for example to search all human alpha/beta hydrolase found in human genome enter this search in the window below:
select a, fam, nam, c from a in class Gene_locus,
spec in a->Species where spec.name like "Homo sapiens",
fam in a->Family,
nam in a->Name,
c in count(select a->Structure)
sort by: fam, :nam

for more examples from esther go to AQL esther
for examples from esther on insecticide resistance go to AQL esther resistance
for more examples from wormbase go to AQL wormbase
AQL for the supplementary material of the Pucon Poster Pucon Poster
 
51 rows returned
Torpedo_number Mutation Text Paper
10 V12T_human-ACHE p.V12T Val12Thr (p.V43T Val43Thr in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Thr as in ACHE (Torpedo, Bungar) and human BCHE Goldenzweig_2016_Mol.Cell_63_337
21 K23T_human-ACHE p.K23T Lys23Thr (p.K54T Lys54Thr in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Thr as in human BCHE and drosophila ACHE Goldenzweig_2016_Mol.Cell_63_337
40 M42V_human-ACHE p.M42V Met42Val (p.M73V Met73Val in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Val as in Torpedo californica Mouse and drosophila AChE Goldenzweig_2016_Mol.Cell_63_337
46 L48R_human-ACHE p.L48R Leu48Arg (p.L79R Leu79Arg in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Arg as in Torpedo californica and drosophila AChE Goldenzweig_2016_Mol.Cell_63_337
58 V60W_human-ACHE p.V60W Val60Trp (p.V91W Val91Trp in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Arg as in Torpedo californica AChE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
65 S67N_human-ACHE p.S67N Ser67Asn (p.S98N Ser98Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asn as in Torpedo californica and mouse AChE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
89 E91N_human-ACHE p.E91N Glu91Asn (p.E122N Glu122Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asn Glu Conserved in ACHE N in Drosophila AChE Goldenzweig_2016_Mol.Cell_63_337
107 T109K_human-ACHE p.T109K Thr109Lys (p.T140K Thr140Lys in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Lys as in Torpedo ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
108 S110N_human-ACHE p.S110N Ser110Asn (p.S141N Ser141Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asn as in human BCHE Goldenzweig_2016_Mol.Cell_63_337
110 T112A_human-ACHE p.T112A Thr112Ala (p.T143A Thr143Ala in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ala as in Torpedo californica AChE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
112 L115M_human-ACHE p.L115M Leu115Met (p.L146M Leu146Met in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Met as in Torpedo californica AChE Goldenzweig_2016_Mol.Cell_63_337
124 A127S_human-ACHE p.A127S Ala127Ser (p.A158S Ala158Ser in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ser as in Torpedo californica and Drosophila AChE Goldenzweig_2016_Mol.Cell_63_337
137 Q140R_human-ACHE p.Q140R Gln140Arg (p.Q171R Gln171Arg in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Arg as in human BCHE Goldenzweig_2016_Mol.Cell_63_337
138 A141T_human-ACHE p.A141T Ala141Thr (p.A172T Ala172Thr in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Thr as in Torpedo californica and Bungar ACHE Goldenzweig_2016_Mol.Cell_63_337
141 T144V_human-ACHE p.T144V Thr144Val (p.T175V Thr175Val in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Val as in Torpedo californica and Bungar ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
184 V187I_human-ACHE p.V187I Val187Ile (p.V218I Val218Ile in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ile as in Torpedo californica mouse Bungar ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
223 V226I_human-ACHE p.V226I Val226Ile (p.V257I Val257Ile in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ile as in Torpedo californica Bungar ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
231 G234A_human-ACHE p.G234A Gly234Ala (p.G265A Gly265Ala in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ala as in Bungar ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
235 T238Y_human-ACHE p.T238Y Thr238Tyr (p.T269Y Thr269Tyr in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. Goldenzweig_2016_Mol.Cell_63_337
237 G240S_human-ACHE p.G240S Gly240Ser (p.G271S Gly271Ser in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ser as Torpedo californica mouse ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
238 M241R_human-ACHE p.M241R Met241Arg (p.M272R Met272Arg in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. Goldenzweig_2016_Mol.Cell_63_337
239 G242E_human-ACHE p.G242E Gly242Glu (p.G273E Gly273Glu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Glu as in Drosophila ACHE Goldenzweig_2016_Mol.Cell_63_337
246 T249L_human-ACHE p.T249L Thr249Leu (p.T280L Thr280Leu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Leu as in human BCHE Goldenzweig_2016_Mol.Cell_63_337
250 H253K_human-ACHE p.H253K His253Lys (p.H284K His284Lys in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Lys as in human BCHE Goldenzweig_2016_Mol.Cell_63_337
268 T275N_human-ACHE p.T275N Thr275Asn (p.T306N Thr306Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asn as in human BCHE Goldenzweig_2016_Mol.Cell_63_337
