Dienelactone

General

Type : Lactone

Chemical_Nomenclature : (2Z)-2-(5-oxofuran-2-ylidene)acetic acid

Canonical SMILES : C1=CC(=O)OC1=CC(=O)O

InChI : InChI=1S\/C6H4O4\/c7-5(8)3-4-1-2-6(9)10-4\/h1-3H,(H,7,8)\/b4-3-

InChIKey : AYFXPGXAZMFWNH-ONEGZZNKSA-N || AYFXPGXAZMFWNH-ARJAWSKDSA-N

Other name(s) : (5-oxofuran-2(5H)-ylidene)acetic acid,     Cis-4-carboxymethylenebut-2-en-4-olide,     (5-Oxo-2(5H)-furanylidene)acetic acid,     4-carboxymethylenebut-2-en-4-olide,     (2E)-(5-oxofuran-2(5H)-ylidene)acetic acid,     Trans-4-Carboxymethylenebut-2-en-4-olide,     AC1NQXEN,     SCHEMBL891606,     CHEBI:38107


MW : 140.09

Formula : C6H4O4

CAS_number : 73237-79-3 || 22752-92-7

PubChem :

UniChem :

Iuphar :

Target

References (8)

Title : Biochemical and structural characterization of a novel cold-active esterase-like protein from the psychrophilic yeast Glaciozyma antarctica - Hashim_2018_Extremophiles_22_607
Author(s) : Hashim NHF , Mahadi NM , Illias RM , Feroz SR , Abu Bakar FD , Murad AMA
Ref : Extremophiles , 22 :607 , 2018
Abstract : Hashim_2018_Extremophiles_22_607
ESTHER : Hashim_2018_Extremophiles_22_607
PubMedSearch : Hashim_2018_Extremophiles_22_607
PubMedID: 29556723
Gene_locus related to this paper: 9basi-a0a221se81

Title : Two structurally different dienelactone hydrolases (TfdEI and TfdEII) from Cupriavidus necator JMP134 plasmid pJP4 catalyse cis- and trans-dienelactones with similar efficiency - Kumar_2014_PLoS.One_9_e101801
Author(s) : Kumar A , Pillay B , Olaniran AO
Ref : PLoS ONE , 9 :e101801 , 2014
Abstract : Kumar_2014_PLoS.One_9_e101801
ESTHER : Kumar_2014_PLoS.One_9_e101801
PubMedSearch : Kumar_2014_PLoS.One_9_e101801
PubMedID: 25054964
Gene_locus related to this paper: alceu-tfe1 , alceu-tfe2

Title : Substrate-induced conformational change and isomerase activity of dienelactone hydrolase and its site-specific mutants - Walker_2012_Chembiochem_13_1645
Author(s) : Walker I , Hennessy JE , Ollis DL , Easton CJ
Ref : Chembiochem , 13 :1645 , 2012
Abstract : Walker_2012_Chembiochem_13_1645
ESTHER : Walker_2012_Chembiochem_13_1645
PubMedSearch : Walker_2012_Chembiochem_13_1645
PubMedID: 22761053

Title : Monitoring key reactions in degradation of chloroaromatics by in situ (1)H nuclear magnetic resonance: solution structures of metabolites formed from cis-dienelactone - Pieper_2002_J.Bacteriol_184_1466
Author(s) : Pieper DH , Pollmann K , Nikodem P , Gonzalez B , Wray V
Ref : Journal of Bacteriology , 184 :1466 , 2002
Abstract : Pieper_2002_J.Bacteriol_184_1466
ESTHER : Pieper_2002_J.Bacteriol_184_1466
PubMedSearch : Pieper_2002_J.Bacteriol_184_1466
PubMedID: 11844781

Title : Substrate-induced activation of dienelactone hydrolase: an enzyme with a naturally occurring Cys-His-Asp triad - Cheah_1993_Protein.Eng_6_575
Author(s) : Cheah E , Austin C , Ashley GW , Ollis D
Ref : Protein Engineering , 6 :575 , 1993
Abstract : Cheah_1993_Protein.Eng_6_575
ESTHER : Cheah_1993_Protein.Eng_6_575
PubMedSearch : Cheah_1993_Protein.Eng_6_575
PubMedID: 8234228
Gene_locus related to this paper: psepu-clcd1

Title : Catalysis by dienelactone hydrolase: a variation on the protease mechanism - Cheah_1993_Proteins_16_64
Author(s) : Cheah E , Ashley GW , Gary J , Ollis D
Ref : Proteins , 16 :64 , 1993
Abstract : Cheah_1993_Proteins_16_64
ESTHER : Cheah_1993_Proteins_16_64
PubMedSearch : Cheah_1993_Proteins_16_64
PubMedID: 8497485
Gene_locus related to this paper: psepu-clcd1

Title : Refined structure of dienelactone hydrolase at 1.8 A - Pathak_1990_J.Mol.Biol_214_497
Author(s) : Pathak D , Ollis D
Ref : Journal of Molecular Biology , 214 :497 , 1990
Abstract : Pathak_1990_J.Mol.Biol_214_497
ESTHER : Pathak_1990_J.Mol.Biol_214_497
PubMedSearch : Pathak_1990_J.Mol.Biol_214_497
PubMedID: 2380986
Gene_locus related to this paper: psepu-clcd1

Title : X-ray crystallographic structure of dienelactone hydrolase at 2.8 A - Pathak_1988_J.Mol.Biol_204_435
Author(s) : Pathak D , Ngai KL , Ollis D
Ref : Journal of Molecular Biology , 204 :435 , 1988
Abstract : Pathak_1988_J.Mol.Biol_204_435
ESTHER : Pathak_1988_J.Mol.Biol_204_435
PubMedSearch : Pathak_1988_J.Mol.Biol_204_435
PubMedID: 3221394
Gene_locus related to this paper: psepu-clcd1