G534X_human-BCHE

General

Gene Locus : human-BCHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Minimal C-term determination gives an active monomere Blong_1995_5th.ChE.Meeting.Madras__129 Blong_1997_Biochem.J_327_747

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Minimal C-term determination

Torpedo_number : 536

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.G534X Gly534Ter (p.G562X Gly562Ter in primary sequence with 28 amino-acids signal peptide) Minimal C-term determination\;gives an active monomere

References (2)

Title : Tetramerization domain of human butyrylcholinesterase is at the C- terminus - Blong_1997_Biochem.J_327_747
Author(s) : Blong RM , Bedows E , Lockridge O
Ref : Biochemical Journal , 327 :747 , 1997
Abstract : Blong_1997_Biochem.J_327_747
ESTHER : Blong_1997_Biochem.J_327_747
PubMedSearch : Blong_1997_Biochem.J_327_747
PubMedID: 9581552

Title : Subunit Association and Stabilization of Butyrylcholinesterase (BChE) -
Author(s) : Blong RM , Masson P , Lockridge O
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :129 , 1995
PubMedID: