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| Title : SAR of alpha7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore - Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633 |
| Author(s) : Schrimpf MR , Sippy KB , Briggs CA , Anderson DJ , Li T , Ji J , Frost JM , Surowy CS , Bunnelle WH , Gopalakrishnan M , Meyer MD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1633 , 2012 |
| Abstract : Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633 |
| ESTHER : Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633 |
| PubMedSearch : Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633 |
| PubMedID: 22281189 |
| Title : Role of alpha7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-alpha (TNF-alpha) as revealed by subtype selective agonists - Li_2011_J.Neuroimmunol_239_37 |
| Author(s) : Li J , Mathieu SL , Harris R , Ji J , Anderson DJ , Malysz J , Bunnelle WH , Waring JF , Marsh KC , Murtaza A , Olson LM , Gopalakrishnan M |
| Ref : Journal of Neuroimmunology , 239 :37 , 2011 |
| Abstract : Li_2011_J.Neuroimmunol_239_37 |
| ESTHER : Li_2011_J.Neuroimmunol_239_37 |
| PubMedSearch : Li_2011_J.Neuroimmunol_239_37 |
| PubMedID: 21911260 |
| Title : Poster: In vitro pharmacological characterization of ABT-779, a novel positive allosteric modulator of alpha7 nAChRs - |
| Author(s) : Malysz J , Gronlien JH , Briggs CA , Anderson DJ , El-Kouhen R , Drescher K , Ween H , Thorin-Hagene K , Mortell K , Lee C-H , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 82 :1030 , 2011 |
| PubMedID: |
| Title : Functional characterization and high-throughput screening of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors in IMR-32 neuroblastoma cells - Gopalakrishnan_2011_Assay.Drug.Dev.Technol_9_635 |
| Author(s) : Gopalakrishnan SM , Philip BM , Gronlien JH , Malysz J , Anderson DJ , Gopalakrishnan M , Warrior U , Burns DJ |
| Ref : Assay Drug Dev Technol , 9 :635 , 2011 |
| Abstract : Gopalakrishnan_2011_Assay.Drug.Dev.Technol_9_635 |
| ESTHER : Gopalakrishnan_2011_Assay.Drug.Dev.Technol_9_635 |
| PubMedSearch : Gopalakrishnan_2011_Assay.Drug.Dev.Technol_9_635 |
| PubMedID: 21309712 |
| Title : Structure-activity studies of diazabicyclo[3.3.0]octane-substituted pyrazines and pyridines as potent alpha4beta2 nicotinic acetylcholine receptor ligands - Scanio_2011_J.Med.Chem_54_7678 |
| Author(s) : Scanio MJ , Shi L , Bunnelle WH , Anderson DJ , Helfrich RJ , Malysz J , Thorin-Hagene KK , Van Handel CE , Marsh KC , Lee CH , Gopalakrishnan M |
| Ref : Journal of Medicinal Chemistry , 54 :7678 , 2011 |
| Abstract : Scanio_2011_J.Med.Chem_54_7678 |
| ESTHER : Scanio_2011_J.Med.Chem_54_7678 |
| PubMedSearch : Scanio_2011_J.Med.Chem_54_7678 |
| PubMedID: 21962147 |
| Title : In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease - Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| Author(s) : Bitner RS , Bunnelle WH , Decker MW , Drescher KU , Kohlhaas KL , Markosyan S , Marsh KC , Nikkel AL , Browman K , Radek R , Anderson DJ , Buccafusco JJ , Gopalakrishnan M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :875 , 2010 |
| Abstract : Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| ESTHER : Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| PubMedSearch : Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| PubMedID: 20504913 |
