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| Title : Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17 - Chrast_2019_Microorganisms_7_ |
| Author(s) : Chrast L , Tratsiak K , Planas-Iglesias J , Daniel L , Prudnikova T , Brezovsky J , Bednar D , Kuta Smatanova I , Chaloupkova R , Damborsky J |
| Ref : Microorganisms , 7 : , 2019 |
| Abstract : Chrast_2019_Microorganisms_7_ |
| ESTHER : Chrast_2019_Microorganisms_7_ |
| PubMedSearch : Chrast_2019_Microorganisms_7_ |
| PubMedID: 31661858 |
| Gene_locus related to this paper: 9alte-a3jb27 |
| Title : Impact of the access tunnel engineering on catalysis is strictly ligand-specific - Kaushik_2018_FEBS.J_285_1456 |
| Author(s) : Kaushik S , Marques SM , Khirsariya P , Paruch K , Libichova L , Brezovsky J , Prokop Z , Chaloupkova R , Damborsky J |
| Ref : Febs J , 285 :1456 , 2018 |
| Abstract : Kaushik_2018_FEBS.J_285_1456 |
| ESTHER : Kaushik_2018_FEBS.J_285_1456 |
| PubMedSearch : Kaushik_2018_FEBS.J_285_1456 |
| PubMedID: 29478278 |
| Title : Ancestral Haloalkane Dehalogenases Show Robustness and Unique Substrate Specificity - Babkova_2017_Chembiochem_18_1448 |
| Author(s) : Babkova P , Sebestova E , Brezovsky J , Chaloupkova R , Damborsky J |
| Ref : Chembiochem , 18 :1448 , 2017 |
| Abstract : Babkova_2017_Chembiochem_18_1448 |
| ESTHER : Babkova_2017_Chembiochem_18_1448 |
| PubMedSearch : Babkova_2017_Chembiochem_18_1448 |
| PubMedID: 28419658 |
| Gene_locus related to this paper: 9bact-AncHLD5 |
| Title : Different Structural Origins of the Enantioselectivity of Haloalkane Dehalogenases toward Linear beta-Haloalkanes: Open-Solvated versus Occluded-Desolvated Active Sites - Liskova_2017_Angew.Chem.Int.Ed.Engl_56_4719 |
| Author(s) : Liskova V , Stepankova V , Bednar D , Brezovsky J , Prokop Z , Chaloupkova R , Damborsky J |
| Ref : Angew Chem Int Ed Engl , 56 :4719 , 2017 |
| Abstract : Liskova_2017_Angew.Chem.Int.Ed.Engl_56_4719 |
| ESTHER : Liskova_2017_Angew.Chem.Int.Ed.Engl_56_4719 |
| PubMedSearch : Liskova_2017_Angew.Chem.Int.Ed.Engl_56_4719 |
| PubMedID: 28334478 |
| Title : Catalytic Cycle of Haloalkane Dehalogenases Toward Unnatural Substrates Explored by Computational Modeling - Marques_2017_J.Chem.Inf.Model_57_1970 |
| Author(s) : Marques SM , Dunajova Z , Prokop Z , Chaloupkova R , Brezovsky J , Damborsky J |
| Ref : J Chem Inf Model , 57 :1970 , 2017 |
| Abstract : Marques_2017_J.Chem.Inf.Model_57_1970 |
| ESTHER : Marques_2017_J.Chem.Inf.Model_57_1970 |
| PubMedSearch : Marques_2017_J.Chem.Inf.Model_57_1970 |
| PubMedID: 28696117 |
| Title : Engineering a de novo transport tunnel - Brezovsky_2016_ACS.Catal_6_7597 |
| Author(s) : Brezovsky J , Babkova P , Degtjarik O , Fortova A , Gora A , Iermak I , Rezacova P , Dvorak P , Kuta-Smatanova I , Prokop Z , Chaloupkova R , Damborsky J |
