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Author Report for: Donnelly-Roberts D

Contact information:

Donnelly-Roberts Diana L
Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064-6100
USA
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    Title: Nicotinic acetylcholine receptors as therapeutic targets: Emerging frontiers in basic research and clinical science--Editorial Comments
    Dani JA, Donnelly-Roberts D, Bertrand D
    Ref: Biochemical Pharmacology, 97:351, 2015 : PubMed

            

    Title: Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with alpha7 nicotinic acetylcholine receptor agonists
    Minami SS, Shen V, Le D, Krabbe G, Asgarov R, Perez-Celajes L, Lee CH, Li J, Donnelly-Roberts D, Gan L
    Ref: Biochemical Pharmacology, 97:454, 2015 : PubMed

            

    Title: Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--editorial comments
    Dani JA, Donnelly-Roberts D, Bertrand D
    Ref: Biochemical Pharmacology, 86:1041, 2013 : PubMed

            

    Title: Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca(2)(+) channel blockers with analgesic activity
    Beebe X, Darczak D, Henry RF, Vortherms T, Janis R, Namovic M, Donnelly-Roberts D, Kage KL, Surowy C and Scott VE <14 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 20:4128, 2012 : PubMed

            

    Title: High throughput functional assays for P2X receptors
    Namovic MT, Jarvis MF, Donnelly-Roberts D
    Ref: Curr Protoc Pharmacol, Chapter 9:Unit 9 15, 2012 : PubMed

            

    Title: Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--Editorial Comments
    Donnelly-Roberts D, Bertrand D, Gopalakrishnan M
    Ref: Biochemical Pharmacology, 82:797, 2011 : PubMed

            

    Title: Poster: A-582941, a pro-cognitive alpha7 nAChR agonist, differentially modulates mitochondrial membrane potential
    Namovic M, Hu M, Abraham V, Towne D, Lee C-H, Gopalakrishnan M, Esbenshade T, Donnelly-Roberts D
    Ref: Biochemical Pharmacology, 82:1027, 2011 : PubMed

            

    Title: Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists
    Perez-Medrano A, Donnelly-Roberts D, Florjancic AS, Nelson DW, Li T, Namovic MT, Peddi S, Faltynek CR, Jarvis MF, Carroll WA
    Ref: Bioorganic & Medicinal Chemistry Lett, 21:3297, 2011 : PubMed

            

    Title: Comparative analysis of inactivated-state block of N-type (Ca(v)2.2) calcium channels
    Vortherms TA, Swensen AM, Niforatos W, Limberis JT, Neelands TR, Janis RS, Thimmapaya R, Donnelly-Roberts D, Namovic MT and Scott VE <5 more author(s)>
    Ref: Inflamm Res, 60:683, 2011 : PubMed

            

    Title: Poster: Radioligand binding characterization of [3H]-A-998679: A novel positive allosteric modulator of alpha4/beta2 nAChRs
    Anderson DJ, Vaidyanathan S, Namovic M, Donnelly-Roberts D, Lee L, Gopalakrishnan M
    Ref: Biochemical Pharmacology, 78:903, 2009 : PubMed

            

    Title: Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--editorial perspective
    Bertrand D, Gopalakrishnan M, Donnelly-Roberts D
    Ref: Biochemical Pharmacology, 78:657, 2009 : PubMed

            

    Title: Selective P2X(7) receptor antagonists for chronic inflammation and pain
    Carroll WA, Donnelly-Roberts D, Jarvis MF
    Ref: Purinergic Signal, 5:63, 2009 : PubMed

            

    Title: Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors
    Donnelly-Roberts D, Namovic MT, Han P, Jarvis MF
    Ref: British Journal of Pharmacology, 157:1203, 2009 : PubMed

            

    Title: [3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors
    Donnelly-Roberts D, Namovic MT, Surber B, Vaidyanathan SX, Perez-Medrano A, Wang Y, Carroll WA, Jarvis MF
    Ref: Neuropharmacology, 56:223, 2009 : PubMed

            

    Title: Poster: Profile of A-716096, a novel thiazolylidine positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor
    Donnelly-Roberts D, Malysz J, Faghih R, Gronlien H, Haakerud M, Thorin-Hagne K, Ween H, Gopalakrishnan SM, Hu M and Gopalakrishnan M <9 more author(s)>
    Ref: Biochemical Pharmacology, 78:912, 2009 : PubMed

            

