Type : Mycotoxin-metabolite || Macrolide || Natural || Toxin
Chemical_Nomenclature : (2E,7R,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraen-13-one
Canonical SMILES : CC1CCCC(CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O)O
InChI : InChI=1S\/C18H24O5\/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12\/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3\/b7-3+\/t12-,14+\/m0\/s1
InChIKey : FPQFYIAXQDXNOR-QDKLYSGJSA-N
Other name(s) : Alpha-Zearalenol, Trans-Zearalenol, Zearalenol, Cis-Zearalenol, Alpha zearalenol, Alpha-ZOL, (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, 36J
Families : Zearalenone-hydrolase
Title : The Trp183 is essential in lactonohydrolase ZHD detoxifying zearalenone and zearalenols - Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
Author(s) : Zhou H , Li L , Zhan B , Wang S , Li J , Hu XJ |
Ref : Biochemical & Biophysical Research Communications , 522 :986 , 2020 |
Abstract : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
ESTHER : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
PubMedSearch : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
PubMedID: 31810602 |
Gene_locus related to this paper: biooc-ZHD101 |
Title : Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity - Zheng_2018_ACS.Catal_8_4294 |
Author(s) : Zheng YY , Liu WT , Chen CC , Hu XY , Liu WD , Ko TP , Tang XK , Wei HL , Huang JW , Guo RT |
Ref : ACS Catal , 8 :4294 , 2018 |
Abstract : Zheng_2018_ACS.Catal_8_4294 |
ESTHER : Zheng_2018_ACS.Catal_8_4294 |
PubMedSearch : Zheng_2018_ACS.Catal_8_4294 |
PubMedID: |
Gene_locus related to this paper: 9euro-a0a0d2ilk1 |
Title : Enhanced alpha-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering - Xu_2016_ACS.Catal_6_7657 |
Author(s) : Xu Z , Liu W , Chen CC , Li Q , Huang JW , Ko TP , Liu G , Peng W , Cheng YS , Chen Y , Jin J , Li H , Zheng Y , Guo RT |
Ref : ACS Catal , 6 :7657 , 2016 |
Abstract : Xu_2016_ACS.Catal_6_7657 |
ESTHER : Xu_2016_ACS.Catal_6_7657 |
PubMedSearch : Xu_2016_ACS.Catal_6_7657 |
PubMedID: |
Gene_locus related to this paper: biooc-ZHD101 |