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| Title : Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease - Tonelli_2023_Eur.J.Med.Chem_250_115169 |
| Author(s) : Tonelli M , Catto M , Sabate R , Francesconi V , Laurini E , Pricl S , Pisani L , Miniero DV , Liuzzi GM , Gatta E , Relini A , Gavin R , Del Rio JA , Sparatore F , Carotti A |
| Ref : Eur Journal of Medicinal Chemistry , 250 :115169 , 2023 |
| Abstract : Tonelli_2023_Eur.J.Med.Chem_250_115169 |
| ESTHER : Tonelli_2023_Eur.J.Med.Chem_250_115169 |
| PubMedSearch : Tonelli_2023_Eur.J.Med.Chem_250_115169 |
| PubMedID: 36753881 |
| Title : Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds - Stefanachi_2018_Molecules_23_ |
| Author(s) : Stefanachi A , Leonetti F , Pisani L , Catto M , Carotti A |
| Ref : Molecules , 23 : , 2018 |
| Abstract : Stefanachi_2018_Molecules_23_ |
| ESTHER : Stefanachi_2018_Molecules_23_ |
| PubMedSearch : Stefanachi_2018_Molecules_23_ |
| PubMedID: 29382051 |
| Title : 3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes - Park_2017_Bioorg.Med.Chem.Lett_27_1179 |
| Author(s) : Park B , Nam JH , Kim JH , Kim HJ , Onnis V , Balboni G , Lee KT , Park JH , Catto M , Carotti A , Lee JY |
| Ref : Bioorganic & Medicinal Chemistry Lett , 27 :1179 , 2017 |
| Abstract : Park_2017_Bioorg.Med.Chem.Lett_27_1179 |
| ESTHER : Park_2017_Bioorg.Med.Chem.Lett_27_1179 |
| PubMedSearch : Park_2017_Bioorg.Med.Chem.Lett_27_1179 |
| PubMedID: 28189420 |
| Title : Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents - Pisani_2016_J.Med.Chem_59_6791 |
| Author(s) : Pisani L , Farina R , Catto M , Iacobazzi RM , Nicolotti O , Cellamare S , Mangiatordi GF , Denora N , Soto-Otero R , Siragusa L , Altomare CD , Carotti A |
| Ref : Journal of Medicinal Chemistry , 59 :6791 , 2016 |
| Abstract : Pisani_2016_J.Med.Chem_59_6791 |
| ESTHER : Pisani_2016_J.Med.Chem_59_6791 |
| PubMedSearch : Pisani_2016_J.Med.Chem_59_6791 |
| PubMedID: 27347731 |
| Title : Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif - Pisani_2016_Molecules_21_ |
| Author(s) : Pisani L , Farina R , Soto-Otero R , Denora N , Mangiatordi GF , Nicolotti O , Mendez-Alvarez E , Altomare CD , Catto M , Carotti A |
| Ref : Molecules , 21 : , 2016 |
| Abstract : Pisani_2016_Molecules_21_ |
| ESTHER : Pisani_2016_Molecules_21_ |
| PubMedSearch : Pisani_2016_Molecules_21_ |
| PubMedID: 26999091 |
| Title : Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases - Farina_2015_J.Med.Chem_58_5561 |
| Author(s) : Farina R , Pisani L , Catto M , Nicolotti O , Gadaleta D , Denora N , Soto-Otero R , Mendez-Alvarez E , Passos CS , Muncipinto G , Altomare CD , Nurisso A , Carrupt PA , Carotti A |
| Ref : Journal of Medicinal Chemistry , 58 :5561 , 2015 |
| Abstract : Farina_2015_J.Med.Chem_58_5561 |
| ESTHER : Farina_2015_J.Med.Chem_58_5561 |
| PubMedSearch : Farina_2015_J.Med.Chem_58_5561 |
| PubMedID: 26107513 |
| Title : Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors - Pau_2015_ChemMedChem_10_1054 |
| Author(s) : Pau A , Catto M , Pinna G , Frau S , Murineddu G , Asproni B , Curzu MM , Pisani L , Leonetti F , Loza MI , Brea J , Pinna GA , Carotti A |
| Ref : ChemMedChem , 10 :1054 , 2015 |
| Abstract : Pau_2015_ChemMedChem_10_1054 |
| ESTHER : Pau_2015_ChemMedChem_10_1054 |
| PubMedSearch : Pau_2015_ChemMedChem_10_1054 |
| PubMedID: 25924828 |
| Title : Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and beta-Amyloid (Abeta) Aggregation - Tonelli_2015_ChemMedChem_10_1040 |
| Author(s) : Tonelli M , Catto M , Tasso B , Novelli F , Canu C , Iusco G , Pisani L , Stradis AD , Denora N , Sparatore A , Boido V , Carotti A , Sparatore F |
| Ref : ChemMedChem , 10 :1040 , 2015 |
| Abstract : Tonelli_2015_ChemMedChem_10_1040 |
| ESTHER : Tonelli_2015_ChemMedChem_10_1040 |
| PubMedSearch : Tonelli_2015_ChemMedChem_10_1040 |
| PubMedID: 25924599 |
| Title : Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase - Catto_2013_Bioorg.Med.Chem_21_146 |
