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Methyl-L-lactate

General

Type : Alkyl ester || Propionate

Chemical_Nomenclature : methyl (2S)-2-hydroxypropanoate

Canonical SMILES : CC(C(=O)OC)O

InChI : InChI=1S\/C4H8O3\/c1-3(5)4(6)7-2\/h3,5H,1-2H3\/t3-\/m0\/s1

InChIKey : LPEKGGXMPWTOCB-VKHMYHEASA-N

Other name(s) : Methyl (S)-(-)-lactate,     Methyl L-lactate,     (-)-Methyl L-lactate,     (S)-Methyl lactate,     (S)-Lactic acid methyl ester

MW : 104.10

Formula : C4H8O3

CAS_number : 27871-49-4

PubChem :

UniChem :

Iuphar :

Target

Families : Hormone-sensitive_lipase_like, LYsophospholipase_carboxylesterase

References (6)

Title : Characterization of one novel microbial esterase WDEst9 and its use to make l-methyl lactate - Wang_2019_Biocatal.Biotransformation_37_190
Author(s) : Wang Y , Xu S , Li R , Sun A , Zhang Y , Sai K , Hu Y
Ref : Biocatalysis and Biotransformation , 37 :190 , 2019
Abstract : Wang_2019_Biocatal.Biotransformation_37_190
ESTHER : Wang_2019_Biocatal.Biotransformation_37_190
PubMedSearch : Wang_2019_Biocatal.Biotransformation_37_190
PubMedID:
Gene_locus related to this paper: 9actn-a0a2d1pk72

Title : Determinants and prediction of esterase substrate promiscuity patterns - Martinez-Martinez_2018_ACS.Chem.Biol_13_225
Author(s) : Martinez-Martinez M , Coscolin C , Santiago G , Chow J , Stogios PJ , Bargiela R , Gertler C , Navarro-Fernandez J , Bollinger A , Thies S , Mendez-Garcia C , Popovic A , Brown G , Chernikova TN , Garcia-Moyano A , Bjergah GE , Perez-Garcia P , Hai T , Del Pozo MV , Stokke R , Steen IH , Cui H , Xu X , Nocek BP , Alcaide M , Distaso M , Mesa V , Pelaez AI , Sanchez J , Buchholz PCF , Pleiss J , Fernandez-Guerra A , Glockner FO , Golyshina OV , Yakimov MM , Savchenko A , Jaeger KE , Yakunin AF , Streit WR , Golyshin PN , Guallar V , Ferrer M
Ref : ACS Chemical Biology , 13 :225 , 2018
Abstract : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
ESTHER : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
PubMedSearch : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
PubMedID: 29182315
Gene_locus related to this paper: 9zzzz-a0a2k8jn75 , 9zzzz-a0a2k8jt94 , 9zzzz-a0a0g3fj44 , 9zzzz-a0a0g3fh10 , 9zzzz-a0a0g3fh03 , 9bact-a0a1s5qkj8 , 9zzzz-a0a0g3feh5 , 9zzzz-a0a0g3fkz4 , 9zzzz-a0a0g3fh07 , 9zzzz-a0a0g3fh34 , 9zzzz-a0a0g3fh31 , 9bact-KY458167 , alcbs-q0vqa3 , 9bact-a0a1s5qki8 , 9zzzz-a0a0g3feq8 , 9zzzz-a0a0g3feh8 , 9zzzz-a0a0g3fh19 , 9bact-KY203037 , 9bact-a0a1s5ql22 , 9bact-a0a1s5qm34 , 9bact-KY203034 , 9bact-r9qzg0 , 9bact-a0a1s5qly8 , 9zzzz-a0a0g3fkz8 , 9zzzz-a0a0g3feg9 , 9zzzz-KY203033 , 9zzzz-a0a0g3fes4 , 9zzzz-a0a0g3fh42 , 9bact-a0a1s5qlx2 , 9zzzz-KY483651 , 9bact-a0a1s5qmh4 , 9zzzz-KY203032 , 9zzzz-EH87 , 9zzzz-a0a0g3fei1 , 9zzzz-a0a0g3fet2 , 9zzzz-KY483647 , 9zzzz-EH82 , 9zzzz-a0a0g3fe15 , 9bact-KY203031 , 9bact-t1w006 , 9zzzz-a0a0g3fet6 , 9bact-KY458164 , geoth-g8myf3 , 9bact-a0a1s5ql04 , 9gamm-a0a1y0ihk7 , 9bact-a0a1s5qly6 , 9bact-a0a1s5qkg4 , 9bact-a0a1s5qkm4 , 9gamm-s5tv80 , 9gamm-a0a0c4zhg2 , 9zzzz-t1b379 , 9gamm-KY483646 , 9bact-KY458160 , 9zzzz-a0a0g3fj57 , 9gamm-s5t8349 , 9arch-KY203036 , 9bact-KY458168 , 9zzzz-a0a0g3fes0 , 9zzzz-t1be47 , 9bact-KY458159 , 9zzzz-a0a0g3fh39 , 9bact-t1vzd5 , 9prot-EH41 , 9bact-Lip114 , alcbs-q0vt77 , 9bact-a0a1s5qke6 , 9bact-a0a1s5qkf3 , 9prot-SRP030024 , 9gamm-s5t532 , 9bact-a0a1s5qkl2 , 9bact-a0a1s5qkk8 , 9zzzz-KY203030 , 9zzzz-t1d4I7 , 9prot-KY019260 , 9bact-a0a1s5qm38 , 9arch-KY458161 , 9prot-KY010302 , 9zzzz-a0a0g3fl25 , 9actn-KY010298 , 9gamm-s5u059 , 9bact-a0a1s5qmi7 , 9bact-KY010297 , 9bact-KY483642 , 9bact-a0a1s5qkj1 , 9bact-KY010299 , 9bact-KY483648 , alcbs-q0vtl7 , 9bact-a0a1s5qf1 , 9bact-a0a1s5qkg0 , 9bact-a0a0h4tgu6 , 9bact-MilE3 , 9bact-LAE6 , 9alte-MGS-MT1 , 9bact-r9qzf7 , 9gamm-k0c6t6 , alcbs-q0vl36 , alcbs-q0vlq1 , alcbs-q0vq49 , bacsu-pnbae , canar-LipB , canan-lipasA , geost-lipas , marav-a1u5n0 , pseps-i7k8x5 , staep-GEHD , symth-q67mr3 , altma-s5cfn7 , cycsp-k0c2b8 , alcbs-q0vlk5 , 9bact-k7qe48 , 9bact-MGS-M1 , 9bact-MGS-M2 , 9bact-a0a0b5kns5 , 9zzzz-a0a0g3fej4 , 9zzzz-a0a0g3fj60 , 9zzzz-a0a0g3fej0 , 9zzzz-a0a0g3fj64 , 9bact-a0a0b5kc16 , 9zzzz-a0a0g3feg6 , 9zzzz-a0a0g3feu6

