A328C_human-BCHE

General

Gene Locus : human-BCHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Active mutant Lushchekina_2016_Chem.Biol.Interact_259_223

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : 330

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.A328C Ala328Cys (p.A356C Ala356Cys in primary sequence with 28 amino-acids signal peptide) catalically active mutant used in comparison of the silent variant p.Ala328Asp

References (1)

Title : Understanding the non-catalytic behavior of human butyrylcholinesterase silent variants: comparison of wild-type enzyme, catalytically active Ala328Cys mutant, and silent Ala328Asp variant - Lushchekina_2016_Chem.Biol.Interact_259_223
Author(s) : Lushchekina SV , Nemukhin AV , Varfolomeev SD , Masson P
Ref : Chemico-Biological Interactions , 259 :223 , 2016
Abstract : Lushchekina_2016_Chem.Biol.Interact_259_223
ESTHER : Lushchekina_2016_Chem.Biol.Interact_259_223
PubMedSearch : Lushchekina_2016_Chem.Biol.Interact_259_223
PubMedID: 27062896