| Ref : ACS Catal , 6 :7597 , 2016 |
| Abstract : Brezovsky_2016_ACS.Catal_6_7597 |
| ESTHER : Brezovsky_2016_ACS.Catal_6_7597 |
| PubMedSearch : Brezovsky_2016_ACS.Catal_6_7597 |
| PubMedID: |
| Gene_locus related to this paper: sphpi-linb |
| Title : Discovery of Novel Haloalkane Dehalogenase Inhibitors - Buryska_2016_Appl.Environ.Microbiol_82_1958 |
| Author(s) : Buryska T , Daniel L , Kunka A , Brezovsky J , Damborsky J , Prokop Z |
| Ref : Applied Environmental Microbiology , 82 :1958 , 2016 |
| Abstract : Buryska_2016_Appl.Environ.Microbiol_82_1958 |
| ESTHER : Buryska_2016_Appl.Environ.Microbiol_82_1958 |
| PubMedSearch : Buryska_2016_Appl.Environ.Microbiol_82_1958 |
| PubMedID: 26773086 |
| Title : Mechanism-based discovery of novel substrates of haloalkane dehalogenases using in silico screening - Daniel_2015_J.Chem.Inf.Model_55_54 |
| Author(s) : Daniel L , Buryska T , Prokop Z , Damborsky J , Brezovsky J |
| Ref : J Chem Inf Model , 55 :54 , 2015 |
| Abstract : Daniel_2015_J.Chem.Inf.Model_55_54 |
| ESTHER : Daniel_2015_J.Chem.Inf.Model_55_54 |
| PubMedSearch : Daniel_2015_J.Chem.Inf.Model_55_54 |
| PubMedID: 25495415 |
| Title : Site-specific analysis of protein hydration based on unnatural amino acid fluorescence - Amaro_2015_J.Am.Chem.Soc_137_4988 |
| Author(s) : Amaro M , Brezovsky J , Kovacova S , Sykora J , Bednar D , Nemec V , Liskova V , Kurumbang NP , Beerens K , Chaloupkova R , Paruch K , Hof M , Damborsky J |
| Ref : Journal of the American Chemical Society , 137 :4988 , 2015 |
| Abstract : Amaro_2015_J.Am.Chem.Soc_137_4988 |
| ESTHER : Amaro_2015_J.Am.Chem.Soc_137_4988 |
| PubMedSearch : Amaro_2015_J.Am.Chem.Soc_137_4988 |
| PubMedID: 25815779 |
| Title : FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants - Bednar_2015_PLoS.Comput.Biol_11_e1004556 |
| Author(s) : Bednar D , Beerens K , Sebestova E , Bendl J , Khare S , Chaloupkova R , Prokop Z , Brezovsky J , Baker D , Damborsky J |
| Ref : PLoS Comput Biol , 11 :e1004556 , 2015 |
| Abstract : Bednar_2015_PLoS.Comput.Biol_11_e1004556 |
| ESTHER : Bednar_2015_PLoS.Comput.Biol_11_e1004556 |
| PubMedSearch : Bednar_2015_PLoS.Comput.Biol_11_e1004556 |
| PubMedID: 26529612 |
| Gene_locus related to this paper: rhoso-halo1 |
| Title : Balancing the stability-activity trade-off by fine-tuning dehalogenase access tunnels - Liskova_2015_ChemCatChem_7_648 |
| Author(s) : Liskova V , Bednar D , Prudnikova T , Rezacova P , Koudelakova T , Sebestova E , Kuta-Smatanova I , Brezovsky J , Chaloupkova R , Damborsky J |
| Ref : ChemCatChem , 7 :648 , 2015 |
| Abstract : Liskova_2015_ChemCatChem_7_648 |
| ESTHER : Liskova_2015_ChemCatChem_7_648 |
| PubMedSearch : Liskova_2015_ChemCatChem_7_648 |
| PubMedID: |
| Gene_locus related to this paper: rhoso-halo1 |
