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| Title : BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS - Prchalova_2023_Biomed.Pharmacother_167_115490 |
| Author(s) : Prchalova E , Sukupova M , Malinak D , Andrys R , Sivak L , Pekarik V , Skarka A , Svobodova J , Prchal L , Fresser L , Heger Z , Musilek K |
| Ref : Biomed Pharmacother , 167 :115490 , 2023 |
| Abstract : Prchalova_2023_Biomed.Pharmacother_167_115490 |
| ESTHER : Prchalova_2023_Biomed.Pharmacother_167_115490 |
| PubMedSearch : Prchalova_2023_Biomed.Pharmacother_167_115490 |
| PubMedID: 37722189 |
| Title : Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease - Svobodova_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Svobodova B , Pulkrabkova L , Panek D , Misiachna A , Kolcheva M , Andrys R , Handl J , Capek J , Nyvltova P , Rousar T , Prchal L , Hepnarova V , Hrabinova M , Muckova L , Tosnerova D , Karabanovich G , Finger V , Soukup O , Horak M , Korabecny J |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : Svobodova_2023_Int.J.Mol.Sci_24_ |
| ESTHER : Svobodova_2023_Int.J.Mol.Sci_24_ |
| PubMedSearch : Svobodova_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37298087 |
| Title : Direct Chiral Supercritical Fluid Chromatography-Mass Spectrometry Analysis of Monoacylglycerol and Diacylglycerol Isomers for the Study of Lipase-Catalyzed Hydrolysis of Triacylglycerols - Kozlov_2023_Anal.Chem__ |
| Author(s) : Kozlov O , Horakova E , Rademacherova S , Malinak D , Andrys R , Prchalova E , Lisa M |
| Ref : Analytical Chemistry , : , 2023 |
| Abstract : Kozlov_2023_Anal.Chem__ |
| ESTHER : Kozlov_2023_Anal.Chem__ |
| PubMedSearch : Kozlov_2023_Anal.Chem__ |
| PubMedID: 36893116 |
| Title : Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents - Zorbaz_2022_Eur.J.Med.Chem_238_114377 |
| Author(s) : Zorbaz T , Malinak D , Hofmanova T , Marakovic N , Zunec S , Hrvat NM , Andrys R , Psotka M , Zandona A , Svobodova J , Prchal L , Fingler S , Katalinic M , Kovarik Z , Musilek K |
| Ref : Eur Journal of Medicinal Chemistry , 238 :114377 , 2022 |
| Abstract : Zorbaz_2022_Eur.J.Med.Chem_238_114377 |
| ESTHER : Zorbaz_2022_Eur.J.Med.Chem_238_114377 |
| PubMedSearch : Zorbaz_2022_Eur.J.Med.Chem_238_114377 |
| PubMedID: 35526478 |
| Title : Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities - Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| Author(s) : Chrienova Z , Nepovimova E , Andrys R , Dolezal R , Janockova J , Muckova L , Fabova L , Soukup O , Oleksak P , Valis M , Korabecny J , Marco-Contelles J , Kuca K |
| Ref : J Enzyme Inhib Med Chem , 37 :2605 , 2022 |
| Abstract : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| ESTHER : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| PubMedSearch : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| PubMedID: 36131624 |
| Title : Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870 - Karasova_2022_Food.Chem.Toxicol__113236 |
| Author(s) : Karasova JZ , Kassa J , Hepnarova V , Pejchal J , Junova L , Andrys R , Malinak D , Bzonek P , Kohoutova Z , Musilek K |
| Ref : Food & Chemical Toxicology , :113236 , 2022 |
| Abstract : Karasova_2022_Food.Chem.Toxicol__113236 |
| ESTHER : Karasova_2022_Food.Chem.Toxicol__113236 |
| PubMedSearch : Karasova_2022_Food.Chem.Toxicol__113236 |
| PubMedID: 35738326 |
| Title : Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides - Kohoutova_2022_J.Enzyme.Inhib.Med.Chem_37_760 |
| Author(s) : Kohoutova Z , Malinak D , Andrys R , Svobodova J , Psotka M , Schmidt M , Prchal L , Musilek K |
