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PAF-2-Thio

General

Type : Trimethylammonium || Choline ester

Chemical_Nomenclature : [(2R)-2-acetylsulfanyl-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

Canonical SMILES : CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)SC(=O)C

InChI : InChI=1S\/C26H54NO6PS\/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(35-25(2)28)24-33-34(29,30)32-22-20-27(3,4)5\/h26H,6-24H2,1-5H3\/t26-\/m1\/s1

InChIKey : YPPZOKNKENLFTE-AREMUKBSSA-N

Other name(s) : 2-thio PAF,     1-O-Hexadecyl-2-deoxy-2-thio-S-acetyl-sn-glyceryl-3-phosphorylcholine,     CHEBI:183981,     HMS3649A13,     HY-101263

MW : 539.74

Formula : C26H54NO6PS

CAS_number : 74389-68-7 || 96801-55-7

PubChem :

UniChem :

Iuphar :

Target

Families : PAF-Acetylhydrolase, LYsophospholipase_carboxylesterase

References (3)

Title : Lipoprotein-Associated Phospholipase A2 Activity as Potential Biomarker of Vascular Dementia - Zuliani_2023_Antioxidants.(Basel)_12_597
Author(s) : ZulianiZuliani G , Marsillach J , Trentini A , Rosta V , Cervellati C
Ref : Antioxidants (Basel) , 12 :597 , 2023
Abstract : Zuliani_2023_Antioxidants.(Basel)_12_597
ESTHER : Zuliani_2023_Antioxidants.(Basel)_12_597
PubMedSearch : Zuliani_2023_Antioxidants.(Basel)_12_597
PubMedID: 36978845
Gene_locus related to this paper: human-PLA2G7

Title : Catabolism of platelet-activating factor and its acyl analog. Differentiation of the activities of lysophospholipase and platelet- activating-factor acetylhydrolase - Aarsman_1991_Eur.J.Biochem_200_187
Author(s) : Aarsman AJ , Neys FW , Van den Bosch H
Ref : European Journal of Biochemistry , 200 :187 , 1991
Abstract : Aarsman_1991_Eur.J.Biochem_200_187
ESTHER : Aarsman_1991_Eur.J.Biochem_200_187
PubMedSearch : Aarsman_1991_Eur.J.Biochem_200_187
PubMedID: 1879423

Title : Structure-activity relationships for platelet-activating factor (PAF) and analogues reveal differences between PAF receptors on platelets and macrophages - Stewart_1991_J.Lipid.Mediat_4_299
Author(s) : Stewart AG , Grigoriadis G
Ref : J Lipid Mediat , 4 :299 , 1991
Abstract : Stewart_1991_J.Lipid.Mediat_4_299
ESTHER : Stewart_1991_J.Lipid.Mediat_4_299
PubMedSearch : Stewart_1991_J.Lipid.Mediat_4_299
PubMedID: 1662547