A method for the partial purification of rat liver paraoxonase is presented. The method consists of the following steps: preparation of microsomes, solubilization with Triton X-100, adsorption on hydroxylapatite and chromatography on DEAE-52 cellulose. A partially purified preparation of rat liver paraoxonase has been obtained, showing a specific activity of 422 mU/mg with a yield of about 22% and a purification factor of 77-fold.
        
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Gil F, Pla A, Gonzalvo MC, Hernandez AF, Villanueva E (1993) Partial purification of paraoxonase from rat liver Chemico-Biological Interactions87: 69-75
Gil F, Pla A, Gonzalvo MC, Hernandez AF, Villanueva E (1993) Chemico-Biological Interactions87: 69-75