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| Title : Donecopride, a Swiss army knife with potential against Alzheimer's disease - Rochais_2020_Br.J.Pharmacol_177_1988 |
| Author(s) : Rochais C , Lecoutey C , Hamidouche K , Giannoni P , Gaven F , Cem E , Mignani S , Baranger K , Freret T , Bockaert J , Rivera S , Boulouard M , Dallemagne P , Claeysen S |
| Ref : British Journal of Pharmacology , 177 :1988 , 2020 |
| Abstract : Rochais_2020_Br.J.Pharmacol_177_1988 |
| ESTHER : Rochais_2020_Br.J.Pharmacol_177_1988 |
| PubMedSearch : Rochais_2020_Br.J.Pharmacol_177_1988 |
| PubMedID: 31881553 |
| Title : Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT(6) receptor antagonist with therapeutic interest in Alzheimer's disease - Toublet_2020_Eur.J.Med.Chem_210_113059 |
| Author(s) : Toublet FX , Lalut J , Hatat B , Lecoutey C , Davis A , Since M , Corvaisier S , Freret T , Sopkova-de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 210 :113059 , 2020 |
| Abstract : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| ESTHER : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| PubMedSearch : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| PubMedID: 33310288 |
| Title : A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer's Disease - Hatat_2019_Front.Aging.Neurosci_11_148 |
| Author(s) : Hatat B , Yahiaoui S , Lecoutey C , Davis A , Freret T , Boulouard M , Claeysen S , Rochais C , Dallemagne P |
| Ref : Front Aging Neurosci , 11 :148 , 2019 |
| Abstract : Hatat_2019_Front.Aging.Neurosci_11_148 |
| ESTHER : Hatat_2019_Front.Aging.Neurosci_11_148 |
| PubMedSearch : Hatat_2019_Front.Aging.Neurosci_11_148 |
| PubMedID: 31316368 |
| Title : Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease - Toublet_2019_Molecules_24_ |
| Author(s) : Toublet FX , Lecoutey C , Lalut J , Hatat B , Davis A , Since M , Corvaisier S , Freret T , Sopkova de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Molecules , 24 : , 2019 |
| Abstract : Toublet_2019_Molecules_24_ |
| ESTHER : Toublet_2019_Molecules_24_ |
| PubMedSearch : Toublet_2019_Molecules_24_ |
| PubMedID: 31370232 |
| Title : Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse - Freret_2017_Psychopharmacology.(Berl)_234_2365 |
| Author(s) : Freret T , Lelong-Boulouard V , Lecouflet P , Hamidouche K , Dauphin F , Boulouard M |
| Ref : Psychopharmacology (Berl) , 234 :2365 , 2017 |
| Abstract : Freret_2017_Psychopharmacology.(Berl)_234_2365 |
| ESTHER : Freret_2017_Psychopharmacology.(Berl)_234_2365 |
| PubMedSearch : Freret_2017_Psychopharmacology.(Berl)_234_2365 |
| PubMedID: 28631100 |
| Title : Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease - Yahiaoui_2016_Eur.J.Med.Chem_121_283 |
| Author(s) : Yahiaoui S , Hamidouche K , Ballandonne C , Davis A , de Oliveira Santos JS , Freret T , Boulouard M , Rochais C , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 121 :283 , 2016 |
| Abstract : Yahiaoui_2016_Eur.J.Med.Chem_121_283 |
| ESTHER : Yahiaoui_2016_Eur.J.Med.Chem_121_283 |
| PubMedSearch : Yahiaoui_2016_Eur.J.Med.Chem_121_283 |
| PubMedID: 27266998 |
| Title : Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride - Rochais_2015_J.Med.Chem_58_3172 |
| Author(s) : Rochais C , Lecoutey C , Gaven F , Giannoni P , Hamidouche K , Hedou D , Dubost E , Genest D , Yahiaoui S , Freret T , Bouet V , Dauphin F , Sopkova de Oliveira Santos J , Ballandonne C , Corvaisier S , Malzert-Freon A , Legay R , Boulouard M , Claeysen S , Dallemagne P |