    Title: The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1alphabeta knockout mice
    Honore P, Donnelly-Roberts D, Namovic M, Zhong C, Wade C, Chandran P, Zhu C, Carroll W, Perez-Medrano A and Jarvis MF <1 more author(s)>
    Ref: Behavioural Brain Research, 204:77, 2009 : PubMed

            

    Title: Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain
    Perez-Medrano A, Donnelly-Roberts D, Honore P, Hsieh GC, Namovic MT, Peddi S, Shuai Q, Wang Y, Faltynek CR and Carroll WA <1 more author(s)>
    Ref: Journal of Medicinal Chemistry, 52:3366, 2009 : PubMed

            

    Title: Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists
    Betschmann P, Bettencourt B, Donnelly-Roberts D, Friedman M, George J, Hirst G, Josephsohn N, Konopacki D, Li B and Woller K <8 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:3848, 2008 : PubMed

            

    Title: Painful purinergic receptors
    Donnelly-Roberts D, McGaraughty S, Shieh CC, Honore P, Jarvis MF
    Ref: Journal of Pharmacology & Experimental Therapeutics, 324:409, 2008 : PubMed

            

    Title: Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists
    Florjancic AS, Peddi S, Perez-Medrano A, Li B, Namovic MT, Grayson G, Donnelly-Roberts D, Jarvis MF, Carroll WA
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:2089, 2008 : PubMed

            

    Title: Synthesis and in vitro activity of N'-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists
    Morytko MJ, Betschmann P, Woller K, Ericsson A, Chen H, Donnelly-Roberts D, Namovic MT, Jarvis MF, Carroll WA, Rafferty P
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:2093, 2008 : PubMed

            

    Title: Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists
    Nelson DW, Sarris K, Kalvin DM, Namovic MT, Grayson G, Donnelly-Roberts D, Harris R, Honore P, Jarvis MF and Carroll WA <1 more author(s)>
    Ref: Journal of Medicinal Chemistry, 51:3030, 2008 : PubMed

            

    Title: Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists
    Carroll WA, Kalvin DM, Perez Medrano A, Florjancic AS, Wang Y, Donnelly-Roberts D, Namovic MT, Grayson G, Honore P, Jarvis MF
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:4044, 2007 : PubMed

            

    Title: Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states
    Donnelly-Roberts D, Jarvis MF
    Ref: British Journal of Pharmacology, 151:571, 2007 : PubMed

            

    Title: P2X7-related modulation of pathological nociception in rats
    McGaraughty S, Chu KL, Namovic MT, Donnelly-Roberts D, Harris RR, Zhang XF, Shieh CC, Wismer CT, Zhu CZ and Jarvis MF <9 more author(s)>
    Ref: Neuroscience, 146:1817, 2007 : PubMed

            

    Title: A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat
    Honore P, Donnelly-Roberts D, Namovic MT, Hsieh G, Zhu CZ, Mikusa JP, Hernandez G, Zhong C, Gauvin DM and Jarvis MF <7 more author(s)>
    Ref: Journal of Pharmacology & Experimental Therapeutics, 319:1376, 2006 : PubMed

            

    Title: 1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction
    Kolasa T, Matulenko MA, Hakeem AA, Patel MV, Mortell K, Bhatia P, Henry R, Nakane M, Hsieh GC and Stewart AO <13 more author(s)>
    Ref: Journal of Medicinal Chemistry, 49:5093, 2006 : PubMed

            

    Title: Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists
    Nelson DW, Gregg RJ, Kort ME, Perez-Medrano A, Voight EA, Wang Y, Grayson G, Namovic MT, Donnelly-Roberts D and Carroll WA <4 more author(s)>
    Ref: Journal of Medicinal Chemistry, 49:3659, 2006 : PubMed

            

    Title: Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzam ide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction
    Patel MV, Kolasa T, Mortell K, Matulenko MA, Hakeem AA, Rohde JJ, Nelson SL, Cowart MD, Nakane M and Stewart AO <18 more author(s)>
    Ref: Journal of Medicinal Chemistry, 49:7450, 2006 : PubMed

            

    Title: A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor
    Rueter LE, Donnelly-Roberts D, Curzon P, Briggs CA, Anderson DJ, Bitner RS
    Ref: CNS Drug Rev, 12:100, 2006 : PubMed

            

