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| Title : Mixed Alkyl\/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets - Bennett_2024_bioRxiv__ |
| Author(s) : Bennett JM , Narwal SK , Kabeche S , Abegg D , Hackett F , Yeo T , Li VL , Muir RK , Faucher FF , Lovell S , Blackman MJ , Adibekian A , Yeh E , Fidock DA , Bogyo M |
| Ref : Biorxiv , : , 2024 |
| Abstract : Bennett_2024_bioRxiv__ |
| ESTHER : Bennett_2024_bioRxiv__ |
| PubMedSearch : Bennett_2024_bioRxiv__ |
| PubMedID: 38260474 |
| Title : Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections - Jo_2024_J.Am.Chem.Soc__ |
| Author(s) : Jo J , Upadhyay T , Woods EC , Park KW , Pedowitz NJ , Jaworek-Korjakowska J , Wang S , Valdez TA , Fellner M , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2024 |
| Abstract : Jo_2024_J.Am.Chem.Soc__ |
| ESTHER : Jo_2024_J.Am.Chem.Soc__ |
| PubMedSearch : Jo_2024_J.Am.Chem.Soc__ |
| PubMedID: 38411555 |
| Gene_locus related to this paper: staau-SA2367 |
| Title : Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron - Keller_2023_Nat.Chem.Biol__ |
| Author(s) : Keller LJ , Nguyen TH , Liu LJ , Hurysz BM , Lakemeyer M , Guerra M , Gelsinger DJ , Chanin R , Ngo N , Lum KM , Faucher F , Ipock P , Niphakis MJ , Bhatt AS , O'Donoghue AJ , Huang KC , Bogyo M |
| Ref : Nat Chemical Biology , : , 2023 |
| Abstract : Keller_2023_Nat.Chem.Biol__ |
| ESTHER : Keller_2023_Nat.Chem.Biol__ |
| PubMedSearch : Keller_2023_Nat.Chem.Biol__ |
| PubMedID: 37349583 |
| Title : Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity - Brown_2022_Pathogens_11_1245 |
| Author(s) : Brown RWB , Sharma AI , Villanueva MR , Li X , Onguka O , Zilbermintz L , Nguyen H , Falk BA , Olson CL , Taylor JM , Epting CL , Kathayat RS , Amara N , Dickinson BC , Bogyo M , Engman DM |
| Ref : Pathogens , 11 : , 2022 |
| Abstract : Brown_2022_Pathogens_11_1245 |
| ESTHER : Brown_2022_Pathogens_11_1245 |
| PubMedSearch : Brown_2022_Pathogens_11_1245 |
| PubMedID: 36364996 |
| Gene_locus related to this paper: tryb2-q7yxi0 |
| Title : Identification of covalent inhibitors that disrupt M. tuberculosis growth by targeting multiple serine hydrolases involved in lipid metabolism - Babin_2022_Cell.Chem.Biol_29_897 |
| Author(s) : Babin BM , Keller LJ , Pinto Y , Li VL , Eneim AS , Vance SE , Terrell SM , Bhatt AS , Long JZ , Bogyo M |
| Ref : Cell Chemical Biology , 29 :897 , 2022 |
| Abstract : Babin_2022_Cell.Chem.Biol_29_897 |
| ESTHER : Babin_2022_Cell.Chem.Biol_29_897 |
| PubMedSearch : Babin_2022_Cell.Chem.Biol_29_897 |
| PubMedID: 34599874 |
| Title : Chemiluminescent Protease Probe for Rapid, Sensitive, and Inexpensive Detection of Live Mycobacterium tuberculosis - Babin_2021_ACS.Cent.Sci_7_803 |
| Author(s) : Babin BM , Fernandez-Cuervo G , Sheng J , Green O , Ordonez AA , Turner ML , Keller LJ , Jain SK , Shabat D , Bogyo M |
| Ref : ACS Cent Sci , 7 :803 , 2021 |
| Abstract : Babin_2021_ACS.Cent.Sci_7_803 |
| ESTHER : Babin_2021_ACS.Cent.Sci_7_803 |
| PubMedSearch : Babin_2021_ACS.Cent.Sci_7_803 |
