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Structure Report for: 2ONC

Name|Crystal structure of human DPP-4 with inhibitor Alogliptin
Revelation date|04-Mar-2008
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 182 structure(s)
Gene_locus|human-DPP4
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Feng, J., Zhang, Z., Wallace, M.B., Stafford, J.A., Kaldor, S.W., Kassel, D.B., Navre, M., Shi, L., Skene, R.J., Asakawa, T., Takeuchi, K., Xu, R., Webb, D.R., Gwaltney, S.L.
Ligand|Inhibitor: Alogliptin Ligand in structure: Ligplot


Reference

    Title: Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV
    Feng J, Zhang Z, Wallace MB, Stafford JA, Kaldor SW, Kassel DB, Navre M, Shi L, Skene RJ and Gwaltney SL, 2nd <4 more author(s)>
    Ref: Journal of Medicinal Chemistry, 50:2297, 2007 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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Databases

PDB-Sum2ONC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2ONC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2ONC Structural Classification Of Protein - SCOP server
PROTEOPEDIA2onc 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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