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| Title : Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy - Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Bautista-Aguilera OM , Ismaili L , Chioua M , Andrys R , Schmidt M , Bzonek P , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Iriepa I , Refouvelet B , Musilek K , Marco-Contelles J |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| ESTHER : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| PubMedSearch : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 32486316 |
| Title : Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy - Zribi_2020_Molecules_25_ |
| Author(s) : Zribi L , Pachon-Angona I , Bautista-Aguilera OM , Diez-Iriepa D , Marco-Contelles J , Ismaili L , Iriepa I , Chabchoub F |
| Ref : Molecules , 25 : , 2020 |
| Abstract : Zribi_2020_Molecules_25_ |
| ESTHER : Zribi_2020_Molecules_25_ |
| PubMedSearch : Zribi_2020_Molecules_25_ |
| PubMedID: 32668671 |
| Title : Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile - Bautista-Aguilera_2018_J.Med.Chem_61_6937 |
| Author(s) : Bautista-Aguilera OM , Budni J , Mina F , Medeiros EB , Deuther-Conrad W , Entrena JM , Moraleda I , Iriepa I , Lopez-Munoz F , Marco-Contelles J |
| Ref : Journal of Medicinal Chemistry , 61 :6937 , 2018 |
| Abstract : Bautista-Aguilera_2018_J.Med.Chem_61_6937 |
| ESTHER : Bautista-Aguilera_2018_J.Med.Chem_61_6937 |
| PubMedSearch : Bautista-Aguilera_2018_J.Med.Chem_61_6937 |
| PubMedID: 29969030 |
| Title : Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases - Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| Author(s) : Bautista-Aguilera OM , Hagenow S , Palomino-Antolin A , Farre-Alins V , Ismaili L , Joffrin PL , Jimeno ML , Soukup O , Janockova J , Kalinowsky L , Proschak E , Iriepa I , Moraleda I , Schwed JS , Romero Martinez A , Lopez-Munoz F , Chioua M , Egea J , Ramsay RR , Marco-Contelles J , Stark H |
| Ref : Angew Chem Int Ed Engl , 56 :12765 , 2017 |
| Abstract : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| ESTHER : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| PubMedSearch : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| PubMedID: 28861918 |
| Title : Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy - Dgachi_2016_ChemMedChem_11_1318 |
| Author(s) : Dgachi Y , Ismaili L , Knez D , Benchekroun M , Martin H , Szalaj N , Wehle S , Bautista-Aguilera OM , Luzet V , Bonnet A , Malawska B , Gobec S , Chioua M , Decker M , Chabchoub F , Marco-Contelles J |
| Ref : ChemMedChem , 11 :1318 , 2016 |
| Abstract : Dgachi_2016_ChemMedChem_11_1318 |
| ESTHER : Dgachi_2016_ChemMedChem_11_1318 |
| PubMedSearch : Dgachi_2016_ChemMedChem_11_1318 |
| PubMedID: 26804623 |
| Title : The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators - Benchekroun_2016_J.Med.Chem_59_9967 |
| Author(s) : Benchekroun M , Romero A , Egea J , Leon R , Michalska P , Buendia I , Jimeno ML , Jun D , Janockova J , Sepsova V , Soukup O , Bautista-Aguilera OM , Refouvelet B , Ouari O , Marco-Contelles J , Ismaili L |
| Ref : Journal of Medicinal Chemistry , 59 :9967 , 2016 |
| Abstract : Benchekroun_2016_J.Med.Chem_59_9967 |
| ESTHER : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedSearch : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedID: 27736061 |
| Title : Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease - Dgachi_2016_Molecules_21_ |
