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Structure Report for: 4UZQ

Name|Structure of th humane wnt deacetylase notum in complex with O-Palmitoleoyl serine- Crystal form IX - 1.5A
Revelation date|25-Feb-2015
Family|Pectinacetylesterase-Notum: there are 695 genes in this family, 143 structure(s)
Gene_locus|human-NOTUM
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Kakugawa, S., Langton, P.F., Zebisch, M., Howell, S.A., Chang, T.-H., Liu, Y., Feizi, T., Bineva, G., O'Reilly, N., Snijders, A.P., Jones, E.Y., Vincent, J.-P.
Ligand|Substrate: O-palmitoleoyl-L-serine Ligand in structure: Ligplot Inhibitor: Palmitoleic-acid Ligand in structure: Ligplot


Reference

    Title: Notum deacylates Wnt proteins to suppress signalling activity
    Kakugawa S, Langton PF, Zebisch M, Howell SA, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N and Vincent JP <2 more author(s)>
    Ref: Nature, 519:187, 2015 : PubMed

            



Representative scheme of Pectinacetylesterase-Notum structure and an image from PDBsum server

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Databases

PDB-Sum4UZQ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4UZQ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4UZQ Structural Classification Of Protein - SCOP server
PROTEOPEDIA4uzq 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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