    Title: Pharmacological characterization of P2X7 receptors in rat peritoneal cells
    Chen YW, Donnelly-Roberts D, Namovic MT, Gintant GA, Cox BF, Jarvis MF, Harris RR
    Ref: Inflamm Res, 54:119, 2005 : PubMed

            

    Title: 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist
    Nakane M, Cowart MD, Hsieh GC, Miller L, Uchic ME, Chang R, Terranova MA, Donnelly-Roberts D, Namovic MT and Moreland RB <5 more author(s)>
    Ref: Neuropharmacology, 49:112, 2005 : PubMed

            

    Title: In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide
    Adams MR, Nikkel AL, Donnelly-Roberts D, Watt AT, Johnston JF, Cowsert LM, Butler M, Kroeger PE, Frost L and Bitner RS <2 more author(s)>
    Ref: Brain Research Mol Brain Res, 129:67, 2004 : PubMed

            

    Title: Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats
    Brioni JD, Moreland RB, Cowart M, Hsieh GC, Stewart AO, Hedlund P, Donnelly-Roberts D, Nakane M, Lynch JJ, 3rd and Sullivan JP <5 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 101:6758, 2004 : PubMed

            

    Title: Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction
    Cowart M, Latshaw SP, Bhatia P, Daanen JF, Rohde J, Nelson SL, Patel M, Kolasa T, Nakane M and Stewart AO <13 more author(s)>
    Ref: Journal of Medicinal Chemistry, 47:3853, 2004 : PubMed

            

    Title: Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells
    Donnelly-Roberts D, Namovic MT, Faltynek CR, Jarvis MF
    Ref: Journal of Pharmacology & Experimental Therapeutics, 308:1053, 2004 : PubMed

            

    Title: Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine
    Hsieh GC, Hollingsworth PR, Martino B, Chang R, Terranova MA, O'Neill AB, Lynch JJ, Moreland RB, Donnelly-Roberts D and Brioni JD <5 more author(s)>
    Ref: Journal of Pharmacology & Experimental Therapeutics, 308:330, 2004 : PubMed

            

    Title: Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists
    Matulenko MA, Hakeem AA, Kolasa T, Nakane M, Terranova MA, Uchic ME, Miller LN, Chang R, Donnelly-Roberts D and Stewart AO <3 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 12:3471, 2004 : PubMed

            

    Title: Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand
    Matulenko MA, Surber B, Fan L, Kolasa T, Nakane M, Terranova MA, Uchic ME, Miller LN, Chang R and Stewart AO <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 14:5095, 2004 : PubMed

            

    Title: Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5)
    Moreland RB, Nakane M, Donnelly-Roberts D, Miller LN, Chang R, Uchic ME, Terranova MA, Gubbins EJ, Helfrich RJ and Brioni JD <3 more author(s)>
    Ref: Biochemical Pharmacology, 68:761, 2004 : PubMed

            

    Title: ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders
    Rueter LE, Anderson DJ, Briggs CA, Donnelly-Roberts D, Gintant GA, Gopalakrishnan M, Lin NH, Osinski MA, Reinhart GA and Sullivan JP <8 more author(s)>
    Ref: CNS Drug Rev, 10:167, 2004 : PubMed

            

    Title: Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning
    Stewart AO, Cowart MD, Moreland RB, Latshaw SP, Matulenko MA, Bhatia PA, Wang X, Daanen JF, Nelson SL and Brioni JD <6 more author(s)>
    Ref: Journal of Medicinal Chemistry, 47:2348, 2004 : PubMed

            

    Title: A cell-based microarrayed compound screening format for identifying agonists of G-protein-coupled receptors
    Gopalakrishnan SM, Moreland RB, Kofron JL, Helfrich RJ, Gubbins E, McGowen J, Masters JN, Donnelly-Roberts D, Brioni JD and Warrior U <1 more author(s)>
    Ref: Analytical Biochemistry, 321:192, 2003 : PubMed

            

    Title: Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat
    Bitner RS, Nikkel AL, Curzon P, Donnelly-Roberts D, Puttfarcken PS, Namovic M, Jacobs IC, Meyer MD, Decker MW
    Ref: Brain Research, 871:66, 2000 : PubMed

            

    Title: Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors
    Bannon AW, Decker MW, Holladay MW, Curzon P, Donnelly-Roberts D, Puttfarcken PS, Bitner RS, Diaz A, Dickenson AH and Arneric SP <2 more author(s)>
    Ref: Science, 279:77, 1998 : PubMed

            

