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| Title : Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer's Disease - Wang_2024_J.Med.Chem__ |
| Author(s) : Wang L , Sun T , Zhen T , Li W , Yang H , Wang S , Feng F , Chen Y , Sun H |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : Wang_2024_J.Med.Chem__ |
| ESTHER : Wang_2024_J.Med.Chem__ |
| PubMedSearch : Wang_2024_J.Med.Chem__ |
| PubMedID: 38546542 |
| Title : Neuroprotection by tetramethylpyrazine and its synthesized analogues for central nervous system diseases: a review - Feng_2024_Mol.Biol.Rep_51_159 |
| Author(s) : Feng F , Xu DQ , Yue SJ , Chen YY , Tang YP |
| Ref : Mol Biol Rep , 51 :159 , 2024 |
| Abstract : Feng_2024_Mol.Biol.Rep_51_159 |
| ESTHER : Feng_2024_Mol.Biol.Rep_51_159 |
| PubMedSearch : Feng_2024_Mol.Biol.Rep_51_159 |
| PubMedID: 38252346 |
| Title : Optimizing drug-like properties of selective butyrylcholinesterase inhibitors for cognitive improvement: Enhancing aqueous solubility by disrupting molecular plane - Xing_2024_Eur.J.Med.Chem_268_116289 |
| Author(s) : Xing S , Tang X , Wang L , Wang J , Lv B , Wang X , Guo C , Zhao Y , Feng F , Liu W , Chen Y , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 268 :116289 , 2024 |
| Abstract : Xing_2024_Eur.J.Med.Chem_268_116289 |
| ESTHER : Xing_2024_Eur.J.Med.Chem_268_116289 |
| PubMedSearch : Xing_2024_Eur.J.Med.Chem_268_116289 |
| PubMedID: 38452730 |
| Title : N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease - Du_2022_J.Med.Chem__ |
| Author(s) : Du C , Wang L , Guan Q , Yang H , Chen T , Liu Y , Li Q , Lyu W , Lu X , Chen Y , Liu H , Feng F , Liu W , Liu Z , Li W , Sun H |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : Du_2022_J.Med.Chem__ |
| ESTHER : Du_2022_J.Med.Chem__ |
| PubMedSearch : Du_2022_J.Med.Chem__ |
| PubMedID: 35969197 |
| Title : Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease - Wang_2022_Eur.J.Med.Chem_244_114806 |
| Author(s) : Wang Y , Xiong B , Lin H , Li Q , Yang H , Qiao Y , Xu Z , Lyu W , Qu W , Liu W , Chen Y , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 244 :114806 , 2022 |
| Abstract : Wang_2022_Eur.J.Med.Chem_244_114806 |
| ESTHER : Wang_2022_Eur.J.Med.Chem_244_114806 |
| PubMedSearch : Wang_2022_Eur.J.Med.Chem_244_114806 |
| PubMedID: 36223681 |
| Title : A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement - Li_2022_Eur.J.Med.Chem_239_114510 |
| Author(s) : Li Q , Xiong B , Wang Y , Lyu W , Xing S , Chen Y , Liao Q , He S , Feng F , Liu W , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 239 :114510 , 2022 |
| Abstract : Li_2022_Eur.J.Med.Chem_239_114510 |
| ESTHER : Li_2022_Eur.J.Med.Chem_239_114510 |
| PubMedSearch : Li_2022_Eur.J.Med.Chem_239_114510 |
| PubMedID: 35728508 |
| Title : Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease - Lu_2022_Eur.J.Med.Chem_243_114729 |