| Author(s) : Dgachi Y , Bautista-Aguilera OM , Benchekroun M , Martin H , Bonet A , Knez D , Godyn J , Malawska B , Gobec S , Chioua M , Janockova J , Soukup O , Chabchoub F , Marco-Contelles J , Ismaili L |
| Ref : Molecules , 21 : , 2016 |
| Abstract : Dgachi_2016_Molecules_21_ |
| ESTHER : Dgachi_2016_Molecules_21_ |
| PubMedSearch : Dgachi_2016_Molecules_21_ |
| PubMedID: 27187348 |
| Title : Predicting targets of compounds against neurological diseases using cheminformatic methodology - Nikolic_2015_J.Comput.Aided.Mol.Des_29_183 |
| Author(s) : Nikolic K , Mavridis L , Bautista-Aguilera OM , Marco-Contelles J , Stark H , do Carmo Carreiras M , Rossi I , Massarelli P , Agbaba D , Ramsay RR , Mitchell JB |
| Ref : J Comput Aided Mol Des , 29 :183 , 2015 |
| Abstract : Nikolic_2015_J.Comput.Aided.Mol.Des_29_183 |
| ESTHER : Nikolic_2015_J.Comput.Aided.Mol.Des_29_183 |
| PubMedSearch : Nikolic_2015_J.Comput.Aided.Mol.Des_29_183 |
| PubMedID: 25425329 |
| Title : Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease - Wang_2014_Eur.J.Med.Chem_80_543 |
| Author(s) : Wang L , Esteban G , Ojima M , Bautista-Aguilera OM , Inokuchi T , Moraleda I , Iriepa I , Samadi A , Youdim MB , Romero A , Soriano E , Herrero R , Fernandez Fernandez AP , Ricardo Martinez M , Marco-Contelles J , Unzeta M |
| Ref : Eur Journal of Medicinal Chemistry , 80 :543 , 2014 |
| Abstract : Wang_2014_Eur.J.Med.Chem_80_543 |
| ESTHER : Wang_2014_Eur.J.Med.Chem_80_543 |
| PubMedSearch : Wang_2014_Eur.J.Med.Chem_80_543 |
| PubMedID: 24813882 |
| Title : Multipotent cholinesterase\/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids - Bautista-Aguilera_2014_Drug.Des.Devel.Ther_8_1893 |
| Author(s) : Bautista-Aguilera OM , Esteban G , Chioua M , Nikolic K , Agbaba D , Moraleda I , Iriepa I , Soriano E , Samadi A , Unzeta M , Marco-Contelles J |
| Ref : Drug Des Devel Ther , 8 :1893 , 2014 |
| Abstract : Bautista-Aguilera_2014_Drug.Des.Devel.Ther_8_1893 |
| ESTHER : Bautista-Aguilera_2014_Drug.Des.Devel.Ther_8_1893 |
| PubMedSearch : Bautista-Aguilera_2014_Drug.Des.Devel.Ther_8_1893 |
| PubMedID: 25378907 |
| Title : Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase\/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease - Bautista-Aguilera_2014_Eur.J.Med.Chem_75C_82 |
| Author(s) : Bautista-Aguilera OM , Esteban G , Bolea I , Nikolic K , Agbaba D , Moraleda I , Iriepa I , Samadi A , Soriano E , Unzeta M , Marco-Contelles J |
| Ref : Eur Journal of Medicinal Chemistry , 75C :82 , 2014 |
| Abstract : Bautista-Aguilera_2014_Eur.J.Med.Chem_75C_82 |
| ESTHER : Bautista-Aguilera_2014_Eur.J.Med.Chem_75C_82 |
| PubMedSearch : Bautista-Aguilera_2014_Eur.J.Med.Chem_75C_82 |
| PubMedID: 24530494 |
| Title : N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2- yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor - Bautista-Aguilera_2014_J.Med.Chem_57_10455 |
| Author(s) : Bautista-Aguilera OM , Samadi A , Chioua M , Nikolic K , Filipic S , Agbaba D , Soriano E , de Andres L , Rodriguez-Franco MI , Alcaro S , Ramsay RR , Ortuso F , Yanez M , Marco-Contelles J |
| Ref : Journal of Medicinal Chemistry , 57 :10455 , 2014 |
| Abstract : Bautista-Aguilera_2014_J.Med.Chem_57_10455 |
| ESTHER : Bautista-Aguilera_2014_J.Med.Chem_57_10455 |
| PubMedSearch : Bautista-Aguilera_2014_J.Med.Chem_57_10455 |
| PubMedID: 25418133 |