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Type_inhibitor Report for: Covalent inhibitor adduct

Adduct left on enzyme after elimination of leaving group. The adduct fixed on the active serine of inhibited enzyme is used as trace of the inhibitor used. However different inhibitors may leave the same adduct if they differ only by the leaving group. Same adduct for Paraoxon, DEUP, echothiophate

InhibitorMain targeted enzyme familiesTypeStructure
Diethyl-hydrogen-phosphate Covalent inhibitor adduct

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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