Title : Functional Characterization of a Marine Bacillus Esterase and its Utilization in the Stereo-Selective Production of D-Methyl Lactate - Huang_2016_Appl.Biochem.Biotechnol_180_1467
Author(s) : Huang J , Zhang Y , Hu Y
Ref : Appl Biochem Biotechnol , 180 :1467 , 2016
Abstract : Huang_2016_Appl.Biochem.Biotechnol_180_1467
ESTHER : Huang_2016_Appl.Biochem.Biotechnol_180_1467
PubMedSearch : Huang_2016_Appl.Biochem.Biotechnol_180_1467
PubMedID: 27364331
Gene_locus related to this paper: bacsu-YITV

Title : Characterization of a novel marine microbial esterase and its use to make D-methyl lactate - Wang_2016_Chin.J.Catal_37_1396
Author(s) : Wang Y , Zhang Y , Sun A , Hu Y
Ref : Chinese Journal of Catalysis , 37 :1396 , 2016
Abstract : Wang_2016_Chin.J.Catal_37_1396
ESTHER : Wang_2016_Chin.J.Catal_37_1396
PubMedSearch : Wang_2016_Chin.J.Catal_37_1396
PubMedID:
Gene_locus related to this paper: 9psed-a0a1b1pfx3

Title : Lipase-catalyzed enantioselective synthesis of (R,R)-lactide from alkyl lactate to produce PDLA (poly D-lactic acid) and stereocomplex PLA (poly lactic acid) - Jeon_2013_J.Biotechnol_168_201
Author(s) : Jeon BW , Lee J , Kim HS , Cho DH , Lee H , Chang R , Kim YH
Ref : J Biotechnol , 168 :201 , 2013
Abstract : Jeon_2013_J.Biotechnol_168_201
ESTHER : Jeon_2013_J.Biotechnol_168_201
PubMedSearch : Jeon_2013_J.Biotechnol_168_201
PubMedID: 23845270
Gene_locus related to this paper: canar-LipB

Title : Lipase-catalyzed oligomerization and hydrolysis of alkyl lactates: direct evidence in the catalysis mechanism that enantioselection is governed by a deacylation step - Ohara_2010_Biomacromolecules_11_2008
Author(s) : Ohara H , Onogi A , Yamamoto M , Kobayashi S
Ref : Biomacromolecules , 11 :2008 , 2010
Abstract : Ohara_2010_Biomacromolecules_11_2008
ESTHER : Ohara_2010_Biomacromolecules_11_2008
PubMedSearch : Ohara_2010_Biomacromolecules_11_2008
PubMedID: 20593895