Ac-Leu-p-nitroanilide

General

Type : Peptide || p-nitroaniline || pNP || Chromogen

Chemical_Nomenclature : (2S)-2-acetamido-4-methyl-N-(4-nitrophenyl)pentanamide

Canonical SMILES : CC(C)CC(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C

InChI : InChI=1S\/C14H19N3O4\/c1-9(2)8-13(15-10(3)18)14(19)16-11-4-6-12(7-5-11)17(20)21\/h4-7,9,13H,8H2,1-3H3,(H,15,18)(H,16,19)\/t13-\/m0\/s1

InChIKey : SLJKQHDBYBGOMH-ZDUSSCGKSA-N

Other name(s) : Ac-Leu-pNA,     N-Acetyl-L-leucine-p-nitroanilide,     Acetyl-L-leucine 4-nitroanilide,     AC1OLQVE,     CTK8F7540


MW : 293.32

Formula : C14H19N3O4

CAS_number : 19746-40-8

PubChem :

UniChem :

Iuphar :

Target

Families : ACPH_Peptidase_S9

References (3)

Title : Understanding the interactions of different substrates with wild-type and mutant acylaminoacyl peptidase using molecular dynamics simulations - Zhu_2017_J.Biomol.Struct.Dyn__1
Author(s) : Zhu J , Wang Y , Li X , Han W , Zhao L
Ref : J Biomol Struct Dyn , :1 , 2017
Abstract : Zhu_2017_J.Biomol.Struct.Dyn__1
ESTHER : Zhu_2017_J.Biomol.Struct.Dyn__1
PubMedSearch : Zhu_2017_J.Biomol.Struct.Dyn__1
PubMedID: 29235404
Gene_locus related to this paper: aerpe-APE1547

Title : Exploration of the chlorpyrifos escape pathway from acylpeptide hydrolases using steered molecular dynamics simulations - Wang_2016_J.Biomol.Struct.Dyn_34_749
Author(s) : Wang D , Jin H , Wang J , Guan S , Zhang Z , Han W
Ref : J Biomol Struct Dyn , 34 :749 , 2016
Abstract : Wang_2016_J.Biomol.Struct.Dyn_34_749
ESTHER : Wang_2016_J.Biomol.Struct.Dyn_34_749
PubMedSearch : Wang_2016_J.Biomol.Struct.Dyn_34_749
PubMedID: 26155973
Gene_locus related to this paper: aerpe-APE1547

Title : Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation - Wang_2006_J.Biol.Chem_281_18618
Author(s) : Wang Q , Yang G , Liu Y , Feng Y
Ref : Journal of Biological Chemistry , 281 :18618 , 2006
Abstract : Wang_2006_J.Biol.Chem_281_18618
ESTHER : Wang_2006_J.Biol.Chem_281_18618
PubMedSearch : Wang_2006_J.Biol.Chem_281_18618
PubMedID: 16670095
Gene_locus related to this paper: aerpe-APE1547