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Author Report for: Du H

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    Title: LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer
    Zhao T, Liu S, Hanna NH, Jalal S, Ding X, Wan J, Yan C, Du H
    Ref: J Immunother Cancer, 11:, 2023 : PubMed


    Title: The Interaction Between Two Metabolites of Polygala Tenuifolia and Cholinesterases
    Gao C, Du H
    Ref: Protein Pept Lett, :, 2022 : PubMed


    Title: Therapeutic efficacy of rscAAVrh74.miniCMV.LIPA gene therapy in a mouse model of lysosomal acid lipase deficiency
    Lam P, Ashbrook A, Zygmunt DA, Yan C, Du H, Martin PT
    Ref: Mol Ther Methods Clin Dev, 26:413, 2022 : PubMed


    Title: Identification of closely associated SNPs and candidate genes with seed size and shape via deep re-sequencing GWAS in soybean
    Shao Z, Shao J, Huo X, Li W, Kong Y, Du H, Li X, Zhang C
    Ref: Theor Appl Genet, :, 2022 : PubMed


    Title: Analysis of the binding selectivity and inhibiting mechanism of chlorogenic acid isomers and their interaction with grass carp endogenous lipase using multi-spectroscopic, inhibition kinetics and modeling methods
    Xu Z, Cao Q, Manyande A, Xiong S, Du H
    Ref: Food Chem, 382:132106, 2022 : PubMed


    Title: Lysosomal acid lipase, CSF1R and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells
    Zhao T, Liu S, Ding X, Johnson EM, Hanna NH, Singh K, Sen CK, Wan J, Du H, Yan C
    Ref: JCI Insight, :, 2022 : PubMed


    Title: Lysosomal Acid Lipase Deficiency Controls T- and B-Regulatory Cell Homeostasis in the Lymph Nodes of Mice with Human Cancer Xenotransplants
    Ding X, Zhao T, Lee CC, Yan C, Du H
    Ref: American Journal of Pathology, 191:353, 2021 : PubMed


    Title: Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation
    Du H, Jiang X, Ma M, Xu H, Liu S, Ma F
    Ref: Bioorganic & Medicinal Chemistry Lett, :127659, 2020 : PubMed


    Title: Mechanistic insight into esterase-catalyzed hydrolysis of phthalate esters (PAEs) based on integrated multi-spectroscopic analyses and docking simulation
    Du H, Hu RW, Zhao HM, Huang HB, Xiang L, Liu BL, Feng NX, Li H, Li YW and Mo CH <1 more author(s)>
    Ref: J Hazard Mater, 408:124901, 2020 : PubMed


    Title: Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease
    Nguyen HD, Ticer T, Bastian D, Kuril S, Li H, Du H, Yan C, Yu XZ
    Ref: Cell Rep, 33:108316, 2020 : PubMed


    Title: Bioaugmentation of Exogenous Strain Rhodococcus sp. 2G Can Efficiently Mitigate Di(2-ethylhexyl) Phthalate Contamination to Vegetable Cultivation
    Zhao HM, Du H, Huang CQ, Li S, Zeng XH, Huang XJ, Xiang L, Li H, Li YW and He Z <2 more author(s)>
    Ref: Journal of Agricultural and Food Chemistry, 67:6940, 2019 : PubMed


    Title: Study of the interactions of forsythiaside and rutin with acetylcholinesterase (AChE)
    Yan X, Chen T, Zhang L, Du H
    Ref: Int J Biol Macromol, 119:1344, 2018 : PubMed


    Title: Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation
    Ma F, Du H
    Ref: Eur Journal of Medicinal Chemistry, 140:118, 2017 : PubMed


    Title: Lysosome-mediated degradation of a distinct pool of lipid droplets during hepatic stellate cell activation
    Tuohetahuntila M, Molenaar MR, Spee B, Brouwers JF, Wubbolts R, Houweling M, Yan C, Du H, VanderVen BC and Helms JB <1 more author(s)>
    Ref: Journal of Biological Chemistry, 292:12436, 2017 : PubMed


    Title: A new method to characterize the kinetics of cholinesterases inhibited by carbamates
    Xiao Q, Zhou H, Wei H, Du H, Tan W, Zhan Y, Pistolozzi M
    Ref: J Pharm Biomed Anal, 144:175, 2017 : PubMed


    Title: Protective effects of Forsythoside A on amyloid beta-induced apoptosis in PC12 cells by downregulating acetylcholinesterase
    Yan X, Chen T, Zhang L, Du H
    Ref: European Journal of Pharmacology, 810:141, 2017 : PubMed


    Title: Endothelial Rab7 GTPase mediates tumor growth and metastasis in lysosomal acid lipase-deficient mice
    Zhao T, Ding X, Yan C, Du H
    Ref: Journal of Biological Chemistry, 292:19198, 2017 : PubMed