| Ref : Journal of Medicinal Chemistry , 58 :3172 , 2015 |
| Abstract : Rochais_2015_J.Med.Chem_58_3172 |
| ESTHER : Rochais_2015_J.Med.Chem_58_3172 |
| PubMedSearch : Rochais_2015_J.Med.Chem_58_3172 |
| PubMedID: 25793650 |
| Title : Therapeutic Potential of 5-HT6 Receptor Agonists - Karila_2015_J.Med.Chem_58_7901 |
| Author(s) : Karila D , Freret T , Bouet V , Boulouard M , Dallemagne P , Rochais C |
| Ref : Journal of Medicinal Chemistry , 58 :7901 , 2015 |
| Abstract : Karila_2015_J.Med.Chem_58_7901 |
| ESTHER : Karila_2015_J.Med.Chem_58_7901 |
| PubMedSearch : Karila_2015_J.Med.Chem_58_7901 |
| PubMedID: 26099069 |
| Title : Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances - Quiedeville_2015_Behav.Brain.Res_293_10 |
| Author(s) : Quiedeville A , Boulouard M , Hamidouche K , Da Silva Costa-Aze V , Nee G , Rochais C , Dallemagne P , Fabis F , Freret T , Bouet V |
| Ref : Behavioural Brain Research , 293 :10 , 2015 |
| Abstract : Quiedeville_2015_Behav.Brain.Res_293_10 |
| ESTHER : Quiedeville_2015_Behav.Brain.Res_293_10 |
| PubMedSearch : Quiedeville_2015_Behav.Brain.Res_293_10 |
| PubMedID: 26187692 |
| Title : Design of donecopride, a dual serotonin subtype 4 receptor agonist\/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment - Lecoutey_2014_Proc.Natl.Acad.Sci.U.S.A_111_E3825 |
| Author(s) : Lecoutey C , Hedou D , Freret T , Giannoni P , Gaven F , Since M , Bouet V , Ballandonne C , Corvaisier S , Malzert Freon A , Mignani S , Cresteil T , Boulouard M , Claeysen S , Rochais C , Dallemagne P |
| Ref : Proc Natl Acad Sci U S A , 111 :E3825 , 2014 |
| Abstract : Lecoutey_2014_Proc.Natl.Acad.Sci.U.S.A_111_E3825 |
| ESTHER : Lecoutey_2014_Proc.Natl.Acad.Sci.U.S.A_111_E3825 |
| PubMedSearch : Lecoutey_2014_Proc.Natl.Acad.Sci.U.S.A_111_E3825 |
| PubMedID: 25157130 |
| Title : Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice - Freret_2012_Behav.Brain.Res_230_304 |
| Author(s) : Freret T , Bouet V , Quiedeville A , Nee G , Dallemagne P , Rochais C , Boulouard M |
| Ref : Behavioural Brain Research , 230 :304 , 2012 |
| Abstract : Freret_2012_Behav.Brain.Res_230_304 |
| ESTHER : Freret_2012_Behav.Brain.Res_230_304 |
| PubMedSearch : Freret_2012_Behav.Brain.Res_230_304 |
| PubMedID: 22348892 |
| Title : Synthesis and preliminary in vivo evaluation of new 2-Aryl-6-methyl-1,2-dihydro-1H-pyridin-4-ones and 2-Aryl-6-methylpiperidin-4-ols, as potential anti-amnesiant agents - Leflemme_2005_J.Enzyme.Inhib.Med.Chem_20_551 |
| Author(s) : Leflemme N , Freret T , Boulouard M , Dallemagne P , Rault S |
| Ref : J Enzyme Inhib Med Chem , 20 :551 , 2005 |
| Abstract : Leflemme_2005_J.Enzyme.Inhib.Med.Chem_20_551 |
| ESTHER : Leflemme_2005_J.Enzyme.Inhib.Med.Chem_20_551 |
| PubMedSearch : Leflemme_2005_J.Enzyme.Inhib.Med.Chem_20_551 |
| PubMedID: 16408790 |
| Title : Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil - Omran_2005_Eur.J.Med.Chem_40_1222 |
| Author(s) : Omran Z , Cailly T , Lescot E , Santos JS , Agondanou JH , Lisowski V , Fabis F , Godard AM , Stiebing S , Le Flem G , Boulouard M , Dauphin F , Dallemagne P , Rault S |
| Ref : Eur Journal of Medicinal Chemistry , 40 :1222 , 2005 |
| Abstract : Omran_2005_Eur.J.Med.Chem_40_1222 |
| ESTHER : Omran_2005_Eur.J.Med.Chem_40_1222 |
| PubMedSearch : Omran_2005_Eur.J.Med.Chem_40_1222 |
| PubMedID: 16137794 |