| Title : Syntheses and structure-activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel alpha7 neuronal nicotinic receptor (NNR) ligands - Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| Author(s) : Li T , Bunnelle WH , Ryther KB , Anderson DJ , Malysz J , Helfrich R , Gronlien JH , Hakerud M , Peters D , Schrimpf MR , Gopalakrishnan M , Ji J |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :3636 , 2010 |
| Abstract : Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| ESTHER : Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| PubMedSearch : Li_2010_Bioorg.Med.Chem.Lett_20_3636 |
| PubMedID: 20472430 |
| Title : Structure-activity relationships of N-substituted ligands for the alpha7 nicotinic acetylcholine receptor - Mortell_2010_Bioorg.Med.Chem.Lett_20_104 |
| Author(s) : Mortell KH , Schrimpf MR , Bunnelle WH , Anderson DJ , Gronlien JH , Hagene KT , Gopalakrishnan M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :104 , 2010 |
| Abstract : Mortell_2010_Bioorg.Med.Chem.Lett_20_104 |
| ESTHER : Mortell_2010_Bioorg.Med.Chem.Lett_20_104 |
| PubMedSearch : Mortell_2010_Bioorg.Med.Chem.Lett_20_104 |
| PubMedID: 19954975 |
| Title : In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107 - Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| Author(s) : Malysz J , Anderson DJ , Gronlien JH , Ji J , Bunnelle WH , Hakerud M , Thorin-Hagene K , Ween H , Helfrich R , Hu M , Gubbins E , Gopalakrishnan S , Puttfarcken PS , Briggs CA , Li J , Meyer MD , Dyhring T , Ahring PK , Nielsen EO , Peters D , Timmermann DB , Gopalakrishnan M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :863 , 2010 |
| Abstract : Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| ESTHER : Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| PubMedSearch : Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| PubMedID: 20504915 |
| Title : Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha4beta2 subunit combination - Anderson_2009_Biochem.Pharmacol_78(7)_844 |
| Author(s) : Anderson DJ , Malysz J , Gronlien JH , El Kouhen R , Hakerud M , Wetterstrand C , Briggs CA , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 78 :844 , 2009 |
| Abstract : Anderson_2009_Biochem.Pharmacol_78(7)_844 |
| ESTHER : Anderson_2009_Biochem.Pharmacol_78(7)_844 |
| PubMedSearch : Anderson_2009_Biochem.Pharmacol_78(7)_844 |
| PubMedID: 19555668 |
| Title : Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors - Briggs_2009_Br.J.Pharmacol_158_1486 |
| Author(s) : Briggs CA , Gronlien JH , Curzon P , Timmermann DB , Ween H , Thorin-Hagene K , Kerr P , Anderson DJ , Malysz J , Dyhring T , Olsen GM , Peters D , Bunnelle WH , Gopalakrishnan M |
| Ref : British Journal of Pharmacology , 158 :1486 , 2009 |
| Abstract : Briggs_2009_Br.J.Pharmacol_158_1486 |
| ESTHER : Briggs_2009_Br.J.Pharmacol_158_1486 |
| PubMedSearch : Briggs_2009_Br.J.Pharmacol_158_1486 |
| PubMedID: 19845675 |
| Title : In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile - Malysz_2009_J.Pharmacol.Exp.Ther_330_257 |
| Author(s) : Malysz J , Gronlien JH , Anderson DJ , Hakerud M , Thorin-Hagene K , Ween H , Wetterstrand C , Briggs CA , Faghih R , Bunnelle WH , Gopalakrishnan M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :257 , 2009 |
| Abstract : Malysz_2009_J.Pharmacol.Exp.Ther_330_257 |
| ESTHER : Malysz_2009_J.Pharmacol.Exp.Ther_330_257 |
| PubMedSearch : Malysz_2009_J.Pharmacol.Exp.Ther_330_257 |
| PubMedID: 19389923 |
