ESTHER
Database
Home
Search
Text search
aql query
In Class
Query Builder
Preformed queries
Species
Structures
Mutations
Interactants
Diseases
Genes
Insecticides
Other
Full List
Queries for insecticide resistance
AQL exemples
Tools
Blast
HMMER
Clustal
Psiblast
Intra
Families
Overall Table
Tree Table &
Old Table
Tree Table
Old Table
Explore genes with AQL
Explore species with AQL
All figures of families
Biological
data
Structures
Table
Explore structure with AQL
Mutations
Mutation Viewer
Mutalign
Mutalign 2
Mutalign for insecticide resistance
Queries for insecticide resistance
Explore mutation with AQL
Interactants
Substrates
Inhibitors
Reactivators
Kinetic comparison tool
Inhibitor types
Substrate types
Reactivator types
Explore interactants with AQL
Diseases
Table
Explore disease with AQL
Basics on AChE
Kinetics notes
Gene structures
Molecular forms
AChE Family
Human AChE
ESTHER definition
What is up?
Likid
DB Explorer
Meetings
Suplementary Data
Latest modifications
Bibliography (all years)
Acknowledgments
& disclaimer
Torpedo_number
Kinetic parameters
Tree Display
AceDB Schema
XML Display
Feedback
Torpedo_number Report for: 227
aedae-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
G285A
sdm
OP-resistance
OP-resistance Not yet found in nature
Vaughan_1997_Exp.Parasitol_87_237
F105S/
G285A
sdm
OP-resistance
OP-resistance Not yet found in nature
Vaughan_1997_Exp.Parasitol_87_237
G285A/
F350Y
sdm
OP-resistance
OP-resistance Not yet found in nature
Vaughan_1997_Exp.Parasitol_87_237
F105S/
G285A/
F350Y
sdm
OP-resistance
OP-resistance Not yet found in nature
Vaughan_1997_Exp.Parasitol_87_237
bommo-ACHE1
Mutation
Kin.
Type
Evaluation system
Effect
Reference
A303S/
G329A/
L554S
sdm
OP-resistance
Wang_2014_Mol.Biol.Rep_41_429
drome-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
G303A
sdm, nat
Insecticide sensitivity
Boublik_2002_Protein.Eng_15_43
G303A
sdm, nat
OP-resistance
Found associated other mutations in Saltillo Bygdea and Pierrefeu strains, high resistance only in combination
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_592
G303A
sdm, nat
Binding of Triton X-100 studies
no effect on Triton X-100 binding
Marcel_2000_J.Biol.Chem_275_11603
F115S/
I199V/
G303A
sdm
OP-resistance
OP-resistance lower than multiple,mut found in Saltillo strain together with I199V G303A F368Y
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
F115S/
G303A/
F368Y
sdm
OP-resistance
OP-resistance lower than multiple,mut found in Saltillo strain together with I199V G303A F368Y
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_592
F115S/
I199V/
G303A/
F368Y
nat
Natural mutation
Saltillo strain OP-resistance
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
I199V/
G303A
sdm, nat
OP-resistance
Bygdia strain and sdm OP-resistance
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
I199V/
G303A
sdm, nat
OP-resistance
Bygdia strain and sdm OP-resistance
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_592
I199T/
G303A
nat
OP-resistance
Pierrefeu strain OP-resistance
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
I199T/
G303A
nat
OP-resistance
Pierrefeu strain OP-resistance
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_592
I199V/
G303A/
F368Y
sdm
OP-resistance
Three mutations found in OP-resistant Saltillo strain
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_5922
G303A/
F368Y
sdm
OP-resistance
Found associated F115S and I199V mutations in Saltillo strain, high resistance for propoxure malaoxon and carbaryl
Mutero_1994_Proc.Natl.Acad.Sci.U.S.A_91_592
exoso-ACHE2
Mutation
Kin.
