Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Succinylthiocholine binding\;Probable disorganization of the active site\;Masson_1997_Biochemistry_36_2266
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Succinylthiocholine binding
Torpedo_number : 233
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.W231A Trp231Ala (p.W259A Trp259Ala in primary sequence with 28 amino-acids signal peptide) Succinylthiocholine binding\;Probable disorganization of the active site
| Title : Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase - Masson_1997_Biochemistry_36_2266 |
| Author(s) : Masson P , Legrand P , Bartels CF , Froment MT , Schopfer LM , Lockridge O |
| Ref : Biochemistry , 36 :2266 , 1997 |
| Abstract : Masson_1997_Biochemistry_36_2266 |
| ESTHER : Masson_1997_Biochemistry_36_2266 |
| PubMedSearch : Masson_1997_Biochemistry_36_2266 |
| PubMedID: 9047329 |