Report for Cheung J

Title : Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6 - McGuire_2021_Chem.Res.Toxicol_34_804

Author(s) : McGuire JR , Bester SM , Guelta MA , Cheung J , Langley C , Winemiller MD , Bae SY , Funk V , Myslinski JM , Pegan SD , Height JJ

Ref : Chemical Research in Toxicology , 34 :804 , 2021

Abstract : McGuire_2021_Chem.Res.Toxicol_34_804

ESTHER : McGuire_2021_Chem.Res.Toxicol_34_804

PubMedSearch : McGuire_2021_Chem.Res.Toxicol_34_804

PubMedID: 33538594

Gene_locus related to this paper: human-ACHE

Title : beta2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure - Vanhaesebrouck_2019_Brain_142_3713

Author(s) : Vanhaesebrouck AE , Webster R , Maxwell S , Rodriguez Cruz PM , Cossins J , Wickens J , Liu WW , Cetin H , Cheung J , Ramjattan H , Palace J , Beeson D

Ref : Brain , 142 :3713 , 2019

Abstract : Vanhaesebrouck_2019_Brain_142_3713

ESTHER : Vanhaesebrouck_2019_Brain_142_3713

PubMedSearch : Vanhaesebrouck_2019_Brain_142_3713

PubMedID: 31633155

Title : Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups - Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

Author(s) : Rosenberry TL , Cheung J

Ref : Chemico-Biological Interactions , : , 2019

Abstract : Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

ESTHER : Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

PubMedSearch : Rosenberry_2019_Chem.Biol.Interact_13ChEPon_

PubMedID: 31175846

Title : The structural and biochemical impacts of monomerizing human acetylcholinesterase - Bester_2019_Protein.Sci_28_1106

Author(s) : Bester SM , Adipietro KA , Funk VL , Myslinski JM , Keul ND , Cheung J , Wilder PT , Wood ZA , Weber DJ , Height JJ , Pegan SD

Ref : Protein Science , 28 :1106 , 2019

Abstract : Bester_2019_Protein.Sci_28_1106

ESTHER : Bester_2019_Protein.Sci_28_1106

PubMedSearch : Bester_2019_Protein.Sci_28_1106

PubMedID: 30993792

Gene_locus related to this paper: human-ACHE

Title : A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants - Pilkington_2018_BMC.Genomics_19_257

Author(s) : Pilkington SM , Crowhurst R , Hilario E , Nardozza S , Fraser L , Peng Y , Gunaseelan K , Simpson R , Tahir J , Deroles SC , Templeton K , Luo Z , Davy M , Cheng C , McNeilage M , Scaglione D , Liu Y , Zhang Q , Datson P , De Silva N , Gardiner SE , Bassett H , Chagne D , McCallum J , Dzierzon H , Deng C , Wang YY , Barron L , Manako K , Bowen J , Foster TM , Erridge ZA , Tiffin H , Waite CN , Davies KM , Grierson EP , Laing WA , Kirk R , Chen X , Wood M , Montefiori M , Brummell DA , Schwinn KE , Catanach A , Fullerton C , Li D , Meiyalaghan S , Nieuwenhuizen N , Read N , Prakash R , Hunter D , Zhang H , McKenzie M , Knabel M , Harris A , Allan AC , Gleave A , Chen A , Janssen BJ , Plunkett B , Ampomah-Dwamena C , Voogd C , Leif D , Lafferty D , Souleyre EJF , Varkonyi-Gasic E , Gambi F , Hanley J , Yao JL , Cheung J , David KM , Warren B , Marsh K , Snowden KC , Lin-Wang K , Brian L , Martinez-Sanchez M , Wang M , Ileperuma N , Macnee N , Campin R , McAtee P , Drummond RSM , Espley RV , Ireland HS , Wu R , Atkinson RG , Karunairetnam S , Bulley S , Chunkath S , Hanley Z , Storey R , Thrimawithana AH , Thomson S , David C , Testolin R , Huang H , Hellens RP , Schaffer RJ

