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Author Report for: Bosak A

Contact information:

Bosak Anita
Institute for Medical Research and Occupational Health; Ksaverska cesta 2; HR-10000 Zagreb
Phone : +38514673188 +38514682551
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Send E-Mail to Bosak Anita

    Title: Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease
    Matosevic A, Opsenica DM, Spasic M, Marakovic N, Zandona A, Zunec S, Bartolic M, Kovarik Z, Bosak A
    Ref: Chemico-Biological Interactions, 382:110620, 2023 : PubMed


    Title: 4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer's Disease
    Komatovic K, Matosevic A, Terzic-Jovanovic N, Zunec S, Segan S, Zlatovic M, Marakovic N, Bosak A, Opsenica DM
    Ref: Pharmaceutics, 14:, 2022 : PubMed


    Title: Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease
    Matosevic A, Knezevic A, Zandona A, Marakovic N, Kovarik Z, Bosak A
    Ref: Pharmaceuticals (Basel), 15:, 2022 : PubMed


    Title: Synthesis, Biological Evaluation and Machine Learning Prediction Model for Fluorinated Cinchona Alkaloid-Based Derivatives as Cholinesterase Inhibitors
    Ramic A, Matosevic A, Debanic B, Mikelic A, Primozic I, Bosak A, Hrenar T
    Ref: Pharmaceuticals (Basel), 15:, 2022 : PubMed


    Title: Quinuclidine-Based Carbamates as Potential CNS Active Compounds
    Matosevic A, Radman Kastelic A, Mikelic A, Zandona A, Katalinic M, Primozic I, Bosak A, Hrenar T
    Ref: Pharmaceutics, 13:, 2021 : PubMed


    Title: Interactions of Paraoxonase-1 with Pharmacologically Relevant Carbamates
    Bosak A, Bavec A, Konte T, Sinko G, Kovarik Z, Golicnik M
    Ref: Molecules, 25:, 2020 : PubMed


    Title: Structural isomers of saligenin-based beta2-agonists: synthesis and insight into the reaction mechanism
    Knezevic A, Novak J, Bosak A, Vinkovic M
    Ref: Org Biomol Chem, 18:9675, 2020 : PubMed


    Title: Carbamate group as structural motif in drugs: a review of carbamate derivatives used as therapeutic agents
    Matosevic A, Bosak A
    Ref: Arh Hig Rada Toksikol, 71:285, 2020 : PubMed


    Title: Structural aspects of 4-aminoquinolines as reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase
    Bosak A, Opsenica DM, Sinko G, Zlatar M, Kovarik Z
    Ref: Chemico-Biological Interactions, 308:101, 2019 : PubMed


    Title: Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold
    Bosak A, Ramic A, Smidlehner T, Hrenar T, Primozic I, Kovarik Z
    Ref: PLoS ONE, 13:e0205193, 2018 : PubMed


    Title: Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations
    Katalinic M, Sinko G, Macek Hrvat N, Zorbaz T, Bosak A, Kovarik Z
    Ref: Toxicology, 406-407:104, 2018 : PubMed


    Title: Resorcinol-, catechol- and saligenin-based bronchodilating beta2-agonists as inhibitors of human cholinesterase activity
    Bosak A, Knezevic A, Gazic Smilovic I, Sinko G, Kovarik Z
    Ref: J Enzyme Inhib Med Chem, 32:789, 2017 : PubMed


    Title: Peripheral site and acyl pocket define selective inhibition of mouse butyrylcholinesterase by two biscarbamates
    Bosak A, Smilovic IG, Stimac A, Vinkovic V, Sinko G, Kovarik Z
    Ref: Archives of Biochemistry & Biophysics, 529:140, 2013 : PubMed


    Title: Metaproterenol, isoproterenol, and their bisdimethylcarbamate derivatives as human cholinesterase inhibitors
    Bosak A, Gazic Smilovic I, Sinko G, Vinkovic V, Kovarik Z
    Ref: Journal of Medicinal Chemistry, 55:6716, 2012 : PubMed


    Title: [Cholinesterases: structure, role, and inhibition]
    Bosak A, Katalinic M, Kovarik Z
    Ref: Arh Hig Rada Toksikol, 62:175, 2011 : PubMed


    Title: Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol
    Bosak A, Gazic I, Vinkovic V, Kovarik Z
    Ref: Archives of Biochemistry & Biophysics, 471:72, 2008 : PubMed


    Title: Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers
    Bosak A, Gazic I, Vinkovic V, Kovarik Z
    Ref: Chemico-Biological Interactions, 175:192, 2008 : PubMed


    Title: Differentiation of EDTA-sensitive from EDTA-insensitive human serum esterases hydrolysing phenylacetate
    Bosak A, Barlovic-Tusek B, Reiner E
    Ref: J Enzyme Inhib Med Chem, 23:521, 2008 : PubMed


    Title: Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases
    Calic M, Bosak A, Kuca K, Kovarik Z
    Ref: Chemico-Biological Interactions, 175:305, 2008 : PubMed


    Title: Preparative HPLC separation of bambuterol enantiomers and stereoselective inhibition of human cholinesterases
    Gazic I, Bosak A, Sinko G, Vinkovic V, Kovarik Z
    Ref: Anal Bioanal Chem, 385:1513, 2008 : PubMed


    Title: Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning
    Kovarik Z, Calic M, Sinko G, Bosak A, Berend S, Vrdoljak AL, Radic B
    Ref: Chemico-Biological Interactions, 175:173, 2008 : PubMed


    Title: Structure-activity approach in the reactivation of tabun-phosphorylated human acetylcholinesterase with bispyridinium para-aldoximes
    Kovarik Z, Calic M, Sinko G, Bosak A
    Ref: Arh Hig Rada Toksikol, 58:201, 2007 : PubMed


    Title: Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes
    Sinko G, Calic M, Bosak A, Kovarik Z
    Ref: Analytical Biochemistry, 370:223, 2007 : PubMed


    Title: [Organophosphorus compounds: classification and enzyme reactions]
    Bosak A
    Ref: Arh Hig Rada Toksikol, 57:445, 2006 : PubMed


    Title: Preparation of enantiomers of quinuclidin-3-Ol derivatives and their interactions with human cholinesterases
    Simeon-Rudolf V, Tomic S, Bosak A, Primozic I, Orsulic M
    Ref: Chemico-Biological Interactions, 157-158:420, 2005 : PubMed


    Title: Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups
    Sinko G, Bosak A, Kovarik Z, Simeon-Rudolf V
    Ref: Chemico-Biological Interactions, 157-158:421, 2005 : PubMed


    Title: Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine
    Reiner E, Sinko G, Bosak A, Simeon-Rudolf V, Radic Z, Taylor P, Stojan J, Golicnik M
    Ref: In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects, (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina:187 , 2004 : PubMed


    Title: Activity of cholinesterases in human whole blood measured with acetylthiocholine as substrate and ethopropazine as selective inhibitor of plasma butyrylcholinesterase
    Reiner E, Bosak A, Simeon-Rudolf V
    Ref: Arh Hig Rada Toksikol, 55:1, 2004 : PubMed


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