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| Title : Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity - Clader_2004_Bioorg.Med.Chem_12_319 |
| Author(s) : Clader JW , Billard W , Binch H, 3rd , Chen LY , Crosby G, Jr. , Duffy RA , Ford J , Kozlowski JA , Lachowicz JE , Li S , Liu C , McCombie SW , Vice S , Zhou G , Greenlee WJ |
| Ref : Bioorganic & Medicinal Chemistry , 12 :319 , 2004 |
| Abstract : Clader_2004_Bioorg.Med.Chem_12_319 |
| ESTHER : Clader_2004_Bioorg.Med.Chem_12_319 |
| PubMedSearch : Clader_2004_Bioorg.Med.Chem_12_319 |
| PubMedID: 14723952 |
| Title : Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists - Wang_2002_J.Med.Chem_45_5415 |
| Author(s) : Wang Y , Chackalamannil S , Hu Z , Greenlee WJ , Clader J , Boyle CD , Kaminski JJ , Billard W , Binch H, 3rd , Crosby G , Ruperto V , Duffy RA , Cohen-Williams M , Coffin VL , Cox KA , Grotz DE , Lachowicz JE |
| Ref : Journal of Medicinal Chemistry , 45 :5415 , 2002 |
| Abstract : Wang_2002_J.Med.Chem_45_5415 |
| ESTHER : Wang_2002_J.Med.Chem_45_5415 |
| PubMedSearch : Wang_2002_J.Med.Chem_45_5415 |
| PubMedID: 12459007 |
| Title : Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M(2) muscarinic receptor antagonists via benzamide modification - Boyle_2002_Bioorg.Med.Chem.Lett_12_3479 |
| Author(s) : Boyle CD , Vice SF , Campion J , Chackalamannil S , Lankin CM , McCombie SW , Billard W , Binch H, 3rd , Crosby G , Williams MC , Coffin VL , Cox KA , Grotz DE , Duffy RA , Ruperto V , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 12 :3479 , 2002 |
| Abstract : Boyle_2002_Bioorg.Med.Chem.Lett_12_3479 |
| ESTHER : Boyle_2002_Bioorg.Med.Chem.Lett_12_3479 |
| PubMedSearch : Boyle_2002_Bioorg.Med.Chem.Lett_12_3479 |
| PubMedID: 12419388 |
| Title : Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788 - Lachowicz_2001_Life.Sci_68(22-23)_2585 |
| Author(s) : Lachowicz JE , Duffy RA , Ruperto V , Kozlowski J , Zhou G , Clader J , Billard W , Binch H, 3rd , Crosby G , Cohen-Williams M , Strader CD , Coffin V |
| Ref : Life Sciences , 68 :2585 , 2001 |
| Abstract : Lachowicz_2001_Life.Sci_68(22-23)_2585 |
| ESTHER : Lachowicz_2001_Life.Sci_68(22-23)_2585 |
| PubMedSearch : Lachowicz_2001_Life.Sci_68(22-23)_2585 |
| PubMedID: 11392630 |
| Title : Benzylidene ketal derivatives as M2 muscarinic receptor antagonists - Boyle_2000_Bioorg.Med.Chem.Lett_10_2727 |
| Author(s) : Boyle CD , Chackalamannil S , Chen LY , Dugar S , Pushpavanam P , Billard W , Binch H, 3rd , Crosby G , Cohen-Williams M , Coffin VL , Duffy RA , Ruperto V , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 10 :2727 , 2000 |
| Abstract : Boyle_2000_Bioorg.Med.Chem.Lett_10_2727 |
| ESTHER : Boyle_2000_Bioorg.Med.Chem.Lett_10_2727 |
| PubMedSearch : Boyle_2000_Bioorg.Med.Chem.Lett_10_2727 |
| PubMedID: 11133078 |