I82M_musdo-ACHE

General

Gene Locus : musdo-ACHE

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance NO EFFECT sensitivity to fenitroxon Kozaki_2001_Insect.Biochem.Mol.Biol_31_991 || OP-resistance No effect of this single mutation Kim_2003_Mol.Cells_15_208

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 83

Kinetic Parameter : No kinetic parameter

News : No news

Comment : NO EFFECT. Sensitivity to fenitroxon. I82M corresponds to the noted I162M in the paper Kozaki_2001_Insect.Biochem.Mol.Biol_31_991. We do not count the signal peptide in order to be in accordance with the mutation numbering of Walsh_2001_Biochem.J_359_175 paper || p.Ile82Met

References (3)

Title : Propoxur resistance associated with insensitivity of acetylcholinesterase (AChE) in the housefly, Musca domestica (Diptera: Muscidae) - You_2020_Sci.Rep_10_8400
Author(s) : You C , Shan C , Xin J , Li J , Ma Z , Zhang Y , Zeng X , Gao X
Ref : Sci Rep , 10 :8400 , 2020
Abstract : You_2020_Sci.Rep_10_8400
ESTHER : You_2020_Sci.Rep_10_8400
PubMedSearch : You_2020_Sci.Rep_10_8400
PubMedID: 32439946

Title : Cloning, mutagenesis, and expression of the acetylcholinesterase gene from a strain of Musca domestica\; the change from a drug-resistant to a sensitive enzyme - Kim_2003_Mol.Cells_15_208
Author(s) : Kim CS , Kim WT , Boo KS , Kim SI
Ref : Mol Cells , 15 :208 , 2003
Abstract : Kim_2003_Mol.Cells_15_208
ESTHER : Kim_2003_Mol.Cells_15_208
PubMedSearch : Kim_2003_Mol.Cells_15_208
PubMedID: 12803484
Gene_locus related to this paper: musdo-ACHE

Title : Fenitroxon insensitive acetylcholinesterases of the housefly, Musca domestica associated with point mutations - Kozaki_2001_Insect.Biochem.Mol.Biol_31_991
Author(s) : Kozaki T , Shono T , Tomita T , Kono Y
Ref : Insect Biochemistry & Molecular Biology , 31 :991 , 2001
Abstract : Kozaki_2001_Insect.Biochem.Mol.Biol_31_991
ESTHER : Kozaki_2001_Insect.Biochem.Mol.Biol_31_991
PubMedSearch : Kozaki_2001_Insect.Biochem.Mol.Biol_31_991
PubMedID: 11483435
Gene_locus related to this paper: musdo-ACHE