C580S_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Subunit assembly Dimerization deficient mutant Fischer_1993_Cell.Mol.Neurobiol_13_25 Fischer_1995_Biotechnol.App.Biochem_21_295

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Subunit assembly

Torpedo_number : 572

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.C580S Cys580Ser (p.C611S Cys611Ser in primary sequence with 31 amino-acids signal peptide) Subunit assembly\;Dimerization deficient mutant

References (2)

Title : Recombinant human acetylcholinesterase expressed in Escherichia coli: refolding, purification and characterization - Fischer_1995_Biotechno.App.Biochem_21_295
Author(s) : Fischer M , Ittah A , Gorecki M , Werber MM
Ref : Biotechnol Appl Biochem , 21 :295 , 1995
Abstract : Fischer_1995_Biotechno.App.Biochem_21_295
ESTHER : Fischer_1995_Biotechno.App.Biochem_21_295
PubMedSearch : Fischer_1995_Biotechno.App.Biochem_21_295
PubMedID: 7794533

Title : Expression and reconstitution of biologically active human acetylcholinesterase from Escherichia coli - Fischer_1993_Cell.Mol.Neurobiol_13_25
Author(s) : Fischer M , Ittah A , Liefer I , Gorecki M
Ref : Cellular Molecular Neurobiology , 13 :25 , 1993
Abstract : Fischer_1993_Cell.Mol.Neurobiol_13_25
ESTHER : Fischer_1993_Cell.Mol.Neurobiol_13_25
PubMedSearch : Fischer_1993_Cell.Mol.Neurobiol_13_25
PubMedID: 8458061