Ref : BMC Genomics , 19 :257 , 2018

Abstract : Pilkington_2018_BMC.Genomics_19_257

ESTHER : Pilkington_2018_BMC.Genomics_19_257

PubMedSearch : Pilkington_2018_BMC.Genomics_19_257

PubMedID: 29661190

Gene_locus related to this paper: actde-CXE3 , actde-CXE5 , actch-a0a2r6p9v4 , actch-a0a2r6phk8 , actch-a0a2r6pty2 , actch-q0zpu6 , actcc-a0a2r6q553 , actcc-a0a2r6quq2 , actcc-a0a2r6q2m9 , actcc-a0a2r6q2n7 , actcc-a0a2r6ru97 , actcc-a0a2r6r3e8 , actcc-a0a2r6qy24 , actcc-a0a2r6pzy5 , actcc-a0a2r6p5n3 , actcc-a0a2r6qdp0 , actcc-a0a2r6qgs9

Title : Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6 - Bester_2018_Chem.Res.Toxicol_31_1405

Author(s) : Bester SM , Guelta MA , Cheung J , Winemiller MD , Bae SY , Myslinski J , Pegan SD , Height JJ

Ref : Chemical Research in Toxicology , 31 :1405 , 2018

Abstract : Bester_2018_Chem.Res.Toxicol_31_1405

ESTHER : Bester_2018_Chem.Res.Toxicol_31_1405

PubMedSearch : Bester_2018_Chem.Res.Toxicol_31_1405

PubMedID: 30462502

Gene_locus related to this paper: human-ACHE

Title : Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance - Cheung_2018_Structure_26_130

Author(s) : Cheung J , Mahmood A , Kalathur R , Liu L , Carlier PR

Ref : Structure , 26 :130 , 2018

Abstract : Cheung_2018_Structure_26_130

ESTHER : Cheung_2018_Structure_26_130

PubMedSearch : Cheung_2018_Structure_26_130

PubMedID: 29276037

Gene_locus related to this paper: anoga-ACHE1

Title : Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface - Franklin_2016_Proteins_84_1246

Author(s) : Franklin MC , Rudolph MJ , Ginter C , Cassidy MS , Cheung J

Ref : Proteins , 84 :1246 , 2016

Abstract : Franklin_2016_Proteins_84_1246

ESTHER : Franklin_2016_Proteins_84_1246

PubMedSearch : Franklin_2016_Proteins_84_1246

PubMedID: 27191504

Gene_locus related to this paper: human-ACHE

Title : Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence - Rosenberry_2016_Chem.Biol.Interact_259_78

Author(s) : Rosenberry TL , Martin PK , Nix AJ , Wildman SA , Cheung J , Snyder SA , Tan RX

Ref : Chemico-Biological Interactions , 259 :78 , 2016

Abstract : Rosenberry_2016_Chem.Biol.Interact_259_78

ESTHER : Rosenberry_2016_Chem.Biol.Interact_259_78

PubMedSearch : Rosenberry_2016_Chem.Biol.Interact_259_78

PubMedID: 27297626

Title : Structural genomics for drug design against the pathogen Coxiella burnetii - Franklin_2015_Proteins_83_2124

Author(s) : Franklin MC , Cheung J , Rudolph MJ , Burshteyn F , Cassidy M , Gary E , Hillerich B , Yao ZK , Carlier PR , Totrov M , Love JD

Ref : Proteins , 83 :2124 , 2015

Abstract : Franklin_2015_Proteins_83_2124

ESTHER : Franklin_2015_Proteins_83_2124

PubMedSearch : Franklin_2015_Proteins_83_2124

PubMedID: 26033498

Gene_locus related to this paper: coxbu-CBU1769

Title : Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination - Cheung_2014_J.Mol.Neurosci_53_506

