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| Title : Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme - Shenoy_2020_Mol.Pharm_17_1706 |
| Author(s) : Shenoy VM , Thompson BR , Shi J , Zhu HJ , Smith DE , Amidon GL |
| Ref : Mol Pharm , 17 :1706 , 2020 |
| Abstract : Shenoy_2020_Mol.Pharm_17_1706 |
| ESTHER : Shenoy_2020_Mol.Pharm_17_1706 |
| PubMedSearch : Shenoy_2020_Mol.Pharm_17_1706 |
| PubMedID: 32196348 |
| Gene_locus related to this paper: human-RBBP9 |
| Title : Effect of biphenyl hydrolase-like (BPHL) gene disruption on the intestinal stability, permeability and absorption of valacyclovir in wildtype and Bphl knockout mice - Hu_2018_Biochem.Pharmacol_156_147 |
| Author(s) : Hu Y , Epling D , Shi J , Song F , Tsume Y , Zhu HJ , Amidon GL , Smith DE |
| Ref : Biochemical Pharmacology , 156 :147 , 2018 |
| Abstract : Hu_2018_Biochem.Pharmacol_156_147 |
| ESTHER : Hu_2018_Biochem.Pharmacol_156_147 |
| PubMedSearch : Hu_2018_Biochem.Pharmacol_156_147 |
| PubMedID: 30121252 |
| Gene_locus related to this paper: human-BPHL |
| Title : Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes - Xu_2015_Mol.Pharm_12_3399 |
| Author(s) : Xu H , Majmudar JD , Davda D , Ghanakota P , Kim KH , Carlson HA , Showalter HD , Martin BR , Amidon GL |
| Ref : Mol Pharm , 12 :3399 , 2015 |
| Abstract : Xu_2015_Mol.Pharm_12_3399 |
| ESTHER : Xu_2015_Mol.Pharm_12_3399 |
| PubMedSearch : Xu_2015_Mol.Pharm_12_3399 |
| PubMedID: 26262434 |
| Gene_locus related to this paper: human-CES1 |
| Title : Specificity of a prodrug-activating enzyme hVACVase: the leaving group effect - Sun_2010_Mol.Pharm_7_2362 |
| Author(s) : Sun J , Dahan A , Walls ZF , Lai L , Lee KD , Amidon GL |
| Ref : Mol Pharm , 7 :2362 , 2010 |
| Abstract : Sun_2010_Mol.Pharm_7_2362 |
| ESTHER : Sun_2010_Mol.Pharm_7_2362 |
| PubMedSearch : Sun_2010_Mol.Pharm_7_2362 |
| PubMedID: 21028903 |
| Gene_locus related to this paper: human-BPHL |
| Title : Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase - Lai_2008_J.Biol.Chem_283_9318 |
| Author(s) : Lai L , Xu Z , Zhou J , Lee KD , Amidon GL |
| Ref : Journal of Biological Chemistry , 283 :9318 , 2008 |
| Abstract : Lai_2008_J.Biol.Chem_283_9318 |
| ESTHER : Lai_2008_J.Biol.Chem_283_9318 |
| PubMedSearch : Lai_2008_J.Biol.Chem_283_9318 |
| PubMedID: 18256025 |
| Gene_locus related to this paper: human-BPHL |
| Title : Nucleoside ester prodrug substrate specificity of liver carboxylesterase - Landowski_2006_J.Pharmacol.Exp.Ther_316_572 |
| Author(s) : Landowski CP , Lorenzi PL , Song X , Amidon GL |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 316 :572 , 2006 |
| Abstract : Landowski_2006_J.Pharmacol.Exp.Ther_316_572 |
| ESTHER : Landowski_2006_J.Pharmacol.Exp.Ther_316_572 |
| PubMedSearch : Landowski_2006_J.Pharmacol.Exp.Ther_316_572 |
| PubMedID: 16223870 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport - Song_2005_Mol.Pharm_2_157 |
| Author(s) : Song X , Lorenzi PL , Landowski CP , Vig BS , Hilfinger JM , Amidon GL |
| Ref : Mol Pharm , 2 :157 , 2005 |
| Abstract : Song_2005_Mol.Pharm_2_157 |
| ESTHER : Song_2005_Mol.Pharm_2_157 |
| PubMedSearch : Song_2005_Mol.Pharm_2_157 |
| PubMedID: 15804190 |
| Title : Structure and specificity of a human valacyclovir activating enzyme: a homology model of BPHL - Kim_2004_Mol.Pharm_1_434 |
| Author(s) : Kim I , Crippen GM , Amidon GL |
| Ref : Mol Pharm , 1 :434 , 2004 |
| Abstract : Kim_2004_Mol.Pharm_1_434 |
| ESTHER : Kim_2004_Mol.Pharm_1_434 |
| PubMedSearch : Kim_2004_Mol.Pharm_1_434 |
| PubMedID: 16028355 |
| Title : A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein - Kim_2004_Mol.Pharm_1_117 |
| Author(s) : Kim I , Song X , Vig BS , Mittal S , Shin HC , Lorenzi PJ , Amidon GL |
| Ref : Mol Pharm , 1 :117 , 2004 |
| Abstract : Kim_2004_Mol.Pharm_1_117 |
| ESTHER : Kim_2004_Mol.Pharm_1_117 |
| PubMedSearch : Kim_2004_Mol.Pharm_1_117 |
| PubMedID: 15832508 |
| Gene_locus related to this paper: human-BPHL |
| Title : Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase - Kim_2003_J.Biol.Chem_278_25348 |
| Author(s) : Kim I , Chu XY , Kim S , Provoda CJ , Lee KD , Amidon GL |
| Ref : Journal of Biological Chemistry , 278 :25348 , 2003 |
| Abstract : Kim_2003_J.Biol.Chem_278_25348 |
| ESTHER : Kim_2003_J.Biol.Chem_278_25348 |
| PubMedSearch : Kim_2003_J.Biol.Chem_278_25348 |
| PubMedID: 12732646 |
| Gene_locus related to this paper: human-BPHL |