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| Title : Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter - Ennis_2015_ACS.Chem.Neurosci_6_417 |
| Author(s) : Ennis EA , Wright J , Retzlaff CL , McManus OB , Lin Z , Huang X , Wu M , Li M , Daniels JS , Lindsley CW , Hopkins CR , Blakely RD |
| Ref : ACS Chem Neurosci , 6 :417 , 2015 |
| Abstract : Ennis_2015_ACS.Chem.Neurosci_6_417 |
| ESTHER : Ennis_2015_ACS.Chem.Neurosci_6_417 |
| PubMedSearch : Ennis_2015_ACS.Chem.Neurosci_6_417 |
| PubMedID: 25560927 |
| Title : Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models - Digby_2012_J.Neurosci_32_8532 |
| Author(s) : Digby GJ , Noetzel MJ , Bubser M , Utley TJ , Walker AG , Byun NE , LeBois EP , Xiang Z , Sheffler DJ , Cho HP , Davis AA , Nemirovsky NE , Mennenga SE , Camp BW , Bimonte-Nelson HA , Bode J , Italiano K , Morrison R , Daniels JS , Niswender CM , Olive MF , Lindsley CW , Jones CK , Conn PJ |
| Ref : Journal of Neuroscience , 32 :8532 , 2012 |
| Abstract : Digby_2012_J.Neurosci_32_8532 |
| ESTHER : Digby_2012_J.Neurosci_32_8532 |
| PubMedSearch : Digby_2012_J.Neurosci_32_8532 |
| PubMedID: 22723693 |
| Title : Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012 - Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| Author(s) : Melancon BJ , Lamers AP , Bridges TM , Sulikowski GA , Utley TJ , Sheffler DJ , Noetzel MJ , Morrison RD , Daniels JS , Niswender CM , Jones CK , Conn PJ , Lindsley CW , Wood MR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1044 , 2012 |
| Abstract : Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| ESTHER : Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| PubMedSearch : Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| PubMedID: 22197142 |
| Title : Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor - Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| Author(s) : Salovich JM , Vinson PN , Sheffler DJ , Lamsal A , Utley TJ , Blobaum AL , Bridges TM , Le U , Jones CK , Wood MR , Daniels JS , Conn PJ , Niswender CM , Lindsley CW , Hopkins CR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :5084 , 2012 |
| Abstract : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| ESTHER : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| PubMedSearch : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| PubMedID: 22738637 |
| Title : The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease - Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| Author(s) : Jones CK , Bubser M , Thompson AD , Dickerson JW , Turle-Lorenzo N , Amalric M , Blobaum AL , Bridges TM , Morrison RD , Jadhav S , Engers DW , Italiano K , Bode J , Daniels JS , Lindsley CW , Hopkins CR , Conn PJ , Niswender CM |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 340 :404 , 2012 |
| Abstract : Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| ESTHER : Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| PubMedSearch : Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| PubMedID: 22088953 |
| Title : Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): the development of ML169, an MLPCN probe - Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| Author(s) : Reid PR , Bridges TM , Sheffler DJ , Cho HP , Lewis LM , Days E , Daniels JS , Jones CK , Niswender CM , Weaver CD , Conn PJ , Lindsley CW , Wood MR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2697 , 2011 |
| Abstract : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| ESTHER : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| PubMedSearch : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| PubMedID: 21194936 |