    Title: Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
    Grumet L, Eichmann TO, Taschler U, Zierler KA, Leopold C, Moustafa T, Radovic B, Romauch M, Yan C and Lass A <6 more author(s)>
    Ref: Journal of Biological Chemistry, 291:17977, 2016 : PubMed


    Title: A New Flavonoid Glycoside from Lysionotus pauciflorus
    Luo W, Wen Y, Tu Y, Du H, Li Q, Zhu C, Li Y
    Ref: Nat Prod Commun, 11:621, 2016 : PubMed


    Title: Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice
    Radovic B, Vujic N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J and Kratky D <12 more author(s)>
    Ref: Diabetologia, 59:1743, 2016 : PubMed


    Title: Hepatocyte-Specific Expression of Human Lysosome Acid Lipase Corrects Liver Inflammation and Tumor Metastasis in lal(-/-) Mice
    Du H, Zhao T, Ding X, Yan C
    Ref: American Journal of Pathology, 185:2379, 2015 : PubMed


    Title: Stereoselective inhibition of human butyrylcholinesterase by the enantiomers of bambuterol and their intermediates
    Pistolozzi M, Du H, Wei H, Tan W
    Ref: Drug Metabolism & Disposition: The Biological Fate of Chemicals, 43:344, 2015 : PubMed


    Title: Anticholinesterases and antioxidant alkamides from Piper nigrum fruits
    Tu Y, Zhong Y, Du H, Luo W, Wen Y, Li Q, Zhu C, Li Y
    Ref: Nat Prod Res, :1, 2015 : PubMed


    Title: Abundance and significance of neuroligin-1 and glutamate in Hirschsprung's disease
    Wang J, Du H, Mou YR, Niu JY, Zhang WT, Yang HC, Li AW
    Ref: World J Gastroenterol, 21:7172, 2015 : PubMed


    Title: High quality draft genomic sequence of Flavobacterium enshiense DK69(T) and comparison among Flavobacterium genomes
    Zeng Z, Chen C, Du H, Wang G, Li M
    Ref: Stand Genomic Sci, 10:92, 2015 : PubMed


    Title: Reversal of advanced disease in lysosomal acid lipase deficient mice: a model for lysosomal acid lipase deficiency disease
    Sun Y, Xu YH, Du H, Quinn B, Liou B, Stanton L, Inskeep V, Ran H, Jakubowitz P and Grabowski GA <1 more author(s)>
    Ref: Mol Genet Metab, 112:229, 2014 : PubMed


    Title: Neuregulin-1 impairs the long-term depression of hippocampal inhibitory synapses by facilitating the degradation of endocannabinoid 2-AG
    Du H, Kwon IK, Kim J
    Ref: Journal of Neuroscience, 33:15022, 2013 : PubMed


    Title: Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice
    Yan C, Ding X, Dasgupta N, Wu L, Du H
    Ref: PLoS ONE, 7:e30701, 2012 : PubMed


    Title: Lysosomal acid lipase deficiency impairs regulation of ABCA1 gene and formation of high density lipoproteins in cholesteryl ester storage disease
    Bowden KL, Bilbey NJ, Bilawchuk LM, Boadu E, Sidhu R, Ory DS, Du H, Chan T, Francis GA
    Ref: Journal of Biological Chemistry, 286:30624, 2011 : PubMed


    Title: Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques
    Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y and Wang X <32 more author(s)>
    Ref: Nat Biotechnol, 29:1019, 2011 : PubMed


    Title: Critical roles of lysosomal acid lipase in myelopoiesis
    Qu P, Shelley WC, Yoder MC, Wu L, Du H, Yan C
    Ref: American Journal of Pathology, 176:2394, 2010 : PubMed


    Title: Critical roles of lysosomal acid lipase in T cell development and function
    Qu P, Du H, Wilkes DS, Yan C
    Ref: American Journal of Pathology, 174:944, 2009 : PubMed


    Title: Chemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors
    Rosenbaum AI, Rujoi M, Huang AY, Du H, Grabowski GA, Maxfield FR
    Ref: Biochimica & Biophysica Acta, 1791:1155, 2009 : PubMed


    Title: Clinical, experimental, and genomic differences between intermediately pathogenic, highly pathogenic, and epidemic Streptococcus suis
    Ye C, Zheng H, Zhang J, Jing H, Wang L, Xiong Y, Wang W, Zhou Z, Sun Q and Xu J <3 more author(s)>
    Ref: J Infect Dis, 199:97, 2009 : PubMed


    Title: Wolman disease/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice
    Du H, Cameron TL, Garger SJ, Pogue GP, Hamm LA, White E, Hanley KM, Grabowski GA
    Ref: J Lipid Res, 49:1646, 2008 : PubMed


    Title: Effects of 3-benzidino-6-phenylpyridazine, as an acetylcholinesterase inhibitor, on outward potassium current in acutely isolated rat hippocampal pyramidal neurons
    Du H, Li M, Yang P
    Ref: Toxicol Lett, 181:104, 2008 : PubMed