| Title : Poster: Radioligand binding characterization of [3H]-A-998679: A novel positive allosteric modulator of alpha4\/beta2 nAChRs - |
| Author(s) : Anderson DJ , Vaidyanathan S , Namovic M , Donnelly-Roberts D , Lee L , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 78 :903 , 2009 |
| PubMedID: |
| Title : Poster: Profile of A-716096, a novel thiazolylidine positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor - |
| Author(s) : Donnelly-Roberts D , Malysz J , Faghih R , Gronlien H , Haakerud M , Thorin-Hagne K , Ween H , Gopalakrishnan SM , Hu M , Li J , Anderson DJ , Kohlhaas KL , Namovic M , Radek R , Robb H , Briggs CA , Bitner RS , Bunnelle WH , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 78 :912 , 2009 |
| PubMedID: |
| Title : Pharmacology of alpha7 nicotinic acetylcholine receptor mediated extracellular signal-regulated kinase signalling in PC12 cells - El Kouhen_2009_Br.J.Pharmacol_156_638 |
| Author(s) : El Kouhen R , Hu M , Anderson DJ , Li J , Gopalakrishnan M |
| Ref : British Journal of Pharmacology , 156 :638 , 2009 |
| Abstract : El Kouhen_2009_Br.J.Pharmacol_156_638 |
| ESTHER : El Kouhen_2009_Br.J.Pharmacol_156_638 |
| PubMedSearch : El Kouhen_2009_Br.J.Pharmacol_156_638 |
| PubMedID: 19226255 |
| Title : Poster: Role of alpha-7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-alpha (TNF-alpha) as Revealed by subtype selective agonists - |
| Author(s) : Li J , Mathieu SL , Harris R , Ji J , Anderson DJ , Malysz J , Bunnelle WH , Waring JF , Marsh KC , Murtaza A , Olson LM , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 78 :924 , 2009 |
| PubMedID: |
| Title : Poster: In vitro pharmacological profile of a novel alpha4\/beta2 positive allosteric modulator NS9283 (A-969933) - |
| Author(s) : Malysz J , Dyhring T , Ahring PK , Olsen GM , Peters D , Gronlien JH , Wetterstrand C , Ween H , Haakerud M , Thorin-Hagene K , Andersen E , Anderson DJ , Hu M , Kroeger PE , Lee CHL , Gopalakrishnan M , Timmermann DB |
| Ref : Biochemical Pharmacology , 78 :919 , 2009 |
| PubMedID: |
| Title : [3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]hept ane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain - Anderson_2008_J.Pharmacol.Exp.Ther_324_179 |
| Author(s) : Anderson DJ , Bunnelle W , Surber B , Du J , Surowy C , Tribollet E , Marguerat A , Bertrand D , Gopalakrishnan M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 324 :179 , 2008 |
| Abstract : Anderson_2008_J.Pharmacol.Exp.Ther_324_179 |
| ESTHER : Anderson_2008_J.Pharmacol.Exp.Ther_324_179 |
| PubMedSearch : Anderson_2008_J.Pharmacol.Exp.Ther_324_179 |
| PubMedID: 17959745 |
| Title : Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties - Tietje_2008_CNS.Neurosci.Ther_14_65 |
| Author(s) : Tietje KR , Anderson DJ , Bitner RS , Blomme EA , Brackemeyer PJ , Briggs CA , Browman KE , Bury D , Curzon P , Drescher KU , Frost JM , Fryer RM , Fox GB , Gronlien JH , Hakerud M , Gubbins EJ , Halm S , Harris R , Helfrich RJ , Kohlhaas KL , Law D , Malysz J , Marsh KC , Martin RL , Meyer MD , Molesky AL , Nikkel AL , Otte S , Pan L , Puttfarcken PS , Radek RJ , Robb HM , Spies E , Thorin-Hagene K , Waring JF , Ween H , Xu H , Gopalakrishnan M , Bunnelle WH |
| Ref : CNS Neurosci Ther , 14 :65 , 2008 |
| Abstract : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| ESTHER : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedSearch : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedID: 18482100 |
