HODA-6-phenyl
General
Type : Meta-Cleavage-Product
Chemical_Nomenclature : (4Z)-2-Hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid
Canonical SMILES : C1=CC=C(C=C1)C(=CC=CC(=O)C(=O)O)O
InChI : InChI=1S\/C12H10O4\/c13-10(9-5-2-1-3-6-9)7-4-8-11(14)12(15)16\/h1-8,14H,(H,15,16)
InChIKey : YOVXRIACERVBAG-LJBIEAABSA-N
Other name(s) : 6-Hydroxy-2-oxo-6-phenylhexa-3,5-dienoic acid, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate, 2,6-Dioxo-6-phenylhexa-3-enoate, 6-phenyl-HODA, C01273
MW : 218.20
Formula : C12H10O4
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : Carbon-carbon_bond_hydrolase
References (8)
| Title : A substrate-assisted mechanism of nucleophile activation in a ser-his-asp containing C-C bond hydrolase - Ruzzini_2013_Biochemistry_52_7428 |
| Author(s) : Ruzzini AC , Bhowmik S , Ghosh S , Yam KC , Bolin JT , Eltis LD |
| Ref : Biochemistry , 52 :7428 , 2013 |
| Abstract : Ruzzini_2013_Biochemistry_52_7428 |
| ESTHER : Ruzzini_2013_Biochemistry_52_7428 |
| PubMedSearch : Ruzzini_2013_Biochemistry_52_7428 |
| PubMedID: 24067021 |
| Gene_locus related to this paper: sphww-a5j2a5 |
| Title : The Lid Domain of the MCP Hydrolase DxnB2 Contributes to the Reactivity toward Recalcitrant PCB Metabolites - Ruzzini_2013_Biochemistry_52_5685 |
| Author(s) : Ruzzini AC , Bhowmik S , Yam KC , Ghosh S , Bolin JT , Eltis LD |
| Ref : Biochemistry , 52 :5685 , 2013 |
| Abstract : Ruzzini_2013_Biochemistry_52_5685 |
| ESTHER : Ruzzini_2013_Biochemistry_52_5685 |
| PubMedSearch : Ruzzini_2013_Biochemistry_52_5685 |
| PubMedID: 23879719 |
| Gene_locus related to this paper: sphww-a5j2a5 |
| Title : Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad - Ruzzini_2012_J.Am.Chem.Soc_134_4615 |
| Author(s) : Ruzzini AC , Ghosh S , Horsman GP , Foster LJ , Bolin JT , Eltis LD |
| Ref : J Am Chem Soc , 134 :4615 , 2012 |
| Abstract : Ruzzini_2012_J.Am.Chem.Soc_134_4615 |
| ESTHER : Ruzzini_2012_J.Am.Chem.Soc_134_4615 |
| PubMedSearch : Ruzzini_2012_J.Am.Chem.Soc_134_4615 |
| PubMedID: 22339283 |
| Gene_locus related to this paper: burxl-bphD |
| Title : The molecular basis for inhibition of BphD, a C-C bond hydrolase involved in polychlorinated biphenyls degradation: large 3-substituents prevent tautomerization - Bhowmik_2007_J.Biol.Chem_282_36377 |
| Author(s) : Bhowmik S , Horsman GP , Bolin JT , Eltis LD |
| Ref : Journal of Biological Chemistry , 282 :36377 , 2007 |
| Abstract : Bhowmik_2007_J.Biol.Chem_282_36377 |
| ESTHER : Bhowmik_2007_J.Biol.Chem_282_36377 |
| PubMedSearch : Bhowmik_2007_J.Biol.Chem_282_36377 |
| PubMedID: 17932031 |
| Gene_locus related to this paper: burxl-bphD |
| Title : The tautomeric half-reaction of BphD, a C-C bond hydrolase. Kinetic and structural evidence supporting a key role for histidine 265 of the catalytic triad - Horsman_2007_J.Biol.Chem_282_19894 |
| Author(s) : Horsman GP , Bhowmik S , Seah SY , Kumar P , Bolin JT , Eltis LD |
| Ref : Journal of Biological Chemistry , 282 :19894 , 2007 |
| Abstract : Horsman_2007_J.Biol.Chem_282_19894 |
| ESTHER : Horsman_2007_J.Biol.Chem_282_19894 |
| PubMedSearch : Horsman_2007_J.Biol.Chem_282_19894 |
| PubMedID: 17442675 |
| Gene_locus related to this paper: burxl-bphD |
| Title : Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway - Horsman_2006_Biochemistry_45_11071 |
| Author(s) : Horsman GP , Ke J , Dai S , Seah SY , Bolin JT , Eltis LD |
| Ref : Biochemistry , 45 :11071 , 2006 |
| Abstract : Horsman_2006_Biochemistry_45_11071 |
| ESTHER : Horsman_2006_Biochemistry_45_11071 |
| PubMedSearch : Horsman_2006_Biochemistry_45_11071 |
| PubMedID: 16964968 |
| Gene_locus related to this paper: burxl-bphD |
| Title : A series of crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with various cleavage products - Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491 |
| Author(s) : Fushinobu S , Jun SY , Hidaka M , Nojiri H , Yamane H , Shoun H , Omori T , Wakagi T |
| Ref : Biosci Biotechnol Biochem , 69 :491 , 2005 |
| Abstract : Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491 |
| ESTHER : Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491 |
| PubMedSearch : Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491 |
| PubMedID: 15784976 |
| Gene_locus related to this paper: psefl-cumD |
| Title : Purification and preliminary characterization of a serine hydrolase involved in the microbial degradation of polychlorinated biphenyls - Seah_1998_J.Biol.Chem_273_22943 |
| Author(s) : Seah SY , Terracina G , Bolin JT , Riebel P , Snieckus V , Eltis LD |
| Ref : Journal of Biological Chemistry , 273 :22943 , 1998 |
| Abstract : Seah_1998_J.Biol.Chem_273_22943 |
| ESTHER : Seah_1998_J.Biol.Chem_273_22943 |
| PubMedSearch : Seah_1998_J.Biol.Chem_273_22943 |
| PubMedID: 9722515 |
| Gene_locus related to this paper: burxl-bphD |