Gene Locus : brafl-ACHE1
Mode of mutation : Site directed mutagenesis
Disease :
Summary : OP-resistance\;The mutation virtually abolishes the difference in sensitivity to the inhibitors\;Patel_2006_Cell.Biochem.Biophys_46_253
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : OP-resistance
Torpedo_number : 331
Kinetic Parameter : No kinetic parameter
News : FEBRUARY-08-2007
Comment : p.Trp353Phe
| Title : A tryptophan in the bottleneck of the catalytic gorge of an invertebrate acetylcholinesterase confers relative resistance to carbamate and organophosphate inhibitors - Patel_2006_Cell.Biochem.Biophys_46_253 |
| Author(s) : Patel R , Sanders R , Brown L , Baker S , Tsigelny I , Pezzementi L |
| Ref : Cell Biochem Biophys , 46 :253 , 2006 |
| Abstract : Patel_2006_Cell.Biochem.Biophys_46_253 |
| ESTHER : Patel_2006_Cell.Biochem.Biophys_46_253 |
| PubMedSearch : Patel_2006_Cell.Biochem.Biophys_46_253 |
| PubMedID: 17272851 |