Coelenterazine

General

Type : Luciferin || Natural

Chemical_Nomenclature : N-[2-benzyl-6-(4-oxocyclohexa-2,5-dien-1-ylidene)-1H-pyrazin-3-yl]-2-(4-hydroxyphenyl)acetamide

Canonical SMILES : C1=CC=C(C=C1)CC2=C(N=CC(=C3C=CC(=O)C=C3)N2)NC(=O)CC4=CC=C(C=C4)O

InChI : InChI=1S\/C25H21N3O3\/c29-20-10-6-18(7-11-20)15-24(31)28-25-22(14-17-4-2-1-3-5-17)27-23(16-26-25)19-8-12-21(30)13-9-19\/h1-13,16,27,29H,14-15H2,(H,28,31)

InChIKey : YHIPILPTUVMWQT-UHFFFAOYSA-N

Other name(s) : Oplophorus luciferin,     55779-48-1,     CLZN,     CTZ,     Coelenterazine ,native


MW : 423.46

Formula : C26H21N3O3

CAS_number :

PubChem :

UniChem :

Iuphar :

Target

References (4)

Title : Deciphering Enzyme Mechanisms with Engineered Ancestors and Substrate Analogues - Gao_2023_ChemCatChem_15_e202300745
Author(s) : Gao T , Damborsky J , Janin YL , Marek M
Ref : ChemCatChem , 15 :e202300745 , 2023
Abstract : Gao_2023_ChemCatChem_15_e202300745
ESTHER : Gao_2023_ChemCatChem_15_e202300745
PubMedSearch : Gao_2023_ChemCatChem_15_e202300745
PubMedID:
Gene_locus related to this paper: renre-luc

Title : Light-Emitting Dehalogenases: Reconstruction of Multifunctional Biocatalysts - Chaloupkova_2019_ACS.Catal_9_48103
Author(s) : Chaloupkova, R , Liskova V , Tool M , Markova K , Sebestova E , Hernychova L , Marek M , Pinto GP , Pluskal D , Waterman J , Prokop Z , Damborsky J
Ref : ACS Catal , 9 :4810 , 2019
Abstract : Chaloupkova_2019_ACS.Catal_9_48103
ESTHER : Chaloupkova_2019_ACS.Catal_9_48103
PubMedSearch : Chaloupkova_2019_ACS.Catal_9_48103
PubMedID:
Gene_locus related to this paper: 9zzzz-AncHLDRLuc2 , 9zzzz-AncHLDRLuc , renre-luc

Title : Structure-function studies on the active site of the coelenterazine-dependent luciferase from Renilla - Woo_2008_Protein.Sci_17_725
Author(s) : Woo J , Howell MH , von Arnim AG
Ref : Protein Science , 17 :725 , 2008
Abstract : Woo_2008_Protein.Sci_17_725
ESTHER : Woo_2008_Protein.Sci_17_725
PubMedSearch : Woo_2008_Protein.Sci_17_725
PubMedID: 18359861
Gene_locus related to this paper: renre-luc

Title : Crystal structures of the luciferase and green fluorescent protein from Renilla reniformis - Loening_2007_J.Mol.Biol_374_1017
Author(s) : Loening AM , Fenn TD , Gambhir SS
Ref : Journal of Molecular Biology , 374 :1017 , 2007
Abstract : Loening_2007_J.Mol.Biol_374_1017
ESTHER : Loening_2007_J.Mol.Biol_374_1017
PubMedSearch : Loening_2007_J.Mol.Biol_374_1017
PubMedID: 17980388
Gene_locus related to this paper: renre-luc