| Author(s) : Catto M , Pisani L , Leonetti F , Nicolotti O , Pesce P , Stefanachi A , Cellamare S , Carotti A |
| Ref : Bioorganic & Medicinal Chemistry , 21 :146 , 2013 |
| Abstract : Catto_2013_Bioorg.Med.Chem_21_146 |
| ESTHER : Catto_2013_Bioorg.Med.Chem_21_146 |
| PubMedSearch : Catto_2013_Bioorg.Med.Chem_21_146 |
| PubMedID: 23199476 |
| Title : Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl\/butyryl cholinesterase - Catto_2012_Eur.J.Med.Chem_58C_84 |
| Author(s) : Catto M , Berezin AA , Lo Re D , Loizou G , Demetriades M , De Stradis A , Campagna F , Koutentis PA , Carotti A |
| Ref : Eur Journal of Medicinal Chemistry , 58C :84 , 2012 |
| Abstract : Catto_2012_Eur.J.Med.Chem_58C_84 |
| ESTHER : Catto_2012_Eur.J.Med.Chem_58C_84 |
| PubMedSearch : Catto_2012_Eur.J.Med.Chem_58C_84 |
| PubMedID: 23108363 |
| Title : Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases - Pisani_2011_Curr.Med.Chem_18_4568 |
| Author(s) : Pisani L , Catto M , Leonetti F , Nicolotti O , Stefanachi A , Campagna F , Carotti A |
| Ref : Curr Med Chem , 18 :4568 , 2011 |
| Abstract : Pisani_2011_Curr.Med.Chem_18_4568 |
| ESTHER : Pisani_2011_Curr.Med.Chem_18_4568 |
| PubMedSearch : Pisani_2011_Curr.Med.Chem_18_4568 |
| PubMedID: 21864289 |
| Title : Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity - Conejo-Garcia_2011_J.Med.Chem_54_2627 |
| Author(s) : Conejo-Garcia A , Pisani L , Nunez Mdel C , Catto M , Nicolotti O , Leonetti F , Campos JM , Gallo MA , Espinosa A , Carotti A |
| Ref : Journal of Medicinal Chemistry , 54 :2627 , 2011 |
| Abstract : Conejo-Garcia_2011_J.Med.Chem_54_2627 |
| ESTHER : Conejo-Garcia_2011_J.Med.Chem_54_2627 |
| PubMedSearch : Conejo-Garcia_2011_J.Med.Chem_54_2627 |
| PubMedID: 21417225 |
| Title : Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease - Tasso_2011_Eur.J.Med.Chem_46_2170 |
| Author(s) : Tasso B , Catto M , Nicolotti O , Novelli F , Tonelli M , Giangreco I , Pisani L , Sparatore A , Boido V , Carotti A , Sparatore F |
| Ref : Eur Journal of Medicinal Chemistry , 46 :2170 , 2011 |
| Abstract : Tasso_2011_Eur.J.Med.Chem_46_2170 |
| ESTHER : Tasso_2011_Eur.J.Med.Chem_46_2170 |
| PubMedSearch : Tasso_2011_Eur.J.Med.Chem_46_2170 |
| PubMedID: 21459491 |
| Title : Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors - Pisani_2010_ChemMedChem_5_1616 |
| Author(s) : Pisani L , Catto M , Giangreco I , Leonetti F , Nicolotti O , Stefanachi A , Cellamare S , Carotti A |
| Ref : ChemMedChem , 5 :1616 , 2010 |
| Abstract : Pisani_2010_ChemMedChem_5_1616 |
| ESTHER : Pisani_2010_ChemMedChem_5_1616 |
| PubMedSearch : Pisani_2010_ChemMedChem_5_1616 |
| PubMedID: 20677317 |
| Title : Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors - Leonetti_2008_Bioorg.Med.Chem_16_7450 |
| Author(s) : Leonetti F , Catto M , Nicolotti O , Pisani L , Cappa A , Stefanachi A , Carotti A |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7450 , 2008 |
| Abstract : Leonetti_2008_Bioorg.Med.Chem_16_7450 |
| ESTHER : Leonetti_2008_Bioorg.Med.Chem_16_7450 |
| PubMedSearch : Leonetti_2008_Bioorg.Med.Chem_16_7450 |
| PubMedID: 18585045 |
| Title : Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors - Carotti_2006_Bioorg.Med.Chem_14_7205 |
| Author(s) : Carotti A , de Candia M , Catto M , Borisova TN , Varlamov AV , Mendez-Alvarez E , Soto-Otero R , Voskressensky LG , Altomare CD |
| Ref : Bioorganic & Medicinal Chemistry , 14 :7205 , 2006 |
| Abstract : Carotti_2006_Bioorg.Med.Chem_14_7205 |
| ESTHER : Carotti_2006_Bioorg.Med.Chem_14_7205 |
| PubMedSearch : Carotti_2006_Bioorg.Med.Chem_14_7205 |
| PubMedID: 16843666 |
| Title : Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase - Bruhlmann_2001_J.Med.Chem_44_3195 |
| Author(s) : Bruhlmann C , Ooms F , Carrupt PA , Testa B , Catto M , Leonetti F , Altomare CD , Carotti A |
| Ref : Journal of Medicinal Chemistry , 44 :3195 , 2001 |
| Abstract : Bruhlmann_2001_J.Med.Chem_44_3195 |
| ESTHER : Bruhlmann_2001_J.Med.Chem_44_3195 |
| PubMedSearch : Bruhlmann_2001_J.Med.Chem_44_3195 |
| PubMedID: 11543689 |