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Author Report for: Akaike A

Contact information:

Akaike Akinori
Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501
Japan
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    Title: Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons
    Takada-Takatori Y, Nakagawa S, Kimata R, Nao Y, Mizukawa Y, Urushidani T, Izumi Y, Akaike A, Tsuchida K, Kume T
    Ref: Sci Rep, 9:11922, 2019 : PubMed

            

    Title: Inhibitory effect of donepezil on bradykinin-induced increase in the intracellular calcium concentration in cultured cortical astrocytes
    Makitani K, Nakagawa S, Izumi Y, Akaike A, Kume T
    Ref: J Pharmacol Sci, 134:37, 2017 : PubMed

            

    Title: Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection
    Akaike A, Takada-Takatori Y, Kume T, Izumi Y
    Ref: Journal of Molecular Neuroscience, 40:211, 2010 : PubMed

            

    Title: Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors
    Shen H, Kihara T, Hongo H, Wu X, Kem WR, Shimohama S, Akaike A, Niidome T, Sugimoto H
    Ref: British Journal of Pharmacology, 161:127, 2010 : PubMed

            

    Title: Mechanisms of chronic nicotine treatment-induced enhancement of the sensitivity of cortical neurons to the neuroprotective effect of donepezil in cortical neurons
    Takada-Takatori Y, Kume T, Izumi Y, Niidome T, Fujii T, Sugimoto H, Akaike A
    Ref: J Pharmacol Sci, 112:265, 2010 : PubMed

            

    Title: Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors
    Takahashi J, Hijikuro I, Kihara T, Murugesh MG, Fuse S, Kunimoto R, Tsumura Y, Akaike A, Niidome T and Sugimoto H <2 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 20:1718, 2010 : PubMed

            

    Title: Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors
    Takahashi J, Hijikuro I, Kihara T, Murugesh MG, Fuse S, Tsumura Y, Akaike A, Niidome T, Takahashi T, Sugimoto H
    Ref: Bioorganic & Medicinal Chemistry Lett, 20:1721, 2010 : PubMed

            

    Title: Long-term treatment with nicotine suppresses neurotoxicity of, and microglial activation by, thrombin in cortico-striatal slice cultures
    Ohnishi M, Katsuki H, Takagi M, Kume T, Akaike A
    Ref: European Journal of Pharmacology, 602:288, 2009 : PubMed

            

    Title: Roles of nicotinic receptors in acetylcholinesterase inhibitor-induced neuroprotection and nicotinic receptor up-regulation
    Takada-Takatori Y, Kume T, Izumi Y, Ohgi Y, Niidome T, Fujii T, Sugimoto H, Akaike A
    Ref: Biol Pharm Bull, 32:318, 2009 : PubMed

            

    Title: Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models
    Takeuchi H, Yanagida T, Inden M, Takata K, Kitamura Y, Yamakawa K, Sawada H, Izumi Y, Yamamoto N and Shimohama S <6 more author(s)>
    Ref: Journal of Neuroscience Research, 87:576, 2009 : PubMed

            

    Title: Donepezil attenuates excitotoxic damage induced by membrane depolarization of cortical neurons exposed to veratridine
    Akasofu S, Sawada K, Kosasa T, Hihara H, Ogura H, Akaike A
    Ref: European Journal of Pharmacology, 588:189, 2008 : PubMed

            

    Title: Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease
    Goto Y, Niidome T, Hongo H, Akaike A, Kihara T, Sugimoto H
    Ref: European Journal of Pharmacology, 583:84, 2008 : PubMed

            

    Title: Mechanisms of alpha7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment
    Takada-Takatori Y, Kume T, Ohgi Y, Fujii T, Niidome T, Sugimoto H, Akaike A
    Ref: European Journal of Pharmacology, 590:150, 2008 : PubMed

            

    Title: Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil
    Takada-Takatori Y, Kume T, Ohgi Y, Izumi Y, Niidome T, Fujii T, Sugimoto H, Akaike A
    Ref: Journal of Neuroscience Research, 86:3575, 2008 : PubMed

            