| Title : Dynamics and hydration explain failed functional transformation in dehalogenase design - Sykora_2014_Nat.Chem.Biol_10_428 |
| Author(s) : Sykora J , Brezovsky J , Koudelakova T , Lahoda M , Fortova A , Chernovets T , Chaloupkova R , Stepankova V , Prokop Z , Smatanova IK , Hof M , Damborsky J |
| Ref : Nat Chemical Biology , 10 :428 , 2014 |
| Abstract : Sykora_2014_Nat.Chem.Biol_10_428 |
| ESTHER : Sykora_2014_Nat.Chem.Biol_10_428 |
| PubMedSearch : Sykora_2014_Nat.Chem.Biol_10_428 |
| PubMedID: 24727901 |
| Gene_locus related to this paper: rhoso-halo1 |
| Title : Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites - Chaloupkova_2014_Acta.Crystallogr.D.Biol.Crystallogr_70_1884 |
| Author(s) : Chaloupkova R , Prudnikova T , Rezacova P , Prokop Z , Koudelakova T , Daniel L , Brezovsky J , Ikeda-Ohtsubo W4 , Sato Y , Kuty M , Nagata Y , Kuta Smatanova I , Damborsky J |
| Ref : Acta Crystallographica D Biol Crystallogr , 70 :1884 , 2014 |
| Abstract : Chaloupkova_2014_Acta.Crystallogr.D.Biol.Crystallogr_70_1884 |
| ESTHER : Chaloupkova_2014_Acta.Crystallogr.D.Biol.Crystallogr_70_1884 |
| PubMedSearch : Chaloupkova_2014_Acta.Crystallogr.D.Biol.Crystallogr_70_1884 |
| PubMedID: 25004965 |
| Gene_locus related to this paper: brael-e2rv62 |
| Title : The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 - Hasan_2013_FEBS.J_280_3149 |
| Author(s) : Hasan K , Gora A , Brezovsky J , Chaloupkova R , Moskalikova H , Fortova A , Nagata Y , Damborsky J , Prokop Z |
| Ref : Febs J , 280 :3149 , 2013 |
| Abstract : Hasan_2013_FEBS.J_280_3149 |
| ESTHER : Hasan_2013_FEBS.J_280_3149 |
| PubMedSearch : Hasan_2013_FEBS.J_280_3149 |
| PubMedID: 23490078 |
| Title : Are time-dependent fluorescence shifts at the tunnel mouth of haloalkane dehalogenase enzymes dependent on the choice of the chromophore? - Amaro_2013_J.Phys.Chem.B_117_7898 |
| Author(s) : Amaro M , Brezovsky J , Kovacova S , Maier L , Chaloupkova R , Sykora J , Paruch K , Damborsky J , Hof M |
| Ref : J Phys Chem B , 117 :7898 , 2013 |
| Abstract : Amaro_2013_J.Phys.Chem.B_117_7898 |
| ESTHER : Amaro_2013_J.Phys.Chem.B_117_7898 |
| PubMedSearch : Amaro_2013_J.Phys.Chem.B_117_7898 |
| PubMedID: 23781851 |
| Title : Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel - Koudelakova_2013_Angew.Chem.Int.Ed.Engl_52_1959 |
| Author(s) : Koudelakova T , Chaloupkova R , Brezovsky J , Prokop Z , Sebestova E , Hesseler M , Khabiri M , Plevaka M , Kulik D , Kuta Smatanova I , Rezacova P , Ettrich R , Bornscheuer UT , Damborsky J |
| Ref : Angew Chem Int Ed Engl , 52 :1959 , 2013 |
| Abstract : Koudelakova_2013_Angew.Chem.Int.Ed.Engl_52_1959 |
| ESTHER : Koudelakova_2013_Angew.Chem.Int.Ed.Engl_52_1959 |
| PubMedSearch : Koudelakova_2013_Angew.Chem.Int.Ed.Engl_52_1959 |
| PubMedID: 23303607 |
| Gene_locus related to this paper: rhoso-halo1 |