| Ref : J Enzyme Inhib Med Chem , 37 :760 , 2022 |
| Abstract : Kohoutova_2022_J.Enzyme.Inhib.Med.Chem_37_760 |
| ESTHER : Kohoutova_2022_J.Enzyme.Inhib.Med.Chem_37_760 |
| PubMedSearch : Kohoutova_2022_J.Enzyme.Inhib.Med.Chem_37_760 |
| PubMedID: 35193448 |
| Title : Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening - Handl_2021_Chem.Res.Toxicol__ |
| Author(s) : Handl J , Malinak D , Capek J , Andrys R , Rousarova E , Hauschke M , Bruckova L , Cesla P , Rousar T , Musilek K |
| Ref : Chemical Research in Toxicology , : , 2021 |
| Abstract : Handl_2021_Chem.Res.Toxicol__ |
| ESTHER : Handl_2021_Chem.Res.Toxicol__ |
| PubMedSearch : Handl_2021_Chem.Res.Toxicol__ |
| PubMedID: 33566584 |
| Title : Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies - Al Mamun_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Al Mamun A , Pidany F , Hulcova D , Marikova J , Kucera T , Schmidt M , Catapano MC , Hrabinova M , Jun D , Muckova L , Kunes J , Janousek J , Andrys R , Novakova L , Perinova R , Maafi N , Soukup O , Korabecny J , Cahlikova L |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : Al Mamun_2021_Int.J.Mol.Sci_22_ |
| ESTHER : Al Mamun_2021_Int.J.Mol.Sci_22_ |
| PubMedSearch : Al Mamun_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 34361074 |
| Title : Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry - Andrys_2021_Mol.Pharm__ |
| Author(s) : Andrys R , Klusonova A , Lisa M , Kassa J , Karasova JZ |
| Ref : Mol Pharm , : , 2021 |
| Abstract : Andrys_2021_Mol.Pharm__ |
| ESTHER : Andrys_2021_Mol.Pharm__ |
| PubMedSearch : Andrys_2021_Mol.Pharm__ |
| PubMedID: 34019427 |
| Title : Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates - Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| Author(s) : Lee HM , Andrys R , Jonczyk J , Kim K , Vishakantegowda AG , Malinak D , Skarka A , Schmidt M , Vaskova M , Latka K , Bajda M , Jung YS , Malawska B , Musilek K |
| Ref : J Enzyme Inhib Med Chem , 36 :437 , 2021 |
| Abstract : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| ESTHER : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| PubMedSearch : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| PubMedID: 33467931 |
| Title : (+\/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease - Ismaili_2021_ACS.Chem.Neurosci__ |
| Author(s) : Ismaili L , Monnin J , Etievant A , Arribas RL , Viejo L , Refouvelet B , Soukup O , Janockova J , Hepnarova V , Korabecny J , Kucera T , Jun D , Andrys R , Musilek K , Baguet A , Garcia-Frutos EM , De Simone A , Andrisano V , Bartolini M , de los Rios C , Marco-Contelles J , Haffen E |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : Ismaili_2021_ACS.Chem.Neurosci__ |
| ESTHER : Ismaili_2021_ACS.Chem.Neurosci__ |
| PubMedSearch : Ismaili_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33797877 |
| Title : Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors - Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| Author(s) : Gorecki L , Andrys R , Schmidt M , Kucera T , Psotka M , Svobodova B , Hrabcova V , Hepnarova V , Bzonek P , Jun D , Kuca K , Korabecny J , Musilek K |
| Ref : ACS Med Chem Lett , 11 :65 , 2020 |
| Abstract : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| ESTHER : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| PubMedSearch : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| PubMedID: 31938465 |