    Title: The role of neuronal nicotinic acetylcholine receptors in antinociception: effects of ABT-594
    Decker MW, Curzon P, Holladay MW, Nikkel AL, Bitner RS, Bannon AW, Donnelly-Roberts D, Puttfarcken PS, Kuntzweiler TA and Arneric SP <2 more author(s)>
    Ref: Journal de Physiologie (Paris), 92:221, 1998 : PubMed

            

    Title: ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization
    Donnelly-Roberts D, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT and Arneric SP <2 more author(s)>
    Ref: Journal of Pharmacology & Experimental Therapeutics, 285:777, 1998 : PubMed

            

    Title: Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice
    Holladay MW, Bai H, Li Y, Lin NH, Daanen JF, Ryther KB, Wasicak JT, Kincaid JF, He Y and Arneric SP <12 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 8:2797, 1998 : PubMed

            

    Title: Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors
    Holladay MW, Wasicak JT, Lin NH, He Y, Ryther KB, Bannon AW, Buckley MJ, Kim DJ, Decker MW and Arneric SP <7 more author(s)>
    Ref: Journal of Medicinal Chemistry, 41:407, 1998 : PubMed

            

    Title: Synthesis and structure-activity relationships of pyridine-modified analogs of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543, a potent nicotinic acetylcholine receptor agonist
    Lin NH, Gunn DE, Li Y, He Y, Bai H, Ryther KB, Kuntzweiler T, Donnelly-Roberts D, Anderson DJ and Holladay MW <3 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 8:249, 1998 : PubMed

            

    Title: Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo
    Briggs CA, Anderson DJ, Brioni JD, Buccafusco JJ, Buckley MJ, Campbell JE, Decker MW, Donnelly-Roberts D, Elliott RL and Arneric SP <10 more author(s)>
    Ref: Pharmacol Biochem Behav, 57:231, 1997 : PubMed

            

    Title: Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties
    Lin NH, Gunn DE, Ryther KB, Garvey DS, Donnelly-Roberts D, Decker MW, Brioni JD, Buckley MJ, Rodrigues AD and Holladay MW <7 more author(s)>
    Ref: Journal of Medicinal Chemistry, 40:385, 1997 : PubMed

            

    Title: Evidence for nicotinic receptors potentially modulating nociceptive transmission at the level of the primary sensory neuron: studies with F11 cells
    Puttfarcken PS, Manelli AM, Arneric SP, Donnelly-Roberts D
    Ref: Journal of Neurochemistry, 69:930, 1997 : PubMed

            

    Title: ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties
    Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Xue IC, Piattoni-Kaplan M, Molinari E, Campbell JE and Arneric SP <8 more author(s)>
    Ref: Journal of Pharmacology & Experimental Therapeutics, 283:235, 1997 : PubMed

            

    Title: Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors
    Abreo MA, Lin NH, Garvey DS, Gunn DE, Hettinger AM, Wasicak JT, Pavlik PA, Martin YC, Donnelly-Roberts D and Holladay MW <4 more author(s)>
    Ref: Journal of Medicinal Chemistry, 39:817, 1996 : PubMed

            

    Title: In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418
    Donnelly-Roberts D, Xue IC, Arneric SP, Sullivan JP
    Ref: Brain Research, 719:36, 1996 : PubMed

            

    Title: Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor
    Gopalakrishnan M, Monteggia LM, Anderson DJ, Molinari EJ, Piattoni-Kaplan M, Donnelly-Roberts D, Arneric SP, Sullivan JP
    Ref: Journal of Pharmacology & Experimental Therapeutics, 276:289, 1996 : PubMed

            

    Title: A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand
    Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Piattoni-Kaplan M, Campbell JE, McKenna DG, Molinari E and Arneric SP <5 more author(s)>
    Ref: Neuropharmacology, 35:725, 1996 : PubMed

            

    Title: Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties
    Arneric SP, Sullivan JP, Decker MW, Brioni JD, Bannon AW, Briggs CA, Donnelly-Roberts D, Radek RJ, Marsh KC and Buccafusco JJ <2 more author(s)>
    Ref: Alzheimer Disease & Associated Disorders, 9 Suppl 2:50, 1995 : PubMed

            

    Title: Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors
    Decker MW, Anderson DJ, Brioni JD, Donnelly-Roberts D, Kang CH, O'Neill AB, Piattoni-Kaplan M, Swanson S, Sullivan JP
    Ref: European Journal of Pharmacology, 280:79, 1995 : PubMed