| Title : Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents - Stepankova_2013_Chembiochem_14_890 |
| Author(s) : Stepankova V , Khabiri M , Brezovsky J , Pavelka A , Sykora J , Amaro M , Minofar B , Prokop Z , Hof M , Ettrich R , Chaloupkova R , Damborsky J |
| Ref : Chembiochem , 14 :890 , 2013 |
| Abstract : Stepankova_2013_Chembiochem_14_890 |
| ESTHER : Stepankova_2013_Chembiochem_14_890 |
| PubMedSearch : Stepankova_2013_Chembiochem_14_890 |
| PubMedID: 23564727 |
| Gene_locus related to this paper: rhoso-halo1 |
| Title : Interaction of organic solvents with protein structures at protein-solvent interface - Khabiri_2013_J.Mol.Model_19_4701 |
| Author(s) : Khabiri M , Minofar B , Brezovsky J , Damborsky J , Ettrich R |
| Ref : J Mol Model , 19 :4701 , 2013 |
| Abstract : Khabiri_2013_J.Mol.Model_19_4701 |
| ESTHER : Khabiri_2013_J.Mol.Model_19_4701 |
| PubMedSearch : Khabiri_2013_J.Mol.Model_19_4701 |
| PubMedID: 22760789 |
| Title : Substrate specificity of haloalkane dehalogenases - Koudelakova_2011_Biochem.J_435_345 |
| Author(s) : Koudelakova T , Chovancova E , Brezovsky J , Monincova M , Fortova A , Jarkovsky J , Damborsky J |
| Ref : Biochemical Journal , 435 :345 , 2011 |
| Abstract : Koudelakova_2011_Biochem.J_435_345 |
| ESTHER : Koudelakova_2011_Biochem.J_435_345 |
| PubMedSearch : Koudelakova_2011_Biochem.J_435_345 |
| PubMedID: 21294712 |
| Gene_locus related to this paper: agrtu-DHAA , brael-e2rv62 , braja-dhaa , myctu-linb , myctu-Rv1833c , rhoba-DHLA , rhoso-halo1 , sphpi-linb , xanau-halo1 |
| Title : Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering - |
| Author(s) : Prokop Z , Sato Y , Brezovsky J , Mozga T , Chaloupkova R , Koudelakova T , Jerabek P , Stepankova V , Natsume R , van Leeuwen JG , Janssen DB , Florian J , Nagata Y , Senda T , Damborsky J |
| Ref : Angew Chem Int Ed Engl , 49 :6111 , 2010 |
| PubMedID: 20645368 |
| Gene_locus related to this paper: braja-dhaa |
| Title : Computational tools for designing and engineering biocatalysts - Damborsky_2009_Curr.Opin.Chem.Biol_13_26 |
| Author(s) : Damborsky J , Brezovsky J |
| Ref : Curr Opin Chemical Biology , 13 :26 , 2009 |
| Abstract : Damborsky_2009_Curr.Opin.Chem.Biol_13_26 |
| ESTHER : Damborsky_2009_Curr.Opin.Chem.Biol_13_26 |
| PubMedSearch : Damborsky_2009_Curr.Opin.Chem.Biol_13_26 |
| PubMedID: 19297237 |
| Title : Nanosecond time-dependent Stokes shift at the tunnel mouth of haloalkane dehalogenases - Jesenska_2009_J.Am.Chem.Soc_131_494 |
| Author(s) : Jesenska A , Sykora J , Olzynska A , Brezovsky J , Zdrahal Z , Damborsky J , Hof M |
| Ref : Journal of the American Chemical Society , 131 :494 , 2009 |
| Abstract : Jesenska_2009_J.Am.Chem.Soc_131_494 |
| ESTHER : Jesenska_2009_J.Am.Chem.Soc_131_494 |
| PubMedSearch : Jesenska_2009_J.Am.Chem.Soc_131_494 |
| PubMedID: 19113888 |