    Title: Donepezil potentiates nerve growth factor-induced neurite outgrowth in PC12 cells
    Oda T, Kume T, Katsuki H, Niidome T, Sugimoto H, Akaike A
    Ref: J Pharmacol Sci, 104:349, 2007 : PubMed

            

    Title: Preclinical evidence of neuroprotection by cholinesterase inhibitors
    Akaike A
    Ref: Alzheimer Disease & Associated Disorders, 20:S8, 2006 : PubMed

            

    Title: Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity
    Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Niidome T, Sugimoto H, Fujii T, Okabe S, Akaike A
    Ref: European Journal of Pharmacology, 549:19, 2006 : PubMed

            

    Title: Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade
    Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Sugimoto H, Akaike A
    Ref: Neuropharmacology, 51:474, 2006 : PubMed

            

    Title: Tetraethylammonium exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures
    Katsuki H, Shinohara A, Fujimoto S, Kume T, Akaike A
    Ref: European Journal of Pharmacology, 508:85, 2005 : PubMed

            

    Title: Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons
    Kume T, Sugimoto M, Takada Y, Yamaguchi T, Yonezawa A, Katsuki H, Sugimoto H, Akaike A
    Ref: European Journal of Pharmacology, 527:77, 2005 : PubMed

            

    Title: Stimulation of nicotinic acetylcholine receptors protects motor neurons
    Nakamizo T, Kawamata J, Yamashita H, Kanki R, Kihara T, Sawada H, Akaike A, Shimohama S
    Ref: Biochemical & Biophysical Research Communications, 330:1285, 2005 : PubMed

            

    Title: Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons
    Takada Y, Yonezawa A, Kume T, Katsuki H, Kaneko S, Sugimoto H, Akaike A
    Ref: Journal of Pharmacology & Experimental Therapeutics, 306:772, 2003 : PubMed

            

    Title: alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, Kume T, Akaike A
    Ref: Journal of Biological Chemistry, 276:13541, 2001 : PubMed

            

    Title: Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity
    Kihara T, Shimohama S, Urushitani M, Sawada H, Kimura J, Kume T, Maeda T, Akaike A
    Ref: Brain Research, 792:331, 1998 : PubMed

            

    Title: Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors
    Kaneko S, Maeda T, Kume T, Kochiyama H, Akaike A, Shimohama S, Kimura J
    Ref: Brain Research, 765:135, 1997 : PubMed

            

    Title: Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity
    Kihara T, Shimohama S, Sawada H, Kimura J, Kume T, Kochiyama H, Maeda T, Akaike A
    Ref: Annals of Neurology, 42:159, 1997 : PubMed

            

    Title: Activation and Inhibition of the Nicotinic Receptor: Actions of Physostigmine, Pyridostigmine and Meproadifen
    Albuquerque EX, Allen CN, Aracava Y, Akaike A, Shaw KP, Rickett DL
    Ref: Advances in Behavioral Biology, 30:677, 1986 : PubMed

            

    Title: The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex
    Shaw KP, Aracava Y, Akaike A, Daly JW, Rickett DL, Albuquerque EX
    Ref: Molecular Pharmacology, 28:527, 1985 : PubMed

            

    Title: The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. II. Patch clamp studies
    Akaike A, Ikeda SR, Brookes N, Pascuzzo GJ, Rickett DL, Albuquerque EX
    Ref: Molecular Pharmacology, 25:102, 1984 : PubMed

            

    Title: The interaction of anticholinesterase agents with the acetylcholine receptor-ionic channel complex
    Albuquerque EX, Akaike A, Shaw KP, Rickett DL
    Ref: Fundamental & Applied Toxicology, 4:S27, 1984 : PubMed

            

    Title: The frog interosseal muscle fiber as a new model for patch clamp studies of chemosensitive- and voltage-sensitive ion channels: actions of acetylcholine and batrachotoxin
    Allen CN, Akaike A, Albuquerque EX
    Ref: Journal de Physiologie (Paris), 79:338, 1984 : PubMed

            

    Title: The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing, and binding properties
    Pascuzzo GJ, Akaike A, Maleque MA, Shaw KP, Aronstam RS, Rickett DL, Albuquerque EX
    Ref: Molecular Pharmacology, 25:92, 1984 : PubMed

            


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