271 A278P_human-ACHE p.A278P Ala278Pro (p.A309P Ala309Pro in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Pro as in Torpedo californica and bungar ACHE human BCHE Goldenzweig_2016_Mol.Cell_63_337
273 V280E_human-ACHE p.V280E Val280Glu (p.V311E Val311Glu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Glu as in Torpedo californica and bungar ACHE human BCHE Goldenzweig_2016_Mol.Cell_63_337
302 S309P_human-ACHE p.S309P Ser309Pro (p.S340P Ser340Pro in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Pro as in Torpedo californica Drosophila and bungar ACHE Goldenzweig_2016_Mol.Cell_63_337
311 A318N_human-ACHE p.A318N Ala318Asn (p.A349N Ala349Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. Goldenzweig_2016_Mol.Cell_63_337
315 H322K_human-ACHE p.H322K His322Lys (p.H353K His353Lys in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Lys as in Torpedo californica Drosophila and bungar ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
318 Q325D_human-ACHE p.Q325D Gln325Asp (p.Q356D Gln356Asp in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asp as in Drosophila ACHE Goldenzweig_2016_Mol.Cell_63_337
323 V331N_human-ACHE p.V331N Val331Asn (p.V362N Val362Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asn as in Drosophila ACHE Goldenzweig_2016_Mol.Cell_63_337
350 A357E_human-ACHE p.A357E Ala357Glu (p.A388E Ala388Glu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Glu as in Torpedo californica ACHE Goldenzweig_2016_Mol.Cell_63_337
354 A361E_human-ACHE p.A361E Ala361Glu (p.A392E Ala392Glu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Glu as in Bunfa ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
371 V378I_human-ACHE p.V378I Val378Ile (p.V409I Val409Ile in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ile as in Drosophila ACHE and human BCHE Goldenzweig_2016_Mol.Cell_63_337
386 R393K_human-ACHE p.R393K Arg393Lys (p.R424K Arg424Lys in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Lys as in Torpedo californica and Bungar ACHE Goldenzweig_2016_Mol.Cell_63_337
387 L394N_human-ACHE p.L394N Leu394Asn (p.L425N Leu425Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asn as in Torpedo californica Bungar and Drosophila ACHE Goldenzweig_2016_Mol.Cell_63_337
389 E396D_human-ACHE p.E396D Glu396Asp (p.E427D Glu427Asp in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Asp as in Torpedo californica mouse ACHE Goldenzweig_2016_Mol.Cell_63_337
401 V408I_human-ACHE p.V408I Val408Ile (p.V439I Val439Ile in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ile as in Torpedo californica Bunfa ACHE and human BChE Goldenzweig_2016_Mol.Cell_63_337
407 L414F_human-ACHE p.L414F Leu414Phe (p.L445F Leu445Phe in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Phe as in Torpedo californica Bunfa ACHE and human BChE Goldenzweig_2016_Mol.Cell_63_337
409 G416Q_human-ACHE p.G416Q Gly416Gln (p.G447Q Gly447Gln in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Gln as in Drosophila ACHE Goldenzweig_2016_Mol.Cell_63_337
411 L418Y_human-ACHE p.L418Y Leu418Tyr (p.L449Y Leu449Tyr in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Tyr as in Torpedo californica and Bungar ACHE Goldenzweig_2016_Mol.Cell_63_337
414 Q421N_human-ACHE p.Q421N Gln421Asn (p.Q452N Gln452Asn in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. Goldenzweig_2016_Mol.Cell_63_337
427 A434S_human-ACHE p.A434S Ala434Ser (p.A465S Ala465Ser in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Ser as in Human BCHE Goldenzweig_2016_Mol.Cell_63_337
431 S438P_human-ACHE p.S438P Ser438Pro (p.S469P Ser469Pro in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Pro as in Human BCHE Goldenzweig_2016_Mol.Cell_63_337
434 L441E_human-ACHE p.L441E Leu441Glu (p.L472E Leu472Glu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Glu as in Torpedo californica AChE and Human BCHE Goldenzweig_2016_Mol.Cell_63_337
460 A467K_human-ACHE p.A467K Ala467Lys (p.A498K Ala498Lys in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Lys as in Human BCHE Goldenzweig_2016_Mol.Cell_63_337
467 Q474R_human-ACHE p.Q474R Gln474Arg (p.Q505R Gln505Arg in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Arg as in Torpedo californica Bunfa AChE and in Human BCHE Goldenzweig_2016_Mol.Cell_63_337
498 G506D_human-ACHE p.G506D Gly506Asp (p.G537D Gly537Asp in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. Goldenzweig_2016_Mol.Cell_63_337
499 A507E_human-ACHE p.A507E Ala507Glu (p.A538E Ala538Glu in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Glu as in Torpedo californica AChE and Human BCHE Goldenzweig_2016_Mol.Cell_63_337
501 Q509K_human-ACHE p.Q509K Gln509Lys (p.Q540K Gln540Lys in primary sequence with 31 amino-acids signal peptide) mutation designed by -Protein Repair One Stop Shop- process for the production of active human acetylcholinesterase in a prokaryotic system. The mutation gives Lys as in Torpedo californica AChE and Human BCHE Goldenzweig_2016_Mol.Cell_63_337

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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