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Paper Report for: Rydberg_2006_J.Med.Chem_49_5491

Reference

Title: Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge
Rydberg EH, Brumshtein B, Greenblatt HM, Wong DM, Shaya D, Williams LD, Carlier PR, Pang YP, Silman I, Sussman JL
Ref: Journal of Medicinal Chemistry, 49:5491, 2006 : PubMed

        



Related information

Gene_Locus| torca-ACHE
Structure in RCSB-PDB | 2CMF, 2CKM, 1ODC, 1UT6
Structure in ESTHER | 2CMF, 2CKM, 1ODC, 1UT6
Inhibitor | Tacrine(8)-4-aminoquinoline, N-ammoniooctyl-tacrine, Bis5-tacrine, Bis7-tacrine, Bis3-tacrine,


Citations formats

Rydberg EH, Brumshtein B, Greenblatt HM, Wong DM, Shaya D, Williams LD, Carlier PR, Pang YP, Silman I, Sussman JL (2006)
Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge
Journal of Medicinal Chemistry 49: 5491-500

Rydberg EH, Brumshtein B, Greenblatt HM, Wong DM, Shaya D, Williams LD, Carlier PR, Pang YP, Silman I, Sussman JL (2006)
Journal of Medicinal Chemistry 49: 5491-500



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