            

    Title: Functional modulation of human ganglionic-like neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists
    Donnelly-Roberts D, Arneric SP, Sullivan JP
    Ref: Biochemical & Biophysical Research Communications, 213:657, 1995 : PubMed

            

    Title: Stable expression and pharmacological properties of the human alpha 7 nicotinic acetylcholine receptor
    Gopalakrishnan M, Buisson B, Touma E, Giordano T, Campbell JE, Hu IC, Donnelly-Roberts D, Arneric SP, Bertrand D, Sullivan JP
    Ref: European Journal of Pharmacology, 290:237, 1995 : PubMed

            

    Title: Cholinergic channel activators: novel opportunities for the treatment of CNS disorders
    Sullivan JP, Decker MW, Donnelly-Roberts D, Brioni JD, Bannon AW, Holladay MW, Anderson DJ, Briggs CA, Williams M, Arneric SP
    Ref: Proc West Pharmacol Soc, 38:127, 1995 : PubMed

            

    Title: (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization
    Arneric SP, Sullivan JP, Briggs CA, Donnelly-Roberts D, Anderson DJ, Raszkiewicz JL, Hughes ML, Cadman ED, Adams P, Garvey DS
    Ref: Journal of Pharmacology & Experimental Therapeutics, 270:310, 1994 : PubMed

            

    Title: Pathogenesis of hyperacute experimental autoimmune myasthenia gravis. Acetylcholine receptor/cholinergic site/receptor function/autoimmunity
    Mihovilovic M, Donnelly-Roberts D, Richman DP, Martinez-Carrion M
    Ref: J Immunol, 152:5997, 1994 : PubMed

            

    Title: (+/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors
    Sullivan JP, Decker MW, Brioni JD, Donnelly-Roberts D, Anderson DJ, Bannon AW, Kang CH, Adams P, Piattoni-Kaplan M, Buckley MJ
    Ref: Journal of Pharmacology & Experimental Therapeutics, 271:624, 1994 : PubMed

            

    Title: Effects of mutations of Torpedo acetylcholine receptor alpha 1 subunit residues 184-200 on alpha-bungarotoxin binding in a recombinant fusion protein
    Chaturvedi V, Donnelly-Roberts D, Lentz TL
    Ref: Biochemistry, 32:9570, 1993 : PubMed

            

    Title: Sodium dodecyl sulfate- and carbamylcholine-induced changes in circular dichroism spectra of acetylcholine receptor synthetic peptides
    Donnelly-Roberts D, Lentz TL
    Ref: Brain Research Mol Brain Res, 19:55, 1993 : PubMed

            

    Title: Substitution of Torpedo acetylcholine receptor alpha 1-subunit residues with snake alpha 1- and rat nerve alpha 3-subunit residues in recombinant fusion proteins: effect on alpha-bungarotoxin binding
    Chaturvedi V, Donnelly-Roberts D, Lentz TL
    Ref: Biochemistry, 31:1370, 1992 : PubMed

            

    Title: Binding sites for alpha-bungarotoxin and the noncompetitive inhibitor phencyclidine on a synthetic peptide comprising residues 172-227 of the alpha-subunit of the nicotinic acetylcholine receptor
    Donnelly-Roberts D, Lentz TL
    Ref: Biochemistry, 30:7484, 1991 : PubMed

            

    Title: Structural and conformational similarity between synthetic peptides of curaremimetic neurotoxins and rabies virus glycoprotein
    Donnelly-Roberts D, Lentz TL
    Ref: Brain Research Mol Brain Res, 11:107, 1991 : PubMed

            

    Title: Antibodies against an alpha-bungarotoxin-binding peptide of the alpha-subunit of the acetylcholine receptor
    Donnelly-Roberts D, Lentz TL
    Ref: Biochemical & Biophysical Research Communications, 160:289, 1989 : PubMed

            

    Title: Synthetic peptides of neurotoxins and rabies virus glycoprotein behave as antagonists in a functional assay for the acetylcholine receptor
    Donnelly-Roberts D, Lentz TL
    Ref: Pept Res, 2:221, 1989 : PubMed

            

    Title: Synthetic peptides in the study of the interaction of rabies virus and the acetylcholine receptor
    Lentz TL, Hawrot E, Donnelly-Roberts D, Wilson PT
    Ref: Adv Biochem Psychopharmacol, 44:57, 1988 : PubMed

            


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