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| Title : Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase - Lindgren_2022_Chemistry_28_e202200678 |
| Author(s) : Lindgren C , Forsgren N , Hoster N , Akfur C , Artursson E , Edvinsson L , Svensson R , Worek F , Ekstrom , Linusson A |
| Ref : Chemistry , 28 :e202200678 , 2022 |
| Abstract : Lindgren_2022_Chemistry_28_e202200678 |
| ESTHER : Lindgren_2022_Chemistry_28_e202200678 |
| PubMedSearch : Lindgren_2022_Chemistry_28_e202200678 |
| PubMedID: 35420233 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Ammonia exposure by intratracheal instillation causes severe and deteriorating lung injury and vascular effects in mice - Elfsmark_2022_Inhal.Toxicol_34_145 |
| Author(s) : Elfsmark L , gren L , Akfur C , Jonasson S |
| Ref : Inhal Toxicol , 34 :145 , 2022 |
| Abstract : Elfsmark_2022_Inhal.Toxicol_34_145 |
| ESTHER : Elfsmark_2022_Inhal.Toxicol_34_145 |
| PubMedSearch : Elfsmark_2022_Inhal.Toxicol_34_145 |
| PubMedID: 35452355 |
| Title : An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet - Allgardsson_2017_Molecules_22_ |
| Author(s) : Allgardsson A , David Andersson C , Akfur C , Worek F , Linusson A , Ekstrom F |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Allgardsson_2017_Molecules_22_ |
| ESTHER : Allgardsson_2017_Molecules_22_ |
| PubMedSearch : Allgardsson_2017_Molecules_22_ |
| PubMedID: 28867801 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6 - Allgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514 |
| Author(s) : Allgardsson A , Berg L , Akfur C , Hornberg A , Worek F , Linusson A , Ekstrom F |
| Ref : Proc Natl Acad Sci U S A , 113 :5514 , 2016 |
| Abstract : Allgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514 |
| ESTHER : Allgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514 |
| PubMedSearch : Allgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514 |
| PubMedID: 27140636 |
| Gene_locus related to this paper: human-ACHE |
| Title : Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase - Andersson_2015_J.Comput.Aided.Mol.Des_29_199 |
| Author(s) : Andersson CD , Hillgren JM , Lindgren C , Qian W , Akfur C , Berg L , Ekstrom F , Linusson A |
| Ref : J Comput Aided Mol Des , 29 :199 , 2015 |
| Abstract : Andersson_2015_J.Comput.Aided.Mol.Des_29_199 |
| ESTHER : Andersson_2015_J.Comput.Aided.Mol.Des_29_199 |
| PubMedSearch : Andersson_2015_J.Comput.Aided.Mol.Des_29_199 |
| PubMedID: 25351962 |
| Title : Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors - Andersson_2013_J.Med.Chem_56_7615 |
| Author(s) : Andersson CD , Forsgren N , Akfur C , Allgardsson A , Berg L , Engdahl C , Qian W , Ekstrom F , Linusson A |
| Ref : Journal of Medicinal Chemistry , 56 :7615 , 2013 |
| Abstract : Andersson_2013_J.Med.Chem_56_7615 |
| ESTHER : Andersson_2013_J.Med.Chem_56_7615 |
| PubMedSearch : Andersson_2013_J.Med.Chem_56_7615 |
| PubMedID: 23984975 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: possible implications for the HI-6 antidote substrate specificity - Artursson_2013_Biochem.Pharmacol_85_1389 |
| Author(s) : Artursson E , Andersson PO , Akfur C , Linusson A , Borjegren S , Ekstrom F |
| Ref : Biochemical Pharmacology , 85 :1389 , 2013 |
| Abstract : Artursson_2013_Biochem.Pharmacol_85_1389 |
| ESTHER : Artursson_2013_Biochem.Pharmacol_85_1389 |
| PubMedSearch : Artursson_2013_Biochem.Pharmacol_85_1389 |
| PubMedID: 23376121 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis - Artursson_2009_Toxicology_265_108 |
| Author(s) : Artursson E , Akfur C , Hornberg A , Worek F , Ekstrom F |
| Ref : Toxicology , 265 :108 , 2009 |
| Abstract : Artursson_2009_Toxicology_265_108 |
| ESTHER : Artursson_2009_Toxicology_265_108 |
| PubMedSearch : Artursson_2009_Toxicology_265_108 |
| PubMedID: 19761810 |
| Title : Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates - Ekstrom_2006_Biochem.Pharmacol_72_597 |
| Author(s) : Ekstrom F , Pang YP , Boman M , Artursson E , Akfur C , Borjegren S |
| Ref : Biochemical Pharmacology , 72 :597 , 2006 |
| Abstract : Ekstrom_2006_Biochem.Pharmacol_72_597 |
| ESTHER : Ekstrom_2006_Biochem.Pharmacol_72_597 |
| PubMedSearch : Ekstrom_2006_Biochem.Pharmacol_72_597 |
| PubMedID: 16876764 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase - Ekstrom_2006_Biochemistry_45_74 |
| Author(s) : Ekstrom F , Akfur C , Tunemalm AK , Lundberg S |
| Ref : Biochemistry , 45 :74 , 2006 |
| Abstract : Ekstrom_2006_Biochemistry_45_74 |
| ESTHER : Ekstrom_2006_Biochemistry_45_74 |
| PubMedSearch : Ekstrom_2006_Biochemistry_45_74 |
| PubMedID: 16388582 |
| Gene_locus related to this paper: mouse-ACHE |