| PubMedID: 34079897 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : Blocking Palmitoylation of Toxoplasma gondii Myosin Light Chain 1 Disrupts Glideosome Composition but Has Little Impact on Parasite Motility - Rompikuntal_2021_mSphere_6_ |
| Author(s) : Rompikuntal PK , Kent RS , Foe IT , Deng B , Bogyo M , Ward GE |
| Ref : mSphere , 6 : , 2021 |
| Abstract : Rompikuntal_2021_mSphere_6_ |
| ESTHER : Rompikuntal_2021_mSphere_6_ |
| PubMedSearch : Rompikuntal_2021_mSphere_6_ |
| PubMedID: 34011689 |
| Title : Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host - Onguka_2021_Cell.Chem.Biol__ |
| Author(s) : Onguka O , Babin BM , Lakemeyer M , Foe IT , Amara N , Terrell SM , Lum KM , Cieplak P , Niphakis MJ , Long JZ , Bogyo M |
| Ref : Cell Chemical Biology , : , 2021 |
| Abstract : Onguka_2021_Cell.Chem.Biol__ |
| ESTHER : Onguka_2021_Cell.Chem.Biol__ |
| PubMedSearch : Onguka_2021_Cell.Chem.Biol__ |
| PubMedID: 34043961 |
| Gene_locus related to this paper: toxgo-TgASH3 , toxgo-TgASH2 , toxgo-s4ug63 , toxgo-a0a125yz56 |
| Title : Strategies for Tuning the Selectivity of Chemical Probes that Target Serine Hydrolases - Faucher_2020_Cell.Chem.Biol_27_937 |
| Author(s) : Faucher F , Bennett JM , Bogyo M , Lovell S |
| Ref : Cell Chemical Biology , 27 :937 , 2020 |
| Abstract : Faucher_2020_Cell.Chem.Biol_27_937 |
| ESTHER : Faucher_2020_Cell.Chem.Biol_27_937 |
| PubMedSearch : Faucher_2020_Cell.Chem.Biol_27_937 |
| PubMedID: 32726586 |
| Title : Activity-based protein profiling in bacteria: Applications for identification of therapeutic targets and characterization of microbial communities - Keller_2020_Curr.Opin.Chem.Biol_54_45 |
| Author(s) : Keller LJ , Babin BM , Lakemeyer M , Bogyo M |
| Ref : Curr Opin Chemical Biology , 54 :45 , 2020 |
| Abstract : Keller_2020_Curr.Opin.Chem.Biol_54_45 |
| ESTHER : Keller_2020_Curr.Opin.Chem.Biol_54_45 |
| PubMedSearch : Keller_2020_Curr.Opin.Chem.Biol_54_45 |
| PubMedID: 31835131 |
| Title : Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus - Fellner_2020_ACS.Infect.Dis_6_2771 |
| Author(s) : Fellner M , Lentz CS , Jamieson SA , Brewster JL , Chen L , Bogyo M , Mace PD |
| Ref : ACS Infect Dis , 6 :2771 , 2020 |
| Abstract : Fellner_2020_ACS.Infect.Dis_6_2771 |
| ESTHER : Fellner_2020_ACS.Infect.Dis_6_2771 |
| PubMedSearch : Fellner_2020_ACS.Infect.Dis_6_2771 |
| PubMedID: 32865965 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |
| Title : The Antimalarial Natural Product Salinipostin A Identifies Essential alpha\/beta Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites - Yoo_2020_Cell.Chem.Biol_27_143 |
| Author(s) : Yoo E , Schulze CJ , Stokes BH , Onguka O , Yeo T , Mok S , Gnadig NF , Zhou Y , Kurita K , Foe IT , Terrell SM , Boucher MJ , Cieplak P , Kumpornsin K , Lee MCS , Linington RG , Long JZ , Uhlemann AC , Weerapana E , Fidock DA , Bogyo M |
| Ref : Cell Chemical Biology , 27 :143 , 2020 |
| Abstract : Yoo_2020_Cell.Chem.Biol_27_143 |
| ESTHER : Yoo_2020_Cell.Chem.Biol_27_143 |
| PubMedSearch : Yoo_2020_Cell.Chem.Biol_27_143 |
| PubMedID: 31978322 |
| Gene_locus related to this paper: plaf7-q8ii19 , plafa-a0a143zya4 , plaf7-q8iik5 , plafa-MAL8P1.38 , plafa-PF07.0040 , plafa-PF10.0020 , plafa-PF10.0379 , plafa-PF13.0153 |