| Author(s) : Lu X , Qin N , Liu Y , Du C , Feng F , Liu W , Chen Y , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 243 :114729 , 2022 |
| Abstract : Lu_2022_Eur.J.Med.Chem_243_114729 |
| ESTHER : Lu_2022_Eur.J.Med.Chem_243_114729 |
| PubMedSearch : Lu_2022_Eur.J.Med.Chem_243_114729 |
| PubMedID: 36084535 |
| Title : Synthesis and bio-evaluation of a novel selective butyrylcholinesterase inhibitor discovered through structure-based virtual screening - Xing_2021_Int.J.Biol.Macromol_166_1352 |
| Author(s) : Xing S , Chen Y , Xiong B , Lu W , Li Q , Wang Y , Jiao M , Feng F , Liu W , Sun H |
| Ref : Int J Biol Macromol , 166 :1352 , 2021 |
| Abstract : Xing_2021_Int.J.Biol.Macromol_166_1352 |
| ESTHER : Xing_2021_Int.J.Biol.Macromol_166_1352 |
| PubMedSearch : Xing_2021_Int.J.Biol.Macromol_166_1352 |
| PubMedID: 33161083 |
| Title : Structure and therapeutic uses of butyrylcholinesterase: Application in detoxification, Alzheimer's disease, and fat metabolism - Xing_2021_Med.Res.Rev_41_858 |
| Author(s) : Xing S , Li Q , Xiong B , Chen Y , Feng F , Liu W , Sun H |
| Ref : Med Res Rev , 41 :858 , 2021 |
| Abstract : Xing_2021_Med.Res.Rev_41_858 |
| ESTHER : Xing_2021_Med.Res.Rev_41_858 |
| PubMedSearch : Xing_2021_Med.Res.Rev_41_858 |
| PubMedID: 33103262 |
| Title : Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection - Li_2021_J.Med.Chem__ |
| Author(s) : Li Q , Chen Y , Xing S , Liao Q , Xiong B , Wang Y , Lu W , He S , Feng F , Liu W , Sun H |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Li_2021_J.Med.Chem__ |
| ESTHER : Li_2021_J.Med.Chem__ |
| PubMedSearch : Li_2021_J.Med.Chem__ |
| PubMedID: 33973470 |
| Title : Synthesis and activity of miconazole derivatives as dual BChE\/IDO1 inhibitors for the treatment of Alzheimer's disease - Lu_2021_Future.Med.Chem_13_1105 |
| Author(s) : Lu X , Liu Y , Qin N , Yang H , Qiao Y , Jiang X , Chen Y , Feng F , Liu W , Zhou Y , Sun H |
| Ref : Future Med Chem , 13 :1105 , 2021 |
| Abstract : Lu_2021_Future.Med.Chem_13_1105 |
| ESTHER : Lu_2021_Future.Med.Chem_13_1105 |
| PubMedSearch : Lu_2021_Future.Med.Chem_13_1105 |
| PubMedID: 33960203 |
| Title : Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine - Jiang_2021_Eur.J.Med.Chem_223_113663 |
| Author(s) : Jiang X , Liu C , Zou M , Xie H , Lin T , Lyu W , Xu J , Li Y , Feng F , Sun H , Liu W |
| Ref : Eur Journal of Medicinal Chemistry , 223 :113663 , 2021 |
| Abstract : Jiang_2021_Eur.J.Med.Chem_223_113663 |
| ESTHER : Jiang_2021_Eur.J.Med.Chem_223_113663 |
| PubMedSearch : Jiang_2021_Eur.J.Med.Chem_223_113663 |
| PubMedID: 34198150 |
| Title : Discovery of potent glycogen synthase kinase 3\/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease - Jiang_2021_Bioorg.Med.Chem_30_115940 |
| Author(s) : Jiang X , Wang Y , Liu C , Xing C , Lyu W , Wang S , Li Q , Chen T , Chen Y , Feng F , Liu W , Sun H |
| Ref : Bioorganic & Medicinal Chemistry , 30 :115940 , 2021 |