| Title : Analysis of gene expression profiles in rat hippocampus following treatment with nicotine and an alpha7 nAChR selective agonist - Waring_2008_Neurosci.Res_60_266 |
| Author(s) : Waring JF , Abel S , Li J , Bitner RS , Nikkel AL , Blomme EA , Anderson DJ , Gopalakrishnan M |
| Ref : Neurosci Res , 60 :266 , 2008 |
| Abstract : Waring_2008_Neurosci.Res_60_266 |
| ESTHER : Waring_2008_Neurosci.Res_60_266 |
| PubMedSearch : Waring_2008_Neurosci.Res_60_266 |
| PubMedID: 18164502 |
| Title : alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues - Briggs_2008_Br.J.Pharmacol_153_1054 |
| Author(s) : Briggs CA , Schrimpf MR , Anderson DJ , Gubbins EJ , Gronlien JH , Hakerud M , Ween H , Thorin-Hagene K , Malysz J , Li J , Bunnelle WH , Gopalakrishnan M , Meyer MD |
| Ref : British Journal of Pharmacology , 153 :1054 , 2008 |
| Abstract : Briggs_2008_Br.J.Pharmacol_153_1054 |
| ESTHER : Briggs_2008_Br.J.Pharmacol_153_1054 |
| PubMedSearch : Briggs_2008_Br.J.Pharmacol_153_1054 |
| PubMedID: 18157163 |
| Title : A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models - Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| Author(s) : Ji J , Bunnelle WH , Anderson DJ , Faltynek C , Dyhring T , Ahring PK , Rueter LE , Curzon P , Buckley MJ , Marsh KC , Kempf-Grote A , Meyer MD |
| Ref : Biochemical Pharmacology , 74 :1253 , 2007 |
| Abstract : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| ESTHER : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| PubMedSearch : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| PubMedID: 17854775 |
| Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578 |
| Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M |
| Ref : Journal of Neuroscience , 27 :10578 , 2007 |
| Abstract : Bitner_2007_J.Neurosci_27_10578 |
| ESTHER : Bitner_2007_J.Neurosci_27_10578 |
| PubMedSearch : Bitner_2007_J.Neurosci_27_10578 |
| PubMedID: 17898229 |
| Title : Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment - Curzon_2006_Neurosci.Lett_410_15 |
| Author(s) : Curzon P , Anderson DJ , Nikkel AL , Fox GB , Gopalakrishnan M , Decker MW , Bitner RS |
| Ref : Neuroscience Letters , 410 :15 , 2006 |
| Abstract : Curzon_2006_Neurosci.Lett_410_15 |
| ESTHER : Curzon_2006_Neurosci.Lett_410_15 |
| PubMedSearch : Curzon_2006_Neurosci.Lett_410_15 |
| PubMedID: 17055644 |
| Title : A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor - Rueter_2006_CNS.Drug.Rev_12_100 |
| Author(s) : Rueter LE , Donnelly-Roberts D , Curzon P , Briggs CA , Anderson DJ , Bitner RS |
| Ref : CNS Drug Rev , 12 :100 , 2006 |
| Abstract : Rueter_2006_CNS.Drug.Rev_12_100 |
| ESTHER : Rueter_2006_CNS.Drug.Rev_12_100 |
| PubMedSearch : Rueter_2006_CNS.Drug.Rev_12_100 |
| PubMedID: 16958984 |
| Title : ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders - Rueter_2004_CNS.Drug.Rev_10_167 |
| Author(s) : Rueter LE , Anderson DJ , Briggs CA , Donnelly-Roberts D , Gintant GA , Gopalakrishnan M , Lin NH , Osinski MA , Reinhart GA , Buckley MJ , Martin RL , McDermott JS , Preusser LC , Seifert TR , Su Z , Cox BF , Decker MW , Sullivan JP |
| Ref : CNS Drug Rev , 10 :167 , 2004 |
| Abstract : Rueter_2004_CNS.Drug.Rev_10_167 |
| ESTHER : Rueter_2004_CNS.Drug.Rev_10_167 |
| PubMedSearch : Rueter_2004_CNS.Drug.Rev_10_167 |
| PubMedID: 15179445 |
| Title : The identification of novel structural compound classes exhibiting high affinity for neuronal nicotinic acetylcholine receptors and analgesic efficacy in preclinical models of pain - Meyer_2000_Eur.J.Pharmacol_393_171 |
| Author(s) : Meyer MD , Decker MW , Rueter LE , Anderson DJ , Dart MJ , Kim KH , Sullivan JP , Williams M |
| Ref : European Journal of Pharmacology , 393 :171 , 2000 |
| Abstract : Meyer_2000_Eur.J.Pharmacol_393_171 |
| ESTHER : Meyer_2000_Eur.J.Pharmacol_393_171 |
| PubMedSearch : Meyer_2000_Eur.J.Pharmacol_393_171 |
| PubMedID: 10771011 |
| Title : Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors - Holladay_1998_J.Med.Chem_41_407 |
| Author(s) : Holladay MW , Wasicak JT , Lin NH , He Y , Ryther KB , Bannon AW , Buckley MJ , Kim DJ , Decker MW , Anderson DJ , Campbell JE , Kuntzweiler TA , Donnelly-Roberts D , Piattoni-Kaplan M , Briggs CA , Williams M , Arneric SP |
| Ref : Journal of Medicinal Chemistry , 41 :407 , 1998 |
| Abstract : Holladay_1998_J.Med.Chem_41_407 |
| ESTHER : Holladay_1998_J.Med.Chem_41_407 |
| PubMedSearch : Holladay_1998_J.Med.Chem_41_407 |
| PubMedID: 9484491 |
| Title : Synthesis and structure-activity relationships of pyridine-modified analogs of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543, a potent nicotinic acetylcholine receptor agonist - Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| Author(s) : Lin NH , Gunn DE , Li Y , He Y , Bai H , Ryther KB , Kuntzweiler T , Donnelly-Roberts D , Anderson DJ , Campbell JE , Sullivan JP , Arneric SP , Holladay MW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :249 , 1998 |
| Abstract : Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| ESTHER : Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| PubMedSearch : Lin_1998_Bioorg.Med.Chem.Lett_8_249 |
| PubMedID: 9871663 |
| Title : ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization - Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
| Author(s) : Donnelly-Roberts D , Puttfarcken PS , Kuntzweiler TA , Briggs CA , Anderson DJ , Campbell JE , Piattoni-Kaplan M , McKenna DG , Wasicak JT , Holladay MW , Williams M , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 285 :777 , 1998 |
| Abstract : Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
| ESTHER : Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
| PubMedSearch : Donnelly-Roberts_1998_J.Pharmacol.Exp.Ther_285_777 |
| PubMedID: 9580626 |
| Title : Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice - Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| Author(s) : Holladay MW , Bai H , Li Y , Lin NH , Daanen JF , Ryther KB , Wasicak JT , Kincaid JF , He Y , Hettinger AM , Huang P , Anderson DJ , Bannon AW , Buckley MJ , Campbell JE , Donnelly-Roberts D , Gunther KL , Kim DJ , Kuntzweiler TA , Sullivan JP , Decker MW , Arneric SP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :2797 , 1998 |
| Abstract : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| ESTHER : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| PubMedSearch : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797 |
| PubMedID: 9873625 |
| Title : ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties - Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| Author(s) : Sullivan JP , Donnelly-Roberts D , Briggs CA , Anderson DJ , Gopalakrishnan M , Xue IC , Piattoni-Kaplan M , Molinari E , Campbell JE , McKenna DG , Gunn DE , Lin NH , Ryther KB , He Y , Holladay MW , Wonnacott S , Williams M , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :235 , 1997 |
| Abstract : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| ESTHER : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| PubMedSearch : Sullivan_1997_J.Pharmacol.Exp.Ther_283_235 |
| PubMedID: 9336329 |
| Title : Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo - Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| Author(s) : Briggs CA , Anderson DJ , Brioni JD , Buccafusco JJ , Buckley MJ , Campbell JE , Decker MW , Donnelly-Roberts D , Elliott RL , Gopalakrishnan M , Holladay MW , Hui YH , Jackson WJ , Kim DJ , Marsh KC , O'Neill A , Prendergast MA , Ryther KB , Sullivan JP , Arneric SP |
| Ref : Pharmacol Biochem Behav , 57 :231 , 1997 |
| Abstract : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| ESTHER : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| PubMedSearch : Briggs_1997_Pharmacol.Biochem.Behav_57_231 |
| PubMedID: 9164577 |
| Title : Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties - Lin_1997_J.Med.Chem_40_385 |
| Author(s) : Lin NH , Gunn DE , Ryther KB , Garvey DS , Donnelly-Roberts D , Decker MW , Brioni JD , Buckley MJ , Rodrigues AD , Marsh KG , Anderson DJ , Buccafusco JJ , Prendergast MA , Sullivan JP , Williams M , Arneric SP , Holladay MW |
| Ref : Journal of Medicinal Chemistry , 40 :385 , 1997 |
| Abstract : Lin_1997_J.Med.Chem_40_385 |
| ESTHER : Lin_1997_J.Med.Chem_40_385 |
| PubMedSearch : Lin_1997_J.Med.Chem_40_385 |
| PubMedID: 9022806 |
| Title : A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand - Sullivan_1996_Neuropharmacol_35_725 |
| Author(s) : Sullivan JP , Donnelly-Roberts D , Briggs CA , Anderson DJ , Gopalakrishnan M , Piattoni-Kaplan M , Campbell JE , McKenna DG , Molinari E , Hettinger AM , Garvey DS , Wasicak JT , Holladay MW , Williams M , Arneric SP |
| Ref : Neuropharmacology , 35 :725 , 1996 |
| Abstract : Sullivan_1996_Neuropharmacol_35_725 |
| ESTHER : Sullivan_1996_Neuropharmacol_35_725 |
| PubMedSearch : Sullivan_1996_Neuropharmacol_35_725 |
| PubMedID: 8887981 |
| Title : Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor - Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
| Author(s) : Gopalakrishnan M , Monteggia LM , Anderson DJ , Molinari EJ , Piattoni-Kaplan M , Donnelly-Roberts D , Arneric SP , Sullivan JP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 276 :289 , 1996 |
| Abstract : Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
| ESTHER : Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
| PubMedSearch : Gopalakrishnan_1996_J.Pharmacol.Exp.Ther_276_289 |
| PubMedID: 8558445 |
| Title : Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors - Abreo_1996_J.Med.Chem_39_817 |
| Author(s) : Abreo MA , Lin NH , Garvey DS , Gunn DE , Hettinger AM , Wasicak JT , Pavlik PA , Martin YC , Donnelly-Roberts D , Anderson DJ , Sullivan JP , Williams M , Arneric SP , Holladay MW |
| Ref : Journal of Medicinal Chemistry , 39 :817 , 1996 |
| Abstract : Abreo_1996_J.Med.Chem_39_817 |
| ESTHER : Abreo_1996_J.Med.Chem_39_817 |
| PubMedSearch : Abreo_1996_J.Med.Chem_39_817 |
| PubMedID: 8632405 |
| Title : Cholinergic channel activators: novel opportunities for the treatment of CNS disorders - Sullivan_1995_Proc.West.Pharmacol.Soc_38_127 |
| Author(s) : Sullivan JP , Decker MW , Donnelly-Roberts D , Brioni JD , Bannon AW , Holladay MW , Anderson DJ , Briggs CA , Williams M , Arneric SP |
| Ref : Proc West Pharmacol Soc , 38 :127 , 1995 |
| Abstract : Sullivan_1995_Proc.West.Pharmacol.Soc_38_127 |
| ESTHER : Sullivan_1995_Proc.West.Pharmacol.Soc_38_127 |
| PubMedSearch : Sullivan_1995_Proc.West.Pharmacol.Soc_38_127 |
| PubMedID: 7480004 |
| Title : Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors - Decker_1995_Eur.J.Pharmacol_280_79 |
| Author(s) : Decker MW , Anderson DJ , Brioni JD , Donnelly-Roberts D , Kang CH , O'Neill AB , Piattoni-Kaplan M , Swanson S , Sullivan JP |
| Ref : European Journal of Pharmacology , 280 :79 , 1995 |
| Abstract : Decker_1995_Eur.J.Pharmacol_280_79 |
| ESTHER : Decker_1995_Eur.J.Pharmacol_280_79 |
| PubMedSearch : Decker_1995_Eur.J.Pharmacol_280_79 |
| PubMedID: 7498257 |
| Title : Characterization of [3H]ABT-418: a novel cholinergic channel ligand - Anderson_1995_J.Pharmacol.Exp.Ther_273_1434 |
| Author(s) : Anderson DJ , Williams M , Pauly JR , Raszkiewicz JL , Campbell JE , Rotert G , Surber B , Thomas SB , Wasicak J , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 273 :1434 , 1995 |
| Abstract : Anderson_1995_J.Pharmacol.Exp.Ther_273_1434 |
| ESTHER : Anderson_1995_J.Pharmacol.Exp.Ther_273_1434 |
| PubMedSearch : Anderson_1995_J.Pharmacol.Exp.Ther_273_1434 |
| PubMedID: 7791118 |
| Title : (+\/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors - Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| Author(s) : Sullivan JP , Decker MW , Brioni JD , Donnelly-Roberts D , Anderson DJ , Bannon AW , Kang CH , Adams P , Piattoni-Kaplan M , Buckley MJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 271 :624 , 1994 |
| Abstract : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| ESTHER : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| PubMedSearch : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624 |
| PubMedID: 7965777 |
| Title : (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization - Arneric_1994_J.Pharmacol.Exp.Ther_270_310 |
| Author(s) : Arneric SP , Sullivan JP , Briggs CA , Donnelly-Roberts D , Anderson DJ , Raszkiewicz JL , Hughes ML , Cadman ED , Adams P , Garvey DS |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 270 :310 , 1994 |
| Abstract : Arneric_1994_J.Pharmacol.Exp.Ther_270_310 |
| ESTHER : Arneric_1994_J.Pharmacol.Exp.Ther_270_310 |
| PubMedSearch : Arneric_1994_J.Pharmacol.Exp.Ther_270_310 |
| PubMedID: 7518514 |
| Title : Non-selectivity of amitriptyline for subtypes of brain muscarinic receptors demonstrated in binding and functional assays - McKinney_1988_Eur.J.Pharmacol_157_51 |
| Author(s) : McKinney M , Lee NH , Anderson DJ , Vella-Rountree L , El-Fakahany EE |
| Ref : European Journal of Pharmacology , 157 :51 , 1988 |
| Abstract : McKinney_1988_Eur.J.Pharmacol_157_51 |
| ESTHER : McKinney_1988_Eur.J.Pharmacol_157_51 |
| PubMedSearch : McKinney_1988_Eur.J.Pharmacol_157_51 |
| PubMedID: 2853074 |
| Title : Transmembrane orientation of an early biosynthetic form of acetylcholine receptor delta subunit determined by proteolytic dissection in conjunction with monoclonal antibodies - Anderson_1983_J.Neurosci_3_1773 |
| Author(s) : Anderson DJ , Blobel G , Tzartos SJ , Gullick W , Lindstrom JM |
| Ref : Journal of Neuroscience , 3 :1773 , 1983 |
| Abstract : Anderson_1983_J.Neurosci_3_1773 |
| ESTHER : Anderson_1983_J.Neurosci_3_1773 |
| PubMedSearch : Anderson_1983_J.Neurosci_3_1773 |
| PubMedID: 6193254 |