| Title : Characterization of Serine Hydrolases Across Clinical Isolates of Commensal Skin Bacteria Staphylococcus epidermidis Using Activity-Based Protein Profiling - Keller_2020_ACS.Infect.Dis_6_930 |
| Author(s) : Keller LJ , Lentz CS , Chen YE , Metivier RJ , Weerapana E , Fischbach MA , Bogyo M |
| Ref : ACS Infect Dis , 6 :930 , 2020 |
| Abstract : Keller_2020_ACS.Infect.Dis_6_930 |
| ESTHER : Keller_2020_ACS.Infect.Dis_6_930 |
| PubMedSearch : Keller_2020_ACS.Infect.Dis_6_930 |
| PubMedID: 32298574 |
| Gene_locus related to this paper: staep-GEHD , staep-lipas , staep-SE0226 , staep-SE0245 , staep-SE0424 , staep-SE0564 , staep-SE0714 , staep-SE0980 , staep-SE1460 , staep-SE1780 , staep-SERP2035 , staep-SE2095 , staep-SE2213 , staep-SE2328 , staep-SE2403 |
| Title : A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision - Walker_2020_Cancer.Res_80_2045 |
| Author(s) : Walker E , Liu Y , Kim I , Biro M , Iyer SR , Ezaldein H , Scott J , Merati M , Mistur R , Zhou B , Straight B , Yim JJ , Bogyo M , Mann M , Wilson DL , Basilion JP , Popkin DL |
| Ref : Cancer Research , 80 :2045 , 2020 |
| Abstract : Walker_2020_Cancer.Res_80_2045 |
| ESTHER : Walker_2020_Cancer.Res_80_2045 |
| PubMedSearch : Walker_2020_Cancer.Res_80_2045 |
| PubMedID: 32132111 |
| Title : Synthetic Fluorogenic Peptides Reveal Dynamic Substrate Specificity of Depalmitoylases - Amara_2019_Cell.Chem.Biol_26_35 |
| Author(s) : Amara N , Foe IT , Onguka O , Garland M , Bogyo M |
| Ref : Cell Chemical Biology , 26 :35 , 2019 |
| Abstract : Amara_2019_Cell.Chem.Biol_26_35 |
| ESTHER : Amara_2019_Cell.Chem.Biol_26_35 |
| PubMedSearch : Amara_2019_Cell.Chem.Biol_26_35 |
| PubMedID: 30393067 |
| Title : Synthetic and biological approaches to map substrate specificities of proteases - Chen_2019_Biol.Chem_401_165 |
| Author(s) : Chen S , Yim JJ , Bogyo M |
| Ref : Biol Chem , 401 :165 , 2019 |
| Abstract : Chen_2019_Biol.Chem_401_165 |
| ESTHER : Chen_2019_Biol.Chem_401_165 |
| PubMedSearch : Chen_2019_Biol.Chem_401_165 |
| PubMedID: 31639098 |
| Title : Fluorescent Triazole Urea Activity-Based Probes for the Single-Cell Phenotypic Characterization of Staphylococcus aureus - Chen_2019_Angew.Chem.Int.Ed.Engl_58_5643 |
| Author(s) : Chen L , Keller LJ , Cordasco E , Bogyo M , Lentz CS |
| Ref : Angew Chem Int Ed Engl , 58 :5643 , 2019 |
| Abstract : Chen_2019_Angew.Chem.Int.Ed.Engl_58_5643 |
| ESTHER : Chen_2019_Angew.Chem.Int.Ed.Engl_58_5643 |
| PubMedSearch : Chen_2019_Angew.Chem.Int.Ed.Engl_58_5643 |
| PubMedID: 30768830 |
| Title : The Toxoplasma gondii Active Serine Hydrolase 4 Regulates Parasite Division and Intravacuolar Parasite Architecture - Foe_2018_mSphere_3_ |
| Author(s) : Foe IT , Onguka O , Amberg-Johnson K , Garner RM , Amara N , Beatty W , Yeh E , Bogyo M |
| Ref : mSphere , 3 : , 2018 |
| Abstract : Foe_2018_mSphere_3_ |
| ESTHER : Foe_2018_mSphere_3_ |
| PubMedSearch : Foe_2018_mSphere_3_ |
| PubMedID: 30232166 |
| Gene_locus related to this paper: toxgo-a0a125yz56 |
| Title : Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP) - Lentz_2018_Nat.Chem.Biol_14_609 |
| Author(s) : Lentz CS , Sheldon JR , Crawford LA , Cooper R , Garland M , Amieva MR , Weerapana E , Skaar EP , Bogyo M |