| Abstract : Jiang_2021_Bioorg.Med.Chem_30_115940 |
| ESTHER : Jiang_2021_Bioorg.Med.Chem_30_115940 |
| PubMedSearch : Jiang_2021_Bioorg.Med.Chem_30_115940 |
| PubMedID: 33340937 |
| Title : Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases - Li_2020_Eur.J.Med.Chem_185_111862 |
| Author(s) : Li Q , Xing S , Chen Y , Liao Q , Liu Y , He S , Feng F , Zhang J , Liu W , Guo Q , Sun Y , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 185 :111862 , 2020 |
| Abstract : Li_2020_Eur.J.Med.Chem_185_111862 |
| ESTHER : Li_2020_Eur.J.Med.Chem_185_111862 |
| PubMedSearch : Li_2020_Eur.J.Med.Chem_185_111862 |
| PubMedID: 31735576 |
| Title : Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease - Mo_2020_J.Enzyme.Inhib.Med.Chem_35_330 |
| Author(s) : Mo J , Chen T , Yang H , Guo Y , Li Q , Qiao Y , Lin H , Feng F , Liu W , Chen Y , Liu Z , Sun H |
| Ref : J Enzyme Inhib Med Chem , 35 :330 , 2020 |
| Abstract : Mo_2020_J.Enzyme.Inhib.Med.Chem_35_330 |
| ESTHER : Mo_2020_J.Enzyme.Inhib.Med.Chem_35_330 |
| PubMedSearch : Mo_2020_J.Enzyme.Inhib.Med.Chem_35_330 |
| PubMedID: 31856607 |
| Title : Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer's disease - Liao_2020_Bioorg.Chem_99_103844 |
| Author(s) : Liao Q , Li Q , Zhao Y , Jiang P , Yan Y , Sun H , Liu W , Feng F , Qu W |
| Ref : Bioorg Chem , 99 :103844 , 2020 |
| Abstract : Liao_2020_Bioorg.Chem_99_103844 |
| ESTHER : Liao_2020_Bioorg.Chem_99_103844 |
| PubMedSearch : Liao_2020_Bioorg.Chem_99_103844 |
| PubMedID: 32325336 |
| Title : Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor - Li_2020_J.Med.Chem_63_10030 |
| Author(s) : Li Q , Xing S , Chen Y , Liao Q , Xiong B , He S , Lu W , Liu Y , Yang H , Feng F , Liu W , Sun H |
| Ref : Journal of Medicinal Chemistry , 63 :10030 , 2020 |
| Abstract : Li_2020_J.Med.Chem_63_10030 |
| ESTHER : Li_2020_J.Med.Chem_63_10030 |
| PubMedSearch : Li_2020_J.Med.Chem_63_10030 |
| PubMedID: 32787113 |
| Title : Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease - Jiang_2020_Eur.J.Med.Chem_207_112751 |
| Author(s) : Jiang X , Zhou J , Wang Y , Chen L , Duan Y , Huang J , Liu C , Chen Y , Liu W , Sun H , Feng F , Qu W |
| Ref : Eur Journal of Medicinal Chemistry , 207 :112751 , 2020 |
| Abstract : Jiang_2020_Eur.J.Med.Chem_207_112751 |
| ESTHER : Jiang_2020_Eur.J.Med.Chem_207_112751 |
| PubMedSearch : Jiang_2020_Eur.J.Med.Chem_207_112751 |
| PubMedID: 32950908 |
| Title : Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening - Yang_2019_Bioorg.Chem_92_103294 |
| Author(s) : Yang H , Du C , Li Q , Chen T , Lu X , Feng F , Chen Y , Liu W , Sun H |
| Ref : Bioorg Chem , 92 :103294 , 2019 |
| Abstract : Yang_2019_Bioorg.Chem_92_103294 |
| ESTHER : Yang_2019_Bioorg.Chem_92_103294 |
| PubMedSearch : Yang_2019_Bioorg.Chem_92_103294 |
| PubMedID: 31557623 |
| Title : Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo - Guo_2019_Bioorg.Chem_92_103258 |
