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Author Report for: Carotti A

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    Title: Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease
    Tonelli M, Catto M, Sabate R, Francesconi V, Laurini E, Pricl S, Pisani L, Miniero DV, Liuzzi GM and Carotti A <5 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 250:115169, 2023 : PubMed

            

    Title: Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds
    Stefanachi A, Leonetti F, Pisani L, Catto M, Carotti A
    Ref: Molecules, 23:, 2018 : PubMed

            

    Title: 3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes
    Park B, Nam JH, Kim JH, Kim HJ, Onnis V, Balboni G, Lee KT, Park JH, Catto M and Lee JY <1 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 27:1179, 2017 : PubMed

            

    Title: Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif
    Pisani L, Farina R, Soto-Otero R, Denora N, Mangiatordi GF, Nicolotti O, Mendez-Alvarez E, Altomare CD, Catto M, Carotti A
    Ref: Molecules, 21:, 2016 : PubMed

            

    Title: Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents
    Pisani L, Farina R, Catto M, Iacobazzi RM, Nicolotti O, Cellamare S, Mangiatordi GF, Denora N, Soto-Otero R and Carotti A <2 more author(s)>
    Ref: Journal of Medicinal Chemistry, 59:6791, 2016 : PubMed

            

    Title: Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases
    Farina R, Pisani L, Catto M, Nicolotti O, Gadaleta D, Denora N, Soto-Otero R, Mendez-Alvarez E, Passos CS and Carotti A <4 more author(s)>
    Ref: Journal of Medicinal Chemistry, 58:5561, 2015 : PubMed

            

    Title: Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors
    Pau A, Catto M, Pinna G, Frau S, Murineddu G, Asproni B, Curzu MM, Pisani L, Leonetti F and Carotti A <3 more author(s)>
    Ref: ChemMedChem, 10:1054, 2015 : PubMed

            

    Title: Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and beta-Amyloid (Abeta) Aggregation
    Tonelli M, Catto M, Tasso B, Novelli F, Canu C, Iusco G, Pisani L, Stradis AD, Denora N and Sparatore F <3 more author(s)>
    Ref: ChemMedChem, 10:1040, 2015 : PubMed

            

    Title: Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase
    Catto M, Pisani L, Leonetti F, Nicolotti O, Pesce P, Stefanachi A, Cellamare S, Carotti A
    Ref: Bioorganic & Medicinal Chemistry, 21:146, 2013 : PubMed

            

    Title: Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase
    Catto M, Berezin AA, Lo Re D, Loizou G, Demetriades M, De Stradis A, Campagna F, Koutentis PA, Carotti A
    Ref: Eur Journal of Medicinal Chemistry, 58C:84, 2012 : PubMed

            

    Title: Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity
    Conejo-Garcia A, Pisani L, Nunez Mdel C, Catto M, Nicolotti O, Leonetti F, Campos JM, Gallo MA, Espinosa A, Carotti A
    Ref: Journal of Medicinal Chemistry, 54:2627, 2011 : PubMed

            

    Title: Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases
    Pisani L, Catto M, Leonetti F, Nicolotti O, Stefanachi A, Campagna F, Carotti A
    Ref: Curr Med Chem, 18:4568, 2011 : PubMed

            

    Title: Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease
    Tasso B, Catto M, Nicolotti O, Novelli F, Tonelli M, Giangreco I, Pisani L, Sparatore A, Boido V and Sparatore F <1 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 46:2170, 2011 : PubMed

            

    Title: Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors
    Pisani L, Catto M, Giangreco I, Leonetti F, Nicolotti O, Stefanachi A, Cellamare S, Carotti A
    Ref: ChemMedChem, 5:1616, 2010 : PubMed

            

    Title: Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors
    Leonetti F, Catto M, Nicolotti O, Pisani L, Cappa A, Stefanachi A, Carotti A
    Ref: Bioorganic & Medicinal Chemistry, 16:7450, 2008 : PubMed

            

    Title: Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors
    Carotti A, de Candia M, Catto M, Borisova TN, Varlamov AV, Mendez-Alvarez E, Soto-Otero R, Voskressensky LG, Altomare CD
    Ref: Bioorganic & Medicinal Chemistry, 14:7205, 2006 : PubMed

            

    Title: Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase
    Bruhlmann C, Ooms F, Carrupt PA, Testa B, Catto M, Leonetti F, Altomare CD, Carotti A
    Ref: Journal of Medicinal Chemistry, 44:3195, 2001 : PubMed

            


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