    Title: Lysosomal acid lipase over-expression disrupts lamellar body genesis and alveolar structure in the lung
    Li Y, Qin Y, Li H, Wu R, Yan C, Du H
    Ref: International Journal of Experimental Pathology, 88:427, 2007 : PubMed


    Title: Gene delivery by the hSP-B promoter to lung alveolar type II epithelial cells in LAL-knockout mice through bone marrow mesenchymal stem cells
    Yan C, Lian X, Dai Y, Wang X, Qu P, White A, Qin Y, Du H
    Ref: Gene Therapy, 14:1461, 2007 : PubMed


    Title: Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice
    Yan C, Lian X, Li Y, Dai Y, White A, Qin Y, Li H, Hume DA, Du H
    Ref: American Journal of Pathology, 169:916, 2006 : PubMed


    Title: MRI of fat distribution in a mouse model of lysosomal acid lipase deficiency
    Du H, Dardzinski BJ, O'Brien KJ, Donnelly LF
    Ref: AJR Am J Roentgenol, 184:658, 2005 : PubMed


    Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4
    Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K and Wilson RK <111 more author(s)>
    Ref: Nature, 434:724, 2005 : PubMed


    Title: Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice
    Lian X, Yan C, Qin Y, Knox L, Li T, Du H
    Ref: American Journal of Pathology, 167:813, 2005 : PubMed


    Title: Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung
    Lian X, Yan C, Yang L, Xu Y, Du H
    Ref: American Journal of Physiology Lung Cell Mol Physiol, 286:L801, 2004 : PubMed


    Title: The DNA sequence of human chromosome 7
    Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S and Wilson RK <97 more author(s)>
    Ref: Nature, 424:157, 2003 : PubMed


    Title: The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes
    Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, Cordum HS, Hillier L, Brown LG, Repping S, Pyntikova T, Ali J and Page DC <30 more author(s)>
    Ref: Nature, 423:825, 2003 : PubMed


    Title: Lysosomal Acid lipase deficiency: correction of lipid storage by adenovirus-mediated gene transfer in mice
    Du H, Heur M, Witte DP, Ameis D, Grabowski GA
    Ref: Hum Gene Therapy, 13:1361, 2002 : PubMed


    Title: Enzyme therapy for lysosomal acid lipase deficiency in the mouse
    Du H, Schiavi S, Levine M, Mishra J, Heur M, Grabowski GA
    Ref: Hum Mol Genet, 10:1639, 2001 : PubMed


    Title: Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span
    Du H, Heur M, Duanmu M, Grabowski GA, Hui DY, Witte DP, Mishra J
    Ref: J Lipid Res, 42:489, 2001 : PubMed


    Title: Phenotypic correction of lipid storage and growth arrest in wolman disease fibroblasts by gene transfer of lysosomal acid lipase
    Tietge UJ, Sun G, Czarnecki S, Yu Q, Lohse P, Du H, Grabowski GA, Glick JM, Rader DJ
    Ref: Hum Gene Therapy, 12:279, 2001 : PubMed


    Title: Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana
    Tabata S, Kaneko T, Nakamura Y, Kotani H, Kato T, Asamizu E, Miyajima N, Sasamoto S, Kimura T and Fransz P <119 more author(s)>
    Ref: Nature, 408:823, 2000 : PubMed


    Title: Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which ldl-cholesteryl ester hydrolysis exceeds ldl protein degradation
    Buton X, Mamdouh Z, Ghosh R, Du H, Kuriakose G, Beatini N, Grabowski GA, Maxfield FR, Tabas I
    Ref: Journal of Biological Chemistry, 274:32112, 1999 : PubMed


    Title: Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana
    Mayer K, Schuller C, Wambutt R, Murphy G, Volckaert G, Pohl T, Dusterhoft A, Stiekema W, Entian KD and McCombie WR <220 more author(s)>
    Ref: Nature, 402:769, 1999 : PubMed


    Title: Mouse lysosomal acid lipase: characterization of the gene and analysis of promoter activity
    Du H, Duanmu M, Rosa LR
    Ref: Gene, 208:285, 1998 : PubMed


    Title: Molecular and enzymatic analyses of lysosomal acid lipase in cholesteryl ester storage disease
    Du H, Sheriff S, Bezerra J, Leonova T, Grabowski GA
    Ref: Mol Genet Metab, 64:126, 1998 : PubMed


    Title: Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage
    Du H, Duanmu M, Witte D, Grabowski GA
    Ref: Hum Mol Genet, 7:1347, 1998 : PubMed


    Title: Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein
    Du H, Witte DP, Grabowski GA
    Ref: J Lipid Res, 37:937, 1996 : PubMed


    Title: Characterization of lysosomal acid lipase by site-directed mutagenesis and heterologous expression
    Sheriff S, Du H, Grabowski GA
    Ref: Journal of Biological Chemistry, 270:27766, 1995 : PubMed


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