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| Title : A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models - Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| Author(s) : Ji J , Bunnelle WH , Anderson DJ , Faltynek C , Dyhring T , Ahring PK , Rueter LE , Curzon P , Buckley MJ , Marsh KC , Kempf-Grote A , Meyer MD |
| Ref : Biochemical Pharmacology , 74 :1253 , 2007 |
| Abstract : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| ESTHER : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| PubMedSearch : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| PubMedID: 17854775 |
| Title : ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders - Rueter_2004_CNS.Drug.Rev_10_167 |
| Author(s) : Rueter LE , Anderson DJ , Briggs CA , Donnelly-Roberts D , Gintant GA , Gopalakrishnan M , Lin NH , Osinski MA , Reinhart GA , Buckley MJ , Martin RL , McDermott JS , Preusser LC , Seifert TR , Su Z , Cox BF , Decker MW , Sullivan JP |
| Ref : CNS Drug Rev , 10 :167 , 2004 |
| Abstract : Rueter_2004_CNS.Drug.Rev_10_167 |
| ESTHER : Rueter_2004_CNS.Drug.Rev_10_167 |
| PubMedSearch : Rueter_2004_CNS.Drug.Rev_10_167 |
| PubMedID: 15179445 |
| Title : Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors - Holladay_1998_J.Med.Chem_41_407 |
| Author(s) : Holladay MW , Wasicak JT , Lin NH , He Y , Ryther KB , Bannon AW , Buckley MJ , Kim DJ , Decker MW , Anderson DJ , Campbell JE , Kuntzweiler TA , Donnelly-Roberts D , Piattoni-Kaplan M , Briggs CA , Williams M , Arneric SP |
| Ref : Journal of Medicinal Chemistry , 41 :407 , 1998 |
| Abstract : Holladay_1998_J.Med.Chem_41_407 |
| ESTHER : Holladay_1998_J.Med.Chem_41_407 |
| PubMedSearch : Holladay_1998_J.Med.Chem_41_407 |
| PubMedID: 9484491 |
| Title : ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization - Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| Author(s) : Bannon AW , Decker MW , Curzon P , Buckley MJ , Kim DJ , Radek RJ , Lynch JK , Wasicak JT , Lin NH , Arnold WH , Holladay MW , Williams M , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 285 :787 , 1998 |
| Abstract : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| ESTHER : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| PubMedSearch : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| PubMedID: 9580627 |
| Title : Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice - Decker_1998_Eur.J.Pharmacol_346_23 |
| Author(s) : Decker MW , Bannon AW , Buckley MJ , Kim DJ , Holladay MW , Ryther KB , Lin NH , Wasicak JT , Williams M , Arneric SP |
| Ref : European Journal of Pharmacology , 346 :23 , 1998 |
| Abstract : Decker_1998_Eur.J.Pharmacol_346_23 |
| ESTHER : Decker_1998_Eur.J.Pharmacol_346_23 |
| PubMedSearch : Decker_1998_Eur.J.Pharmacol_346_23 |
| PubMedID: 9617748 |
| Title : Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice - Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| Author(s) : Holladay MW , Bai H , Li Y , Lin NH , Daanen JF , Ryther KB , Wasicak JT , Kincaid JF , He Y , Hettinger AM , Huang P , Anderson DJ , Bannon AW , Buckley MJ , Campbell JE , Donnelly-Roberts D , Gunther KL , Kim DJ , Kuntzweiler TA , Sullivan JP , Decker MW , Arneric SP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :2797 , 1998 |
| Abstract : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| ESTHER : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| PubMedSearch : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| PubMedID: 9873625 |
| Title : Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo - Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| Author(s) : Briggs CA , Anderson DJ , Brioni JD , Buccafusco JJ , Buckley MJ , Campbell JE , Decker MW , Donnelly-Roberts D , Elliott RL , Gopalakrishnan M , Holladay MW , Hui YH , Jackson WJ , Kim DJ , Marsh KC , O'Neill A , Prendergast MA , Ryther KB , Sullivan JP , Arneric SP |
| Ref : Pharmacol Biochem Behav , 57 :231 , 1997 |
| Abstract : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| ESTHER : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| PubMedSearch : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| PubMedID: 9164577 |
| Title : Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties - Lin_1997_J.Med.Chem_40_385 |
| Author(s) : Lin NH , Gunn DE , Ryther KB , Garvey DS , Donnelly-Roberts D , Decker MW , Brioni JD , Buckley MJ , Rodrigues AD , Marsh KG , Anderson DJ , Buccafusco JJ , Prendergast MA , Sullivan JP , Williams M , Arneric SP , Holladay MW |
| Ref : Journal of Medicinal Chemistry , 40 :385 , 1997 |
| Abstract : Lin_1997_J.Med.Chem_40_385 |
| ESTHER : Lin_1997_J.Med.Chem_40_385 |
| PubMedSearch : Lin_1997_J.Med.Chem_40_385 |
| PubMedID: 9022806 |
| Title : (+\/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors - Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| Author(s) : Sullivan JP , Decker MW , Brioni JD , Donnelly-Roberts D , Anderson DJ , Bannon AW , Kang CH , Adams P , Piattoni-Kaplan M , Buckley MJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 271 :624 , 1994 |
| Abstract : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| ESTHER : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| PubMedSearch : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| PubMedID: 7965777 |
| Title : Novel isoxazoles which interact with brain cholinergic channel receptors have intrinsic cognitive enhancing and anxiolytic activities - |
| Author(s) : Garvey DS , Wasicak JT , Decker MW , Brioni JD , Buckley MJ , Sullivan JP , Carrera GM , Holladay MW , Arneric SP , Williams M |
| Ref : Journal of Medicinal Chemistry , 37 :1055 , 1994 |
| PubMedID: 7909335 |