Acridine is a tricyclic compound (C13H9N) with a central pyridine cycle fused with two benzene. Several dyes and drugs feature the acridine skeleton Many acridines, such as proflavine, also have antiseptic properties. Acridine and related derivatives bind to DNA and RNA due to their abilities to intercalate. Tacrine (tetra trahydroaminacrine) was the first inhibitor of AChE used in Alzheimer's disease but has many side effects and is dicontinued