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Title : From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease - Brown_2021_Cell_184_5886 |
Author(s) : Brown AJH , Bradley SJ , Marshall FH , Brown GA , Bennett KA , Brown J , Cansfield JE , Cross DM , de Graaf C , Hudson BD , Dwomoh L , Dias JM , Errey JC , Hurrell E , Liptrot J , Mattedi G , Molloy C , Nathan PJ , Okrasa K , Osborne G , Patel JC , Pickworth M , Robertson N , Shahabi S , Bundgaard C , Phillips K , Broad LM , Goonawardena AV , Morairty SR , Browning M , Perini F , Dawson GR , Deakin JFW , Smith RT , Sexton PM , Warneck J , Vinson M , Tasker T , Tehan BG , Teobald B , Christopoulos A , Langmead CJ , Jazayeri A , Cooke RM , Rucktooa P , Congreve MS , Weir M , Tobin AB |
Ref : Cell , 184 :5886 , 2021 |
Abstract : Brown_2021_Cell_184_5886 |
ESTHER : Brown_2021_Cell_184_5886 |
PubMedSearch : Brown_2021_Cell_184_5886 |
PubMedID: 34822784 |
Title : Potentiation of analgesic efficacy but not side effects: co-administration of an alpha4beta2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats - Zhu_2011_Biochem.Pharmacol_82(8)_967 |
Author(s) : Zhu CZ , Chin CL , Rustay NR , Zhong C , Mikusa J , Chandran P , Salyers A , Gomez E , Simler G , Lewis LG , Gauvin D , Baker S , Pai M , Tovcimak A , Brown J , Komater V , Fox GB , Decker MW , Jacobson PB , Gopalakrishnan M , Lee CH , Honore P |
Ref : Biochemical Pharmacology , 82 :967 , 2011 |
Abstract : Zhu_2011_Biochem.Pharmacol_82(8)_967 |
ESTHER : Zhu_2011_Biochem.Pharmacol_82(8)_967 |
PubMedSearch : Zhu_2011_Biochem.Pharmacol_82(8)_967 |
PubMedID: 21620806 |
Title : Poster: In vivo characterization of the co-administration of alpha4\/beta2 neuronal nicotinic receptor agonist and positive allosteric modulator in experimental pain in rats - |
Author(s) : Zhu CZ , Chin C-l , Zhong C , Mikusa J , Chandran P , Salyers A , Wensink E , Silmer G , Lewis LG , Gauvin D , Baker S , Tovcimak A , Brown J , Rustay N , Fox GB , Decker MW , Lee C-H , Gopalakrishnan M , Honore P |
Ref : Biochemical Pharmacology , 78 :920 , 2009 |
PubMedID: |
Title : Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B\/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide) - Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
Author(s) : Dunlop J , Lock T , Jow B , Sitzia F , Grauer S , Jow F , Kramer A , Bowlby MR , Randall A , Kowal D , Gilbert A , Comery TA , Larocque J , Soloveva V , Brown J , Roncarati R |
Ref : Journal of Pharmacology & Experimental Therapeutics , 328 :766 , 2009 |
Abstract : Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
ESTHER : Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
PubMedSearch : Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
PubMedID: 19050173 |
Title : Cloning, Characterization, Controlled Overexpression, and Inactivation of the Major Tributyrin Esterase Gene of Lactococcus lactis. - |
Author(s) : Fernandez L , Beerthuyzen MM , Brown J , Siezen RJ , Coolbear T , Holland R , Kuipers OP |
Ref : Applied Environmental Microbiology , 66 :1360 , 2000 |
PubMedID: 10742212 |
Gene_locus related to this paper: lacla-ESTA |
Title : SCH 57790: a novel M2 receptor selective antagonist - Lachowicz_1999_Life.Sci_64(6-7)_535 |
Author(s) : Lachowicz JE , Lowe D , Duffy RA , Ruperto V , Taylor LA , Guzik H , Brown J , Berger JG , Tice M , McQuade R , Kozlowski J , Clader J , Strader CD , Murgolo N |
Ref : Life Sciences , 64 :535 , 1999 |
Abstract : Lachowicz_1999_Life.Sci_64(6-7)_535 |
ESTHER : Lachowicz_1999_Life.Sci_64(6-7)_535 |
PubMedSearch : Lachowicz_1999_Life.Sci_64(6-7)_535 |
PubMedID: 10069520 |
Title : Lumenal location of the microsomal beta-glucuronidase-egasyn complex - Brown_1987_J.Cell.Biol_105_1571 |
Author(s) : Brown J , Novak EK , Takeuchi K , Moore K , Medda S , Swank RT |
Ref : Journal of Cell Biology , 105 :1571 , 1987 |
Abstract : Brown_1987_J.Cell.Biol_105_1571 |
ESTHER : Brown_1987_J.Cell.Biol_105_1571 |
PubMedSearch : Brown_1987_J.Cell.Biol_105_1571 |
PubMedID: 3667691 |
Gene_locus related to this paper: human-CES1 |