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Paper Report for: Wang_2011_Bioorg.Med.Chem.Lett_21_6646

Reference

Title: 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site
Wang W, Devasthale P, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE and Hamann LG <7 more author(s)>
Ref: Bioorganic & Medicinal Chemistry Lett, 21:6646, 2011 : PubMed

        



Related information

Gene_Locus| human-DPP4
Structure in RCSB-PDB | 3SWW, 3SX4
Structure in ESTHER | 3SWW, 3SX4
Inhibitor | CHEMBL1910114, CHEMBL1909991,


Citations formats

Wang W, Devasthale P, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE, Kish K, Weigelt C, Sun L, Levesque P, Li YX, Zahler R, Kirby MS, Hamann LG (2011)
7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site
Bioorganic & Medicinal Chemistry Lett 21: 6646-51

Wang W, Devasthale P, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE, Kish K, Weigelt C, Sun L, Levesque P, Li YX, Zahler R, Kirby MS, Hamann LG (2011)
Bioorganic & Medicinal Chemistry Lett 21: 6646-51



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