| Title : Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy - Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Bautista-Aguilera OM , Ismaili L , Chioua M , Andrys R , Schmidt M , Bzonek P , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Iriepa I , Refouvelet B , Musilek K , Marco-Contelles J |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| ESTHER : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| PubMedSearch : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 32486316 |
| Title : Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators - Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| Author(s) : Malinak D , Dolezal R , Hepnarova V , Hozova M , Andrys R , Bzonek P , Racakova V , Korabecny J , Gorecki L , Mezeiova E , Psotka M , Jun D , Kuca K , Musilek K |
| Ref : J Enzyme Inhib Med Chem , 35 :478 , 2020 |
| Abstract : Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| ESTHER : Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| PubMedSearch : Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| PubMedID: 31910701 |
| Title : Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness - Karasova_2020_Toxicol.Lett_320_64 |
| Author(s) : Karasova JZ , Hepnarova V , Andrys R , Lisa M , Jost P , Muckova L , Pejchal J , Herman D , Jun D , Kassa J , Kuca K |
| Ref : Toxicol Lett , 320 :64 , 2020 |
| Abstract : Karasova_2020_Toxicol.Lett_320_64 |
| ESTHER : Karasova_2020_Toxicol.Lett_320_64 |
| PubMedSearch : Karasova_2020_Toxicol.Lett_320_64 |
| PubMedID: 31794810 |
| Title : 1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy - Kapron_2020_J.Enzyme.Inhib.Med.Chem_35_993 |
| Author(s) : Kapron B , Czarnomysy R , Wysokinski M , Andrys R , Musilek K , Angeli A , Supuran CT , Plech T |
| Ref : J Enzyme Inhib Med Chem , 35 :993 , 2020 |
| Abstract : Kapron_2020_J.Enzyme.Inhib.Med.Chem_35_993 |
| ESTHER : Kapron_2020_J.Enzyme.Inhib.Med.Chem_35_993 |
| PubMedSearch : Kapron_2020_J.Enzyme.Inhib.Med.Chem_35_993 |
| PubMedID: 32253957 |
| Title : Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer's Disease Therapy - Malek_2019_Curr.Alzheimer.Res_16_815 |
| Author(s) : Malek R , Refouvelet B , Benchekroun M , Iriepa I , Moraleda I , Andrys R , Musilek K , Marco-Contelles J , Ismaili L |
| Ref : Curr Alzheimer Res , 16 :815 , 2019 |
| Abstract : Malek_2019_Curr.Alzheimer.Res_16_815 |
| ESTHER : Malek_2019_Curr.Alzheimer.Res_16_815 |
| PubMedSearch : Malek_2019_Curr.Alzheimer.Res_16_815 |
| PubMedID: 31660831 |
| Title : Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy - Pachon-Angona_2019_J.Enzyme.Inhib.Med.Chem_34_479 |
| Author(s) : Pachon-Angona I , Refouvelet B , Andrys R , Martin H , Luzet V , Iriepa I , Moraleda I , Diez-Iriepa D , Oset-Gasque MJ , Marco-Contelles J , Musilek K , Ismaili L |
| Ref : J Enzyme Inhib Med Chem , 34 :479 , 2019 |
| Abstract : Pachon-Angona_2019_J.Enzyme.Inhib.Med.Chem_34_479 |
| ESTHER : Pachon-Angona_2019_J.Enzyme.Inhib.Med.Chem_34_479 |
| PubMedSearch : Pachon-Angona_2019_J.Enzyme.Inhib.Med.Chem_34_479 |
| PubMedID: 30712420 |
| Title : Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents - Zorbaz_2018_J.Med.Chem_61_10753 |
| Author(s) : Zorbaz T , Malinak D , Marakovic N , Macek Hrvat N , Zandona A , Novotny M , Skarka A , Andrys R , Benkova M , Soukup O , Katalinic M , Kuca K , Kovarik Z , Musilek K |
| Ref : Journal of Medicinal Chemistry , 61 :10753 , 2018 |
| Abstract : Zorbaz_2018_J.Med.Chem_61_10753 |
| ESTHER : Zorbaz_2018_J.Med.Chem_61_10753 |
| PubMedSearch : Zorbaz_2018_J.Med.Chem_61_10753 |
| PubMedID: 30383374 |