: 29498843 |
Gene_locus related to this paper: human-MGLL |
Title : Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism - Ahn_2016_ACS.Chem.Biol_11_2529 |
Author(s) : Ahn K , Boehm M , Brown MF , Calloway J , Che Y , Chen J , Fennell KF , Geoghegan KF , Gilbert AM , Gutierrez JA , Kalgutkar AS , Lanba A , Limberakis C , Magee TV , O'Doherty I , Oliver R , Pabst B , Pandit J , Parris K , Pfefferkorn JA , Rolph TP , Patel R , Schuff B , Shanmugasundaram V , Starr JT , Varghese AH , Vera NB , Vernochet C , Yan J |
Ref : ACS Chemical Biology , 11 :2529 , 2016 |
Abstract : Ahn_2016_ACS.Chem.Biol_11_2529 |
ESTHER : Ahn_2016_ACS.Chem.Biol_11_2529 |
PubMedSearch : Ahn_2016_ACS.Chem.Biol_11_2529 |
PubMedID: 27391855 |
Gene_locus related to this paper: human-LYPLAL1 |