| Author(s) : Guo E , Hu Y , Du T , Zhu H , Chen L , Qu W , Zhang J , Xie N , Liu W , Feng F , Xu J |
| Ref : Bioorg Chem , 92 :103258 , 2019 |
| Abstract : Guo_2019_Bioorg.Chem_92_103258 |
| ESTHER : Guo_2019_Bioorg.Chem_92_103258 |
| PubMedSearch : Guo_2019_Bioorg.Chem_92_103258 |
| PubMedID: 31520892 |
| Title : Design, synthesis, biological evaluation, and molecular modeling studies of quinoline-ferulic acid hybrids as cholinesterase inhibitors - Mo_2019_Bioorg.Chem_93_103310 |
| Author(s) : Mo J , Yang H , Chen T , Li Q , Lin H , Feng F , Liu W , Qu W , Guo Q , Chi H , Chen Y , Sun H |
| Ref : Bioorg Chem , 93 :103310 , 2019 |
| Abstract : Mo_2019_Bioorg.Chem_93_103310 |
| ESTHER : Mo_2019_Bioorg.Chem_93_103310 |
| PubMedSearch : Mo_2019_Bioorg.Chem_93_103310 |
| PubMedID: 31586704 |
| Title : Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation - Lu_2019_Bioorg.Chem_85_117 |
| Author(s) : Lu X , Yang H , Li Q , Chen Y , Zhou Y , Feng F , Liu W , Guo Q , Sun H |
| Ref : Bioorg Chem , 85 :117 , 2018 || 2019 |
| Abstract : Lu_2019_Bioorg.Chem_85_117 |
| ESTHER : Lu_2019_Bioorg.Chem_85_117 |
| PubMedSearch : Lu_2019_Bioorg.Chem_85_117 |
| PubMedID: 30605885 |
| Title : Dual GSK-3beta\/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery - Jiang_2018_ACS.Med.Chem.Lett_9_171 |
| Author(s) : Jiang XY , Chen TK , Zhou JT , He SY , Yang HY , Chen Y , Qu W , Feng F , Sun HP |
| Ref : ACS Med Chem Lett , 9 :171 , 2018 |
| Abstract : Jiang_2018_ACS.Med.Chem.Lett_9_171 |
| ESTHER : Jiang_2018_ACS.Med.Chem.Lett_9_171 |
| PubMedSearch : Jiang_2018_ACS.Med.Chem.Lett_9_171 |
| PubMedID: 29541355 |
| Title : Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease - Li_2018_Eur.J.Med.Chem_158_463 |
| Author(s) : Li Q , He S , Chen Y , Feng F , Qu W , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 158 :463 , 2018 |
| Abstract : Li_2018_Eur.J.Med.Chem_158_463 |
| ESTHER : Li_2018_Eur.J.Med.Chem_158_463 |
| PubMedSearch : Li_2018_Eur.J.Med.Chem_158_463 |
| PubMedID: 30243151 |
| Title : Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease - Lu_2018_Bioorg.Med.Chem_26_1665 |
| Author(s) : Lu X , He SY , Li Q , Yang H , Jiang X , Lin H , Chen Y , Qu W , Feng F , Bian Y , Zhou Y , Sun H |
| Ref : Bioorganic & Medicinal Chemistry , 26 :1665 , 2018 |
| Abstract : Lu_2018_Bioorg.Med.Chem_26_1665 |
| ESTHER : Lu_2018_Bioorg.Med.Chem_26_1665 |
| PubMedSearch : Lu_2018_Bioorg.Med.Chem_26_1665 |
| PubMedID: 29475581 |
| Title : Pentapeptide Prosequence Enhances Expression and Structure Folding of Recombinant Thermomyces lanuginosus Lipase in Pichia pastoris - Cai_2017_Protein.Pept.Lett_24_676 |
| Author(s) : Cai H , Zhao M , Li Y , Mao J , Cai C , Feng F |
| Ref : Protein Pept Lett , 24 :676 , 2017 |
| Abstract : Cai_2017_Protein.Pept.Lett_24_676 |
| ESTHER : Cai_2017_Protein.Pept.Lett_24_676 |
| PubMedSearch : Cai_2017_Protein.Pept.Lett_24_676 |
| PubMedID: 28641563 |