10-Deoxymethynolide
General
Type : Polyketide || Macrolide
Chemical_Nomenclature : (3R,4S,5S,7R,9E,11R,12R)-12-ethyl-4-hydroxy-3,5,7,11-tetramethyl-1-oxacyclododec-9-ene-2,8-dione
Canonical SMILES : CCC1C(C=CC(=O)C(CC(C(C(C(=O)O1)C)O)C)C)C
InChI : InChI=1S\/C17H28O4\/c1-6-15-10(2)7-8-14(18)11(3)9-12(4)16(19)13(5)17(20)21-15\/h7-8,10-13,15-16,19H,6,9H2,1-5H3\/b8-7+\/t10-,11-,12+,13-,15-,16+\/m1\/s1
InChIKey : NZUJVBSYQXETNF-PQWITYJESA-N
Other name(s) : E4H, DB07703, 81644-19-1, (3R,4S,5S,7R,9E,11R,12R)-12-ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione, AC1NQZDU, SCHEMBL2880039, CHEBI:29461
MW : 296.40
Formula : C17H28O4
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : Thioesterase
References (1)
| Title : Structural basis for macrolactonization by the pikromycin thioesterase - Akey_2006_Nat.Chem.Biol_2_537 |
| Author(s) : Akey DL , Kittendorf JD , Giraldes JW , Fecik RA , Sherman DH , Smith JL |
| Ref : Nat Chemical Biology , 2 :537 , 2006 |
| Abstract : Akey_2006_Nat.Chem.Biol_2_537 |
| ESTHER : Akey_2006_Nat.Chem.Biol_2_537 |
| PubMedSearch : Akey_2006_Nat.Chem.Biol_2_537 |
| PubMedID: 16969372 |
| Gene_locus related to this paper: strve-PIKAIV |