| Ref : Nat Chemical Biology , 14 :609 , 2018 |
| Abstract : Lentz_2018_Nat.Chem.Biol_14_609 |
| ESTHER : Lentz_2018_Nat.Chem.Biol_14_609 |
| PubMedSearch : Lentz_2018_Nat.Chem.Biol_14_609 |
| PubMedID: 29769740 |
| Gene_locus related to this paper: staau-MW2456 , staau-SA2422 |
| Title : Development of an activity-based probe for acyl-protein thioesterases - Garland_2018_PLoS.One_13_e0190255 |
| Author(s) : Garland M , Schulze CJ , Foe IT , van der Linden WA , Child MA , Bogyo M |
| Ref : PLoS ONE , 13 :e0190255 , 2018 |
| Abstract : Garland_2018_PLoS.One_13_e0190255 |
| ESTHER : Garland_2018_PLoS.One_13_e0190255 |
| PubMedSearch : Garland_2018_PLoS.One_13_e0190255 |
| PubMedID: 29364904 |
| Title : An in vivo multiplexed small-molecule screening platform - Gruner_2016_Nat.Methods_13_883 |
| Author(s) : Gruner BM , Schulze CJ , Yang D , Ogasawara D , Dix MM , Rogers ZN , Chuang CH , McFarland CD , Chiou SH , Brown JM , Cravatt BF , Bogyo M , Winslow MM |
| Ref : Nat Methods , 13 :883 , 2016 |
| Abstract : Gruner_2016_Nat.Methods_13_883 |
| ESTHER : Gruner_2016_Nat.Methods_13_883 |
| PubMedSearch : Gruner_2016_Nat.Methods_13_883 |
| PubMedID: 27617390 |
| Title : Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis - Lentz_2016_ACS.Infect.Dis_2_807 |
| Author(s) : Lentz CS , Ordonez AA , Kasperkiewicz P , La Greca F , O'Donoghue AJ , Schulze CJ , Powers JC , Craik CS , Drag M , Jain SK , Bogyo M |
| Ref : ACS Infect Dis , 2 :807 , 2016 |
| Abstract : Lentz_2016_ACS.Infect.Dis_2_807 |
| ESTHER : Lentz_2016_ACS.Infect.Dis_2_807 |
| PubMedSearch : Lentz_2016_ACS.Infect.Dis_2_807 |
| PubMedID: 27739665 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : Global Analysis of Palmitoylated Proteins in Toxoplasma gondii - Foe_2015_Cell.Host.Microbe_18_501 |
| Author(s) : Foe IT , Child MA , Majmudar JD , Krishnamurthy S , van der Linden WA , Ward GE , Martin BR , Bogyo M |
| Ref : Cell Host Microbe , 18 :501 , 2015 |
| Abstract : Foe_2015_Cell.Host.Microbe_18_501 |
| ESTHER : Foe_2015_Cell.Host.Microbe_18_501 |
| PubMedSearch : Foe_2015_Cell.Host.Microbe_18_501 |
| PubMedID: 26468752 |
| Title : Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion - Child_2013_Nat.Chem.Biol_9_651 |
| Author(s) : Child MA , Hall CI , Beck JR , Ofori LO , Albrow VE , Garland M , Bowyer PW , Bradley PJ , Powers JC , Boothroyd JC , Weerapana E , Bogyo M |
| Ref : Nat Chemical Biology , 9 :651 , 2013 |
| Abstract : Child_2013_Nat.Chem.Biol_9_651 |
| ESTHER : Child_2013_Nat.Chem.Biol_9_651 |
| PubMedSearch : Child_2013_Nat.Chem.Biol_9_651 |
| PubMedID: 23934245 |
| Gene_locus related to this paper: toxgo-s4ug63 |
| Title : Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum - Arastu-Kapur_2008_Nat.Chem.Biol_4_203 |
| Author(s) : Arastu-Kapur S , Ponder EL , Fonovic UP , Yeoh S , Yuan F , Fonovic M , Grainger M , Phillips CI , Powers JC , Bogyo M |
| Ref : Nat Chemical Biology , 4 :203 , 2008 |
| Abstract : Arastu-Kapur_2008_Nat.Chem.Biol_4_203 |
| ESTHER : Arastu-Kapur_2008_Nat.Chem.Biol_4_203 |
| PubMedSearch : Arastu-Kapur_2008_Nat.Chem.Biol_4_203 |
| PubMedID: 18246061 |