Author(s) : Cheung J , Beri V , Shiomi K , Rosenberry TL

Ref : Journal of Molecular Neuroscience , 53 :506 , 2014

Abstract : Cheung_2014_J.Mol.Neurosci_53_506

ESTHER : Cheung_2014_J.Mol.Neurosci_53_506

PubMedSearch : Cheung_2014_J.Mol.Neurosci_53_506

PubMedID: 24573600

Title : Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility - Cheung_2013_ACS.Med.Chem.Lett_4_1091

Author(s) : Cheung J , Gary EN , Shiomi K , Rosenberry TL

Ref : ACS Med Chem Lett , 4 :1091 , 2013

Abstract : Cheung_2013_ACS.Med.Chem.Lett_4_1091

ESTHER : Cheung_2013_ACS.Med.Chem.Lett_4_1091

PubMedSearch : Cheung_2013_ACS.Med.Chem.Lett_4_1091

PubMedID: 24900610

Gene_locus related to this paper: human-ACHE

Title : The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity - Beri_2013_Biochemistry_52_7486

Author(s) : Beri V , Wildman SA , Shiomi K , Al-Rashid ZF , Cheung J , Rosenberry TL

Ref : Biochemistry , 52 :7486 , 2013

Abstract : Beri_2013_Biochemistry_52_7486

ESTHER : Beri_2013_Biochemistry_52_7486

PubMedSearch : Beri_2013_Biochemistry_52_7486

PubMedID: 24040835

Title : Structures of human acetylcholinesterase in complex with pharmacologically important ligands - Cheung_2012_J.Med.Chem_55_10282

Author(s) : Cheung J , Rudolph MJ , Burshteyn F , Cassidy MS , Gary EN , Love J , Franklin MC , Height JJ

Ref : Journal of Medicinal Chemistry , 55 :10282 , 2012

Abstract : Cheung_2012_J.Med.Chem_55_10282

ESTHER : Cheung_2012_J.Med.Chem_55_10282

PubMedSearch : Cheung_2012_J.Med.Chem_55_10282

PubMedID: 23035744

Gene_locus related to this paper: human-ACHE

Title : Crystal structure of a functional dimer of the PhoQ sensor domain - Cheung_2008_J.Biol.Chem_283_13762

Author(s) : Cheung J , Bingman CA , Reyngold M , Hendrickson WA , Waldburger CD

Ref : Journal of Biological Chemistry , 283 :13762 , 2008

Abstract : Cheung_2008_J.Biol.Chem_283_13762

ESTHER : Cheung_2008_J.Biol.Chem_283_13762

PubMedSearch : Cheung_2008_J.Biol.Chem_283_13762

PubMedID: 18348979

Title : Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans - Wen_2003_Hum.Mol.Genet_12_1131

Author(s) : Wen XY , Hegele RA , Wang J , Wang DY , Cheung J , Wilson M , Yahyapour M , Bai Y , Zhuang L , Skaug J , Young TK , Connelly PW , Koop BF , Tsui LC , Stewart AK

Ref : Hum Mol Genet , 12 :1131 , 2003

Abstract : Wen_2003_Hum.Mol.Genet_12_1131

ESTHER : Wen_2003_Hum.Mol.Genet_12_1131

PubMedSearch : Wen_2003_Hum.Mol.Genet_12_1131

PubMedID: 12719377

Gene_locus related to this paper: human-LIPI

Report for Cheung J

General

References (16)

Report for Cheung J

General

References (16)

1. Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6

2. beta2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure

3. Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups

4. The structural and biochemical impacts of monomerizing human acetylcholinesterase

5. A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants

6. Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6

7. Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance

8. Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface

9. Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence

10. Structural genomics for drug design against the pathogen Coxiella burnetii

11. Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination

12. Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility

13. The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity

14. Structures of human acetylcholinesterase in complex with pharmacologically important ligands

15. Crystal structure of a functional dimer of the PhoQ sensor domain

16. Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans