Full name : Cygler Mirek
First name : Mirek
Mail : Biotechnology Research Institute NRCC, 6100 Royalmount Ave, Montreal, Quebec H4P 2R2
Zip Code :
City :
Country : Canada
Email : Miroslaw.cygler@usask.ca
Phone : 514-496-6321
Fax : 514-496-5143
Website :
Directory :
| Title : Defining substrate characteristics from 3D structure\; perspective on EstA structure - Schrag_2004_Structure.(Camb)_12_521 |
| Author(s) : Schrag JD , Cygler M |
| Ref : Structure , 12 :521 , 2004 |
| Abstract : Schrag_2004_Structure.(Camb)_12_521 |
| ESTHER : Schrag_2004_Structure.(Camb)_12_521 |
| PubMedSearch : Schrag_2004_Structure.(Camb)_12_521 |
| PubMedID: 15062074 |
| Gene_locus related to this paper: aspni-EstA |
| Title : Structure and conformational flexibility of Candida rugosa lipase - Cygler_1999_Biochim.Biophys.Acta_1441_205 |
| Author(s) : Cygler M , Schrag JD |
| Ref : Biochimica & Biophysica Acta , 1441 :205 , 1999 |
| Abstract : Cygler_1999_Biochim.Biophys.Acta_1441_205 |
| ESTHER : Cygler_1999_Biochim.Biophys.Acta_1441_205 |
| PubMedSearch : Cygler_1999_Biochim.Biophys.Acta_1441_205 |
| PubMedID: 10570248 |
| Title : Crystal structure of Kex1deltap, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae - Shilton_1997_Biochemistry_36_9002 |
| Author(s) : Shilton BH , Thomas DY , Cygler M |
| Ref : Biochemistry , 36 :9002 , 1997 |
| Abstract : Shilton_1997_Biochemistry_36_9002 |
| ESTHER : Shilton_1997_Biochemistry_36_9002 |
| PubMedSearch : Shilton_1997_Biochemistry_36_9002 |
| PubMedID: 9220988 |
| Title : The open conformation of a Pseudomonas lipase - Schrag_1997_Structure_5_187 |
| Author(s) : Schrag JD , Li Y , Cygler M , Lang D , Burgdorf T , Hecht HJ , Schmid RD , Schomburg D , Rydel TJ , Oliver JD , Strickland LC , Dunaway CM , Larson SB , Day J , McPherson A |
| Ref : Structure , 5 :187 , 1997 |
| Abstract : Schrag_1997_Structure_5_187 |
| ESTHER : Schrag_1997_Structure_5_187 |
| PubMedSearch : Schrag_1997_Structure_5_187 |
| PubMedID: 9032074 |
| Gene_locus related to this paper: burce-lipaa |
| Title : High-level production of recombinant Geotrichum candidum lipases in yeast Pichia pastoris - Holmquist_1997_Protein.Expr.Purif_11_35 |
| Author(s) : Holmquist M , Tessier DC , Cygler M |
| Ref : Protein Expr Purif , 11 :35 , 1997 |
| Abstract : Holmquist_1997_Protein.Expr.Purif_11_35 |
| ESTHER : Holmquist_1997_Protein.Expr.Purif_11_35 |
| PubMedSearch : Holmquist_1997_Protein.Expr.Purif_11_35 |
| PubMedID: 9325136 |
| Title : Lipases and alpha\/beta hydrolase fold - Schrag_1997_Methods.Enzymol_284_85 |
| Author(s) : Schrag JD , Cygler M |
| Ref : Methods Enzymol , 284 :85 , 1997 |
| Abstract : Schrag_1997_Methods.Enzymol_284_85 |
| ESTHER : Schrag_1997_Methods.Enzymol_284_85 |
| PubMedSearch : Schrag_1997_Methods.Enzymol_284_85 |
| PubMedID: 9379946 |
| Title : Purification and characterization of a Penicillium sp. lipase which discriminates against diglycerides - Gulomova_1996_Lipids_31_379 |
| Author(s) : Gulomova K , Ziomek E , Schrag JD , Davranov K , Cygler M |
| Ref : Lipids , 31 :379 , 1996 |
| Abstract : Gulomova_1996_Lipids_31_379 |
| ESTHER : Gulomova_1996_Lipids_31_379 |
| PubMedSearch : Gulomova_1996_Lipids_31_379 |
| PubMedID: 8743049 |
| Title : Crystallization of a soluble form of the Kex1p serine carboxypeptidase from Saccharomyces cerevisiae - Shilton_1996_Protein.Sci_5_395 |
| Author(s) : Shilton BH , Li Y , Tessier D , Thomas DY , Cygler M |
| Ref : Protein Science , 5 :395 , 1996 |
| Abstract : Shilton_1996_Protein.Sci_5_395 |
| ESTHER : Shilton_1996_Protein.Sci_5_395 |
| PubMedSearch : Shilton_1996_Protein.Sci_5_395 |
| PubMedID: 8745419 |
| Gene_locus related to this paper: yeast-kex01 |
| Title : Structural determinants defining common stereoselectivity of lipases toward secondary alcohols - Cygler_1995_Can.J.Microbiol_41 Suppl 1_289 |
| Author(s) : Cygler M , Grochulski P , Schrag JD |
| Ref : Can J Microbiol , 41 Suppl 1 :289 , 1995 |
| Abstract : Cygler_1995_Can.J.Microbiol_41 Suppl 1_289 |
| ESTHER : Cygler_1995_Can.J.Microbiol_41 Suppl 1_289 |
| PubMedSearch : Cygler_1995_Can.J.Microbiol_41 Suppl 1_289 |
| PubMedID: 7606666 |
| Title : Redesigning the active site of Geotrichum candidum lipase - Schrag_1995_Protein.Eng_8_835 |
| Author(s) : Schrag JD , Vernet T , Laramee L , Thomas DY , Recktenwald A , Okoniewska M , Ziomek E , Cygler M |
| Ref : Protein Engineering , 8 :835 , 1995 |
| Abstract : Schrag_1995_Protein.Eng_8_835 |
| ESTHER : Schrag_1995_Protein.Eng_8_835 |
| PubMedSearch : Schrag_1995_Protein.Eng_8_835 |
| PubMedID: 8637854 |
| Title : Substrate Binding Site and the Role of the FLAP Loop in Candida rugosa Lipase, A Close Relative of Acetylcholinesterase - |
| Author(s) : Cygler M , Grochulski P , Schrag JD |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :71 , 1995 |
| PubMedID: |
| Title : Expression and characterization of Geotrichum candidum lipase I gene. Comparison of specificity profile with lipase II - Bertolini_1995_Eur.J.Biochem_228_863 |
| Author(s) : Bertolini MC , Schrag JD , Cygler M , Ziomek E , Thomas DY , Vernet T |
| Ref : European Journal of Biochemistry , 228 :863 , 1995 |
| Abstract : Bertolini_1995_Eur.J.Biochem_228_863 |
| ESTHER : Bertolini_1995_Eur.J.Biochem_228_863 |
| PubMedSearch : Bertolini_1995_Eur.J.Biochem_228_863 |
| PubMedID: 7737187 |
| Gene_locus related to this paper: geoca-1lipa , geoca-2lipa |
| Title : Two conformational states of Candida rugosa lipase - Grochulski_1994_Protein.Sci_3_82 |
| Author(s) : Grochulski P , Li Y , Schrag JD , Cygler M |
| Ref : Protein Science , 3 :82 , 1994 |
| Abstract : Grochulski_1994_Protein.Sci_3_82 |
| ESTHER : Grochulski_1994_Protein.Sci_3_82 |
| PubMedSearch : Grochulski_1994_Protein.Sci_3_82 |
| PubMedID: 8142901 |
| Gene_locus related to this paper: canru-1lipa |
| Title : Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase - Grochulski_1994_Biochemistry_33_3494 |
| Author(s) : Grochulski P , Bouthillier F , Kazlauskas RJ , Serreqi AN , Schrag JD , Ziomek E , Cygler M |
| Ref : Biochemistry , 33 :3494 , 1994 |
| Abstract : Grochulski_1994_Biochemistry_33_3494 |
| ESTHER : Grochulski_1994_Biochemistry_33_3494 |
| PubMedSearch : Grochulski_1994_Biochemistry_33_3494 |
| PubMedID: 8142346 |
| Gene_locus related to this paper: canru-1lipa |
| Title : A structural basis for the chiral preferences of lipases - |
| Author(s) : Cygler M , Grochulski P , Kazlauskas RJ , Schrag JD , Bouthillier F , Rubin B , Serreqi AN , Gupta AK |
| Ref : Journal of the American Chemical Society , 116 :3180 , 1994 |
| PubMedID: |
| Gene_locus related to this paper: canru-1lipa |
| Title : Polymorphism in the lipase genes of Geotrichum candidum strains - Bertolini_1994_Eur.J.Biochem_219_119 |
| Author(s) : Bertolini MC , Laramee L , Thomas DY , Cygler M , Schrag JD , Vernet T |
| Ref : European Journal of Biochemistry , 219 :119 , 1994 |
| Abstract : Bertolini_1994_Eur.J.Biochem_219_119 |
| ESTHER : Bertolini_1994_Eur.J.Biochem_219_119 |
| PubMedSearch : Bertolini_1994_Eur.J.Biochem_219_119 |
| PubMedID: 8306978 |
| Gene_locus related to this paper: geoca-1lipa , geoca-2lipa |
| Title : Insights into interfacial activation from an open structure of Candida rugosa lipase - Grochulski_1993_J.Biol.Chem_268_12843 |
| Author(s) : Grochulski P , Li Y , Schrag JD , Bouthillier F , Smith P , Harrison D , Rubin B , Cygler M |
| Ref : Journal of Biological Chemistry , 268 :12843 , 1993 |
| Abstract : Grochulski_1993_J.Biol.Chem_268_12843 |
| ESTHER : Grochulski_1993_J.Biol.Chem_268_12843 |
| PubMedSearch : Grochulski_1993_J.Biol.Chem_268_12843 |
| PubMedID: 8509417 |
| Gene_locus related to this paper: canru-1lipa , geoca-1lipa |
| Title : Cloning and expression of Geotrichum candidum lipase II gene in yeast. Probing of the enzyme active site by site-directed mutagenesis - Vernet_1993_J.Biol.Chem_268_26212 |
| Author(s) : Vernet T , Ziomek E , Recktenwald A , Schrag JD , de Montigny C , Tessier DC , Thomas DY , Cygler M |
| Ref : Journal of Biological Chemistry , 268 :26212 , 1993 |
| Abstract : Vernet_1993_J.Biol.Chem_268_26212 |
| ESTHER : Vernet_1993_J.Biol.Chem_268_26212 |
| PubMedSearch : Vernet_1993_J.Biol.Chem_268_26212 |
| PubMedID: 7902836 |
| Title : Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins - Cygler_1993_Protein.Sci_2_366 |
| Author(s) : Cygler M , Schrag JD , Sussman JL , Harel M , Silman I , Gentry MK , Doctor BP |
| Ref : Protein Science , 2 :366 , 1993 |
| Abstract : Cygler_1993_Protein.Sci_2_366 |
| ESTHER : Cygler_1993_Protein.Sci_2_366 |
| PubMedSearch : Cygler_1993_Protein.Sci_2_366 |
| PubMedID: 8453375 |
| Title : 1.8 A refined structure of the lipase from Geotrichum candidum - Schrag_1993_J.Mol.Biol_230_575 |
| Author(s) : Schrag JD , Cygler M |
| Ref : Journal of Molecular Biology , 230 :575 , 1993 |
| Abstract : Schrag_1993_J.Mol.Biol_230_575 |
| ESTHER : Schrag_1993_J.Mol.Biol_230_575 |
| PubMedSearch : Schrag_1993_J.Mol.Biol_230_575 |
| PubMedID: 8464065 |
| Gene_locus related to this paper: geoca-1lipa , geoca-2lipa |
| Title : The alpha\/beta hydrolase fold - Ollis_1992_Prot.Engin_5_197 |
| Author(s) : Ollis DL , Cheah E , Cygler M , Dijkstra B , Frolow F , Franken SM , Harel M , Remington SJ , Silman I , Schrag JD , Sussman JL , Verschueren KHG , Goldman A |
| Ref : Protein Engineering , 5 :197 , 1992 |
| Abstract : Ollis_1992_Prot.Engin_5_197 |
| ESTHER : Ollis_1992_Prot.Engin_5_197 |
| PubMedSearch : Ollis_1992_Prot.Engin_5_197 |
| PubMedID: 1409539 |
| Title : Sequence Alignment of Esterases and Lipases Based on 3-D Structures of Two Members of This Family - |
| Author(s) : Cygler M , Schrag JD |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :109 , 1992 |
| PubMedID: |
| Title : Pancreatic lipases: evolutionary intermediates in a positional change of catalytic carboxylates? - Schrag_1992_J.Biol.Chem_267_4300 |
| Author(s) : Schrag JD , Winkler FK , Cygler M |
| Ref : Journal of Biological Chemistry , 267 :4300 , 1992 |
| Abstract : Schrag_1992_J.Biol.Chem_267_4300 |
| ESTHER : Schrag_1992_J.Biol.Chem_267_4300 |
| PubMedSearch : Schrag_1992_J.Biol.Chem_267_4300 |
| PubMedID: 1537823 |
| Gene_locus related to this paper: geoca-1lipa |
| Title : Ser-His-Glu triad forms the catalytic site of the lipase from Geotrichum candidum - Schrag_1991_Nature_351_761 |
| Author(s) : Schrag JD , Li YG , Wu S , Cygler M |
| Ref : Nature , 351 :761 , 1991 |
| Abstract : Schrag_1991_Nature_351_761 |
| ESTHER : Schrag_1991_Nature_351_761 |
| PubMedSearch : Schrag_1991_Nature_351_761 |
| PubMedID: 2062369 |
| Gene_locus related to this paper: geoca-1lipa |