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| Title : Pharmacological blockade of 2-AG degradation ameliorates clinical, neuroinflammatory and synaptic alterations in experimental autoimmune encephalomyelitis - Guadalupi_2024_Neuropharmacol__109940 |
| Author(s) : Guadalupi L , Mandolesi G , Vanni V , Balletta S , Caioli S , Pavlovic A , De Vito F , Fresegna D , Sanna K , Vitiello L , Nencini M , Tartacca A , Mariani F , Rovella V , Schippling S , Ruf I , Collin L , Centonze D , Musella A |
| Ref : Neuropharmacology , :109940 , 2024 |
| Abstract : Guadalupi_2024_Neuropharmacol__109940 |
| ESTHER : Guadalupi_2024_Neuropharmacol__109940 |
| PubMedSearch : Guadalupi_2024_Neuropharmacol__109940 |
| PubMedID: 38570068 |
| Title : Preclinical Evaluation of the Reversible Monoacylglycerol Lipase PET Tracer (R)-[(11) C]YH132: Application in Drug Development and Neurodegenerative Diseases - He_2024_Chembiochem__e202300819 |
| Author(s) : He Y , Delparente A , Jie C , Keller C , Humm R , Heer D , Collin L , Schibli R , Gobbi L , Grether U , Mu L |
| Ref : Chembiochem , :e202300819 , 2024 |
| Abstract : He_2024_Chembiochem__e202300819 |
| ESTHER : He_2024_Chembiochem__e202300819 |
| PubMedSearch : He_2024_Chembiochem__e202300819 |
| PubMedID: 38441502 |
| Title : Identification of (R)-[(18)F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development - He_2023_J.Nucl.Med__ |
| Author(s) : He Y , Kramer SD , Grether U , Wittwer MB , Collin L , Kuhn B , Topp A , Heer D , O'Hara F , Honer M , Pavlovic A , Richter H , Ritter M , Rombach D , Keller C , Gobbi L , Mu L |
| Ref : J Nucl Med , : , 2023 |
| Abstract : He_2023_J.Nucl.Med__ |
| ESTHER : He_2023_J.Nucl.Med__ |
| PubMedSearch : He_2023_J.Nucl.Med__ |
| PubMedID: 38164615 |
| Title : A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence - Jiang_2023_Nat.Commun_14_8039 |
| Author(s) : Jiang M , Huizenga MCW , Wirt JL , Paloczi J , Amedi A , van den Berg R , Benz J , Collin L , Deng H , Di X , Driever WF , Florea BI , Grether U , Janssen APA , Hankemeier T , Heitman LH , Lam TW , Mohr F , Pavlovic A , Ruf I , van den Hurk H , Stevens AF , van der Vliet D , van der Wel T , Wittwer MB , van Boeckel CAA , Pacher P , Hohmann AG , van der Stelt M |
| Ref : Nat Commun , 14 :8039 , 2023 |
| Abstract : Jiang_2023_Nat.Commun_14_8039 |
| ESTHER : Jiang_2023_Nat.Commun_14_8039 |
| PubMedSearch : Jiang_2023_Nat.Commun_14_8039 |
| PubMedID: 38052772 |
| Title : Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging - He_2022_J.Med.Chem_65_2191 |
| Author(s) : He Y , Schild M , Grether U , Benz J , Leibrock L , Heer D , Topp A , Collin L , Kuhn B , Wittwer M , Keller C , Gobbi LC , Schibli R , Mu L |
| Ref : Journal of Medicinal Chemistry , 65 :2191 , 2022 |
| Abstract : He_2022_J.Med.Chem_65_2191 |
| ESTHER : He_2022_J.Med.Chem_65_2191 |
| PubMedSearch : He_2022_J.Med.Chem_65_2191 |
| PubMedID: 35089028 |
| Gene_locus related to this paper: human-MGLL |
| Title : A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature - Kemble_2022_PLoS.One_17_e0268590 |
| Author(s) : Kemble AM , Hornsperger B , Ruf I , Richter H , Benz J , Kuhn B , Heer D , Wittwer M , Engelhardt B , Grether U , Collin L |
| Ref : PLoS ONE , 17 :e0268590 , 2022 |
| Abstract : Kemble_2022_PLoS.One_17_e0268590 |
| ESTHER : Kemble_2022_PLoS.One_17_e0268590 |
| PubMedSearch : Kemble_2022_PLoS.One_17_e0268590 |
| PubMedID: 36084029 |
| Gene_locus related to this paper: human-MGLL |
| Title : Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain - He_2022_Eur.J.Med.Chem_243_114750 |
| Author(s) : He Y , Grether U , Taddio MF , Meier C , Keller C , Edelmann MR , Honer M , Huber S , Wittwer MB , Heer D , Richter H , Collin L , Hug MN , Hilbert M , Postmus AGJ , Stevens AF , van der Stelt M , Kramer SD , Schibli R , Mu L , Gobbi LC |
| Ref : Eur Journal of Medicinal Chemistry , 243 :114750 , 2022 |
| Abstract : He_2022_Eur.J.Med.Chem_243_114750 |
| ESTHER : He_2022_Eur.J.Med.Chem_243_114750 |
| PubMedSearch : He_2022_Eur.J.Med.Chem_243_114750 |
| PubMedID: 36137365 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold - He_2022_Nucl.Med.Biol_108-109_24 |
| Author(s) : He Y , Gobbi LC , Herde AM , Rombach D , Ritter M , Kuhn B , Wittwer MB , Heer D , Hornsperger B , Bell C , O'Hara F , Benz J , Honer M , Keller C , Collin L , Richter H , Schibli R , Grether U , Mu L |
| Ref : Nucl Med Biol , 108-109 :24 , 2022 |
| Abstract : He_2022_Nucl.Med.Biol_108-109_24 |
| ESTHER : He_2022_Nucl.Med.Biol_108-109_24 |
| PubMedSearch : He_2022_Nucl.Med.Biol_108-109_24 |
| PubMedID: 35248850 |