Carbachol
General
Type : Drug || Not A\/B H target || Carbamate || Trimethylammonium || Choline ester || Analogue of substrate
Chemical_Nomenclature : 2-[(Aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride\; (2-hydroxyethyl)trimethylammonium chloride carbamate \; 2-carbamoyloxyethyl-trimethyl-ammonium
Canonical SMILES : C[N+](C)(C)CCOC(=O)N.[Cl-]
InChI : InChI=1S\/C6H14N2O2.ClH\/c1-8(2,3)4-5-10-6(7)9\;\/h4-5H2,1-3H3,(H-,7,9)\;1H
InChIKey : AIXAANGOTKPUOY-UHFFFAOYSA-N
Other name(s) : Carbamylcholine, Carbacholin, Carbacholine, Carbacolina, Carbamiotin, Carbocholin, Carbocholine, Carbochol, Carcholin, Miostat, Carbacholinum, Karbachol, carbamylcholine chloride
Target
Families : ACHE
References (3)
| Title : Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase - Auletta_2010_Chem.Biol.Interact_187_135 |
| Author(s) : Auletta JT , Johnson JL , Rosenberry TL |
| Ref : Chemico-Biological Interactions , 187 :135 , 2010 |
| Abstract : Auletta_2010_Chem.Biol.Interact_187_135 |
| ESTHER : Auletta_2010_Chem.Biol.Interact_187_135 |
| PubMedSearch : Auletta_2010_Chem.Biol.Interact_187_135 |
| PubMedID: 20493829 |
| Title : Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter - Rosenberry_2008_Biochemistry_47_13056 |
| Author(s) : Rosenberry TL , Sonoda LK , Dekat SE , Cusack B , Johnson JL |
| Ref : Biochemistry , 47 :13056 , 2008 |
| Abstract : Rosenberry_2008_Biochemistry_47_13056 |
| ESTHER : Rosenberry_2008_Biochemistry_47_13056 |
| PubMedSearch : Rosenberry_2008_Biochemistry_47_13056 |
| PubMedID: 19006330 |
| Title : Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis - Rosenberry_2008_Chem.Biol.Interact_175_235 |
| Author(s) : Rosenberry TL , Sonoda LK , Dekat SE , Cusack B , Johnson JL |
| Ref : Chemico-Biological Interactions , 175 :235 , 2008 |
| Abstract : Rosenberry_2008_Chem.Biol.Interact_175_235 |
| ESTHER : Rosenberry_2008_Chem.Biol.Interact_175_235 |
| PubMedSearch : Rosenberry_2008_Chem.Biol.Interact_175_235 |
| PubMedID: 18602908 |