Type
Evaluation system
Effect
Reference
G353A
nat
OP-resistance
G353A
Lang_2010_BMB.Rep_43_573
haeir-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
G262A
nat
OP-resistance
Temeyer_2008_Vet.Parasitol_154_300
luccu-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
G303A
sdm
Insecticide sensitivity
Chen_2001_Insect.Biochem.Mol.Biol_31_805
I199V/
G303A/
F368Y
sdm
OP-resistance
Chen_2001_Insect.Biochem.Mol.Biol_31_805
G303A/
F368Y
sdm
OP-resistance
Chen_2001_Insect.Biochem.Mol.Biol_31_805
musdo-ACHE
Mutation
Kin.
Type
Evaluation system
Effect
Reference
V180L/
G262A
nat
OP-resistance
mutations found in strain resistant
Baskurt_2011_J.Vector.Ecol_36_248
V180L/
G262A/
F327Y
nat
OP-resistance
mutations found in the 77M strain resistant to methomyl
Walsh_2001_Biochem.J_359_175
V180L/
G262A/
F327Y
nat
OP-resistance
mutations found in the SH-CBR strain resistant to carbamate
Liming_2006_Pestic.Biochem.Physiol_86_1
V180L/
G262A/
F327Y
nat
OP-resistance
Baskurt_2011_J.Vector.Ecol_36_248
V180L/
G262A/
F327Y/
D341L
nat
OP-resistance
mutations found in the SH-CBR strain resistant to carbamate
Liming_2006_Pestic.Biochem.Physiol_86_1
V180L/
G262A/
F327Y/
D341L
nat
OP-resistance
Danish housefly strain 571ab from tokyo fenitrothion
Kristensen_2006_Pest.Manag.Sci_62_738
G262A/
F327Y
nat
OP-resistance
mutations found in the CH2 strain resistant to methomyl
Walsh_2001_Biochem.J_359_175
G262A/
F327Y
nat
OP-resistance
Danish housefly strain 690ab from Denmark methomyl
Kristensen_2006_Pest.Manag.Sci_62_738
G262A/
F327Y
nat
OP-resistance
Baskurt_2011_J.Vector.Ecol_36_248
G262V/
F327Y
nat
OP-resistance
mutations found in the 690ab strain resistant to methomyl
Walsh_2001_Biochem.J_359_175
G262V/
F327Y
nat
OP-resistance
Danish housefly strain 690ab Denmark methomyl
Kristensen_2006_Pest.Manag.Sci_62_738
G262V/
F327Y
nat
OP-resistance
Baskurt_2011_J.Vector.Ecol_36_248
T230M/
G262V/
F327Y/
A586T
nat
OP-resistance
Danish housefly strain 594vb Denmark azamethiphos 381zb Denmark multi resistant OP carbamate pyrthroid
Kristensen_2006_Pest.Manag.Sci_62_738
G262A
nat
OP-resistance
insensitivity to fenitroxon
Kozaki_2001_Insect.Biochem.Mol.Biol_31_991
G262V
nat
OP-resistance
insensitivity to fenitroxon
Kozaki_2001_Insect.Biochem.Mol.Biol_31_991
I82M/
G262A/
F327Y
nat
OP-resistance
restoring G262 and F327 restore sensitivity
Kim_2003_Mol.Cells_15_208
pluxy-ACHE1
Mutation
Kin.
Type
Evaluation system
Effect
Reference
G227A
nat
OP-resistance
G227A A201S A441G (G324A,A298S,A324G) found together in resistant strains but G227A likely to be important (also numbered G324A in Lee et al.)
Baek_2005_Pestic.Biochem.Physiol_81_164
G227A
nat
OP-resistance
D131G A201S A441G (D229G, A298S,A324G) found together in resistant strains but G227A likely to be important
Lee_2007_Biochem.Biophys.Res.Commun_353_591
G227A
nat
OP-resistance
G227A A201S (G324A,A298S) found together in resistant strains but A201S likely to be important
Kim_2012_J.Asia.Pac.Entomol_15_401
G227A
nat
OP-resistance
A298S and G324A mutations showed no correlation with levels of resistance to acephate
Sonoda_2014_Insect.Biochem.Mol.Biol_48_83
spolt-ACHE1
Mutation
Kin.
Type
Evaluation system
Effect
Reference
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page
and